OBJECTIVE: We aimed to assess the incidence, management, and visual outcome of acute endophthalmitis in patients following intravitreal bevacizumab injection in a tertiary care setup. It was a prospective and single-center database study. PATIENTS AND METHODS: Patients receiving intravitreal bevacizumab injections for various retinal vascular diseases from January 2019 to September 2020. The study was carried out at the Institute of Ophthalmology, Mayo Hospital, Lahore over a period of 21 months. Preformed bevacizumab injections were administered intravitreally on patients of various retinal vascular diseases under strict aseptic measures and by following the standard guidelines. The patients were put on follow-ups for a duration of four weeks to see any signs of acute endophthalmitis. RESULTS: A total of 3051 injections were administered in 1104 eyes of 743 patients during the above-mentioned study period. The incidence of endophthalmitis was found to be 0.0328% (1/3051). The patient, who developed endophthalmitis, was treated with topical and intravitreal antibiotics followed by vitrectomy that resulted in clinically significant improvement in vision. CONCLUSION: Incidence of acute endophthalmitis following intravitreal bevacizumab injection was low and could be prevented by taking strict aseptic measures during administration.
OBJECTIVE: We aimed to assess the incidence, management, and visual outcome of acute endophthalmitis in patients following intravitreal bevacizumab injection in a tertiary care setup. It was a prospective and single-center database study. PATIENTS AND METHODS: Patients receiving intravitreal bevacizumab injections for various retinal vascular diseases from January 2019 to September 2020. The study was carried out at the Institute of Ophthalmology, Mayo Hospital, Lahore over a period of 21 months. Preformed bevacizumab injections were administered intravitreally on patients of various retinal vascular diseases under strict aseptic measures and by following the standard guidelines. The patients were put on follow-ups for a duration of four weeks to see any signs of acute endophthalmitis. RESULTS: A total of 3051 injections were administered in 1104 eyes of 743 patients during the above-mentioned study period. The incidence of endophthalmitis was found to be 0.0328% (1/3051). The patient, who developed endophthalmitis, was treated with topical and intravitreal antibiotics followed by vitrectomy that resulted in clinically significant improvement in vision. CONCLUSION: Incidence of acute endophthalmitis following intravitreal bevacizumab injection was low and could be prevented by taking strict aseptic measures during administration.
Authors: Ingrid U Scott; Allison R Edwards; Roy W Beck; Neil M Bressler; Clement K Chan; Michael J Elman; Scott M Friedman; Craig Michael Greven; Raj K Maturi; Dante J Pieramici; Michel Shami; Lawrence J Singerman; Cynthia R Stockdale Journal: Ophthalmology Date: 2007-08-15 Impact factor: 12.079
Authors: Vincent Daien; Vuong Nguyen; Rohan W Essex; Nigel Morlet; Daniel Barthelmes; Mark C Gillies Journal: Ophthalmology Date: 2017-08-08 Impact factor: 12.079
Authors: Philip P Storey; Zujaja Tauqeer; Yoshihiro Yonekawa; Bozho Todorich; Jeremy D Wolfe; Sumit P Shah; Ankoor R Shah; Takashi Koto; Ashkan M Abbey; Yuki Morizane; Priya Sharma; Edward H Wood; Mio Morizane-Hosokawa; Pooja Pendri; Maitri Pancholy; Shawn Harkey; Karen W Jeng-Miller; Anthony Obeid; Durga S Borkar; Eric Chen; Patrick Williams; Annabelle A Okada; Makoto Inoue; Fumio Shiraga; Akito Hirakata; Chirag P Shah; Jonathan Prenner; Sunir Garg Journal: Am J Ophthalmol Date: 2018-12-13 Impact factor: 5.258
Authors: A M E Schauwvlieghe; G Dijkman; J M Hooymans; F D Verbraak; C B Hoyng; M G W Dijkgraaf; T Peto; J R Vingerling; R O Schlingemann Journal: PLoS One Date: 2016-05-20 Impact factor: 3.240