Literature DB >> 33716619

Implementing a digital infrastructure for the lab using a central laboratory server and the SiLA2 communication standard.

Marc Porr1, Ferdinand Lange1, Daniel Marquard1, Laura Niemeyer1, Patrick Lindner1, Thomas Scheper1, Sascha Beutel1.   

Abstract

In this report, a fully integrated solution for laboratory digitization is presented. The approach presents a flexible and complete integration method for the digitally assisted workflow. The worker in the laboratory performs procedures in direct interaction with the digitized infrastructure that guides through the process and aids while performing tasks. The digital transformation of the laboratory starts with standardized integration of both new and "smart" lab devices, as well as legacy devices through a hardware gateway module. The open source Standardization in Lab Automation 2 standard is used for device communication. A central lab server channels all device communication and keeps a database record of every measurement, task and result generated or used in the lab. It acts as a central entry point for process management. This backbone enables a process control system to guide the worker through the lab process and provide additional assistance, like results of automated calculations or safety information. The description of the infrastructure and architecture is followed by a practical example on how to implement a digitized workflow. This approach is highly useful for - but not limited to - the biotechnological laboratory and has the potential to increase productivity in both industry and research for example by enabling automated documentation.
© 2020 The Authors. Engineering in Life Sciences published by Wiley‐VCH GmbH.

Entities:  

Keywords:  SiLA2; internet of things; laboratory device communication; laboratory digitization; laboratory network

Year:  2020        PMID: 33716619      PMCID: PMC7923558          DOI: 10.1002/elsc.202000053

Source DB:  PubMed          Journal:  Eng Life Sci        ISSN: 1618-0240            Impact factor:   2.678


  9 in total

1.  Lab automation and robotics: Automation on the move.

Authors:  Tim Chapman
Journal:  Nature       Date:  2003-02-06       Impact factor: 49.962

Review 2.  SiLA: Basic standards for rapid integration in laboratory automation.

Authors:  Henning Bär; Remo Hochstrasser; Bernd Papenfub
Journal:  J Lab Autom       Date:  2012-01-24

3.  Lab automation: tales along the road to automation.

Authors:  Nathan Blow
Journal:  Nat Methods       Date:  2008-01       Impact factor: 28.547

4.  Infoteam SiLA library simplifies device integration.

Authors:  Henning Bär; Uli Syré
Journal:  J Lab Autom       Date:  2011-06-29

5.  A scalable software framework for data integration in bioprocess development.

Authors:  Ingrid Schmid; Joachim Aschoff
Journal:  Eng Life Sci       Date:  2016-09-05       Impact factor: 2.678

Review 6.  The FAIR guiding principles for data stewardship: fair enough?

Authors:  Martin Boeckhout; Gerhard A Zielhuis; Annelien L Bredenoord
Journal:  Eur J Hum Genet       Date:  2018-05-17       Impact factor: 4.246

7.  Lab 4.0: SiLA or OPC UA.

Authors:  Günter Gauglitz
Journal:  Anal Bioanal Chem       Date:  2018-08       Impact factor: 4.142

8.  Introducing a Virtual Assistant to the Lab: A Voice User Interface for the Intuitive Control of Laboratory Instruments.

Authors:  Jonas Austerjost; Marc Porr; Noah Riedel; Dominik Geier; Thomas Becker; Thomas Scheper; Daniel Marquard; Patrick Lindner; Sascha Beutel
Journal:  SLAS Technol       Date:  2018-07-18       Impact factor: 3.047

9.  Clarity: an open-source manager for laboratory automation.

Authors:  Nigel F Delaney; José I Rojas Echenique; Christopher J Marx
Journal:  J Lab Autom       Date:  2012-10-02
  9 in total

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