Jia-Xing Zhang1, Juan Li1, Chen Chen1, Ting Yin1, Qing-An Wang1, Xiao-Xia Li1, Fa-Xuan Wang1, Jian-Hua Zhao2, Yi Zhao3, Yu-Hong Zhang4. 1. School of Public Health and Management, Ningxia Medical University, Ningxia Hui Autonomous Region, China. 2. The Ningxia Hui Autonomous Region Center for Disease Control and Prevention, Ningxia Hui Autonomous Region, China. 3. School of Public Health and Management, Ningxia Medical University, Ningxia Hui Autonomous Region, China. Electronic address: zhaoyi751114@hotmail.com. 4. School of Public Health and Management, Ningxia Medical University, Ningxia Hui Autonomous Region, China. Electronic address: zhabour@163.com.
Abstract
BACKGROUND: Skeletal muscle mass (SMM), fat mass (FM) and fat-to-muscle ratio (FMR) are significant indicators in epidemiology studies and clinical settings. The aim of this study was to establish age-related and sex-specific reference values for skeletal muscle mass index (SMMI), fat mass index (FMI) and FMR by bioelectrical impedance analysis (BIA) for healthy rural adults in western China. METHODS: This study is a cross-sectional study from Ningxia cohort study, included 13,790 individuals aged 35 to 74 years. Bioelectrical impedance analysis (BIA) was performed to measure body composition. Lambda-mu-sigma method was used to establish age-related and sex-specific percentile curves for SMMI, FMI and FMR. RESULTS: Overall, men had higher SMMI, but lower FMI and FMR than women for all ages. The SMMI decreased rapidly with age for men and women after 55 years and 45 years, respectively. FMI in men remain stable until 70 years; women's FMI showed a rapidly increasing after 50 years. The FMR increased consistently after 35 years for both men and women. These age-related and sex-specific reference values were established with the mean ± SD as the normal reference range. CONCLUSIONS: These reference values could be used as simple tools to identify age-specific low SMMI or high FMI and facilitate earlier identification sarcopenia or sarcopenic obesity in rural Chinese adults.
BACKGROUND: Skeletal muscle mass (SMM), fat mass (FM) and fat-to-muscle ratio (FMR) are significant indicators in epidemiology studies and clinical settings. The aim of this study was to establish age-related and sex-specific reference values for skeletal muscle mass index (SMMI), fat mass index (FMI) and FMR by bioelectrical impedance analysis (BIA) for healthy rural adults in western China. METHODS: This study is a cross-sectional study from Ningxia cohort study, included 13,790 individuals aged 35 to 74 years. Bioelectrical impedance analysis (BIA) was performed to measure body composition. Lambda-mu-sigma method was used to establish age-related and sex-specific percentile curves for SMMI, FMI and FMR. RESULTS: Overall, men had higher SMMI, but lower FMI and FMR than women for all ages. The SMMI decreased rapidly with age for men and women after 55 years and 45 years, respectively. FMI in men remain stable until 70 years; women's FMI showed a rapidly increasing after 50 years. The FMR increased consistently after 35 years for both men and women. These age-related and sex-specific reference values were established with the mean ± SD as the normal reference range. CONCLUSIONS: These reference values could be used as simple tools to identify age-specific low SMMI or high FMI and facilitate earlier identification sarcopenia or sarcopenic obesity in rural Chinese adults.
Authors: Thalwaththe Gedara Nadeeka Shayamalie Gunarathne; Li Yoong Tang; Soo Kun Lim; Nishantha Nanayakkara; Hewaratne Dassanayakege Wimala Thushari Damayanthi; Khatijah L Abdullah Journal: Int J Environ Res Public Health Date: 2022-05-03 Impact factor: 4.614