Abby R Rosenberg1,2,3, Chuan Zhou4,5, Miranda C Bradford5, Krysta Barton1,5, Courtney C Junkins1, Mallory Taylor1,2,3, Erin K Kross3,6, J Randall Curtis3,6, J Nicholas Dionne-Odom7, Joyce P Yi-Frazier1. 1. Palliative Care and Resilience Research Laboratory, Center for Clinical and Translational Research, Epidemiology, and Analytics in Research Program, Seattle Children's Research Institute, Seattle, Washington, USA. 2. Divisions of Hematology/Oncology, Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington, USA. 3. Cambia Palliative Care Center of Excellence, University of Washington, Seattle, Washington, USA. 4. Divisions of General Pediatrics, Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington, USA. 5. Biostatistics, Epidemiology, and Analytics in Research Program, Seattle Children's Research Institute, Seattle, Washington, USA. 6. Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Washington, Seattle, Washington, USA. 7. Department of Acute, Chronic, and Continuing Care, University of Alabama at Birmingham School of Nursing, Birmingham, Alabama, USA.
Abstract
Background: Parents experience high distress following their child's diagnosis of cancer. We previously tested two delivery models (group and one-on-one) of the "Promoting Resilience in Stress Management for Parents" (PRISM-P) intervention in a randomized trial: one-on-one delivery improved resilience and benefit finding at three months when compared to usual care (UC). Objective: The objective of this analysis was to evaluate quantitative and qualitative outcomes at six months. Design: In this single-center, phase 2, parallel, 1:1:1 randomized trial conducted December 2016 to December 2018, English-speaking parents with a 2-24 year-old child diagnosed with new cancer were randomly assigned to UC, one-on-one, or group PRISM-P, a brief, skill-based curriculum targeting stress management, goal setting, cognitive reframing, and meaning making. We collected parent-reported outcomes (resilience, benefit finding, and psychological distress) at baseline and three and six months. We applied linear mixed-effects regression models to examine six-month outcomes among all participants and conducted directed content analyses of exit interviews with the first 12 parents to complete each study arm. Results: The 94 participating parents were median aged 35-38 years and predominantly white, college-educated mothers. At six months, there was no statistically significant difference in parent-reported outcomes. Exit interviews (n = 36) suggested that PRISM-P was highly valued: 100% of interviewed recipients recommended it for other parents. Most suggested more coaching would help them retain skills, and almost all endorsed a combined one-on-one and group program. Conclusions: Although the PRISM-P benefits observed at three months were not sustained for six months, all interviewed parents found it valuable. Additional opportunities to strengthen and sustain resilience resources include longer follow-up, flexible format, and skill reinforcement. Trial Registration: NCT02998086.
Background: Parents experience high distress following their child's diagnosis of cancer. We previously tested two delivery models (group and one-on-one) of the "Promoting Resilience in Stress Management for Parents" (PRISM-P) intervention in a randomized trial: one-on-one delivery improved resilience and benefit finding at three months when compared to usual care (UC). Objective: The objective of this analysis was to evaluate quantitative and qualitative outcomes at six months. Design: In this single-center, phase 2, parallel, 1:1:1 randomized trial conducted December 2016 to December 2018, English-speaking parents with a 2-24 year-old child diagnosed with new cancer were randomly assigned to UC, one-on-one, or group PRISM-P, a brief, skill-based curriculum targeting stress management, goal setting, cognitive reframing, and meaning making. We collected parent-reported outcomes (resilience, benefit finding, and psychological distress) at baseline and three and six months. We applied linear mixed-effects regression models to examine six-month outcomes among all participants and conducted directed content analyses of exit interviews with the first 12 parents to complete each study arm. Results: The 94 participating parents were median aged 35-38 years and predominantly white, college-educated mothers. At six months, there was no statistically significant difference in parent-reported outcomes. Exit interviews (n = 36) suggested that PRISM-P was highly valued: 100% of interviewed recipients recommended it for other parents. Most suggested more coaching would help them retain skills, and almost all endorsed a combined one-on-one and group program. Conclusions: Although the PRISM-P benefits observed at three months were not sustained for six months, all interviewed parents found it valuable. Additional opportunities to strengthen and sustain resilience resources include longer follow-up, flexible format, and skill reinforcement. Trial Registration: NCT02998086.
Authors: Abby R Rosenberg; Miranda C Bradford; Kira Bona; Michele L Shaffer; Joanne Wolfe; K Scott Baker; Nancy Lau; Joyce Yi-Frazier Journal: J Psychosoc Oncol Date: 2017-11-03
Authors: Olle Jane Z Sahler; Michael J Dolgin; Sean Phipps; Diane L Fairclough; Martha A Askins; Ernest R Katz; Robert B Noll; Robert W Butler Journal: J Clin Oncol Date: 2013-01-28 Impact factor: 44.544
Authors: Martha A Askins; Olle Jane Z Sahler; Sandra A Sherman; Diane L Fairclough; Robert W Butler; Ernest R Katz; Michael J Dolgin; James W Varni; Robert B Noll; Sean Phipps Journal: J Pediatr Psychol Date: 2008-12-17
Authors: Anne E Kazak; Annah N Abrams; Jaime Banks; Jennifer Christofferson; Stephen DiDonato; Martha A Grootenhuis; Marianne Kabour; Avi Madan-Swain; Sunita K Patel; Sima Zadeh; Mary Jo Kupst Journal: Pediatr Blood Cancer Date: 2015-12 Impact factor: 3.167
Authors: Courtney C Junkins; Erin Kent; Kristin Litzelman; Margaret Bevans; Rachel S Cannady; Abby R Rosenberg Journal: J Psychosoc Oncol Date: 2020-08-12