Literature DB >> 33716137

Lysobisphosphatidic acid (LBPA) enrichment promotes cholesterol egress via exosomes in Niemann Pick type C1 deficient cells.

Olga Ilnytska1, Maciej Jeziorek2, Kimberly Lai3, Nihal Altan-Bonnet4, Radek Dobrowolski5, Judith Storch6.   

Abstract

Entities:  

Keywords:  Bis(monoacylglycero)phosphate; Cholesterol; Exosomes; Extracellular vesicles; Lysobisphosphatidic acid; Niemann-Pick C disease; Phosphatidylglycerol

Mesh：

Substances：

Year:  2021        PMID： 33716137      PMCID： PMC8038758          DOI： 10.1016/j.bbalip.2021.158916

Source DB:  PubMed          Journal:  Biochim Biophys Acta Mol Cell Biol Lipids        ISSN： 1388-1981            Impact factor:   5.228


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  21 in total

1.  Niemann Pick C2 protein enables cholesterol transfer from endo-lysosomes to the plasma membrane for efflux by shedding of extracellular vesicles.

Authors:  Alice Dupont Juhl; Frederik W Lund; Maria Louise V Jensen; Maria Szomek; Christian W Heegaard; Peter Guttmann; Stephan Werner; James McNally; Gerd Schneider; Sergey Kapishnikov; Daniel Wüstner
Journal:  Chem Phys Lipids       Date:  2021-01-07       Impact factor: 3.329

Review 2.  Cholesterol and the journey of extracellular vesicles.

Authors:  Frank W Pfrieger; Nicolas Vitale
Journal:  J Lipid Res       Date:  2018-04-20       Impact factor: 5.922

3.  Metabolism of phosphatidylglycerol and bis(monoacylglycero)-phosphate in macrophage subcellular fractions.

Authors:  M Waite; L King; T Thornburg; G Osthoff; T Y Thuren
Journal:  J Biol Chem       Date:  1990-12-15       Impact factor: 5.157

4.  Exosome secretion ameliorates lysosomal storage of cholesterol in Niemann-Pick type C disease.

Authors:  Katrin Strauss; Cornelia Goebel; Heiko Runz; Wiebke Möbius; Sievert Weiss; Ivo Feussner; Mikael Simons; Anja Schneider
Journal:  J Biol Chem       Date:  2010-06-16       Impact factor: 5.157

Review 5.  Niemann-Pick C2 (NPC2) and intracellular cholesterol trafficking.

Authors:  Judith Storch; Zhi Xu
Journal:  Biochim Biophys Acta       Date:  2009-02-13

6.  Cyclodextrin triggers MCOLN1-dependent endo-lysosome secretion in Niemann-Pick type C cells.

Authors:  Fabrizio Vacca; Stefania Vossio; Vincent Mercier; Dimitri Moreau; Shem Johnson; Cameron C Scott; Jonathan Paz Montoya; Marc Moniatte; Jean Gruenberg
Journal:  J Lipid Res       Date:  2019-02-01       Impact factor: 5.922

Review 7.  Niemann-Pick disease type C.

Authors:  Marie T Vanier
Journal:  Orphanet J Rare Dis       Date:  2010-06-03       Impact factor: 4.123

8.  Subcellular distributions of lipids in cultured BHK cells: evidence for the enrichment of lysobisphosphatidic acid and neutral lipids in lysosomes.

Authors:  J Brotherus; O Renkonen
Journal:  J Lipid Res       Date:  1977-03       Impact factor: 5.922

Review 9.  Miglustat in Niemann-Pick disease type C patients: a review.

Authors:  Mercè Pineda; Mark Walterfang; Marc C Patterson
Journal:  Orphanet J Rare Dis       Date:  2018-08-15       Impact factor: 4.123

10.  Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures.

Authors:  André M Miranda; Zofia M Lasiecka; Yimeng Xu; Jessi Neufeld; Sanjid Shahriar; Sabrina Simoes; Robin B Chan; Tiago Gil Oliveira; Scott A Small; Gilbert Di Paolo
Journal:  Nat Commun       Date:  2018-01-18       Impact factor: 14.919
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  3 in total

1.  Enrichment of NPC1-deficient cells with the lipid LBPA stimulates autophagy, improves lysosomal function, and reduces cholesterol storage.

Authors:  Olga Ilnytska; Kimberly Lai; Kirill Gorshkov; Mark L Schultz; Bruce Nguyen Tran; Maciej Jeziorek; Thaddeus J Kunkel; Ruth D Azaria; Hayley S McLoughlin; Miriam Waghalter; Yang Xu; Michael Schlame; Nihal Altan-Bonnet; Wei Zheng; Andrew P Lieberman; Radek Dobrowolski; Judith Storch
Journal:  J Biol Chem       Date:  2021-05-21       Impact factor: 5.157

Review 2.  Pathways and Mechanisms of Cellular Cholesterol Efflux-Insight From Imaging.

Authors:  Alice Dupont Juhl; Daniel Wüstner
Journal:  Front Cell Dev Biol       Date:  2022-03-01

Review 3.  Alterations in Lysosome Homeostasis in Lipid-Related Disorders: Impact on Metabolic Tissues and Immune Cells.

Authors:  Fernanda Cabrera-Reyes; Claudia Parra-Ruiz; María Isabel Yuseff; Silvana Zanlungo
Journal:  Front Cell Dev Biol       Date:  2021-12-10
  3 in total

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