| Literature DB >> 3370995 |
S A Matlin1, R H Zhou, A Belenguer, R G Tyson, A N Brookes.
Abstract
Gossypol has been resolved into its pure optical isomers by conversion into the Schiff's base derivative of (+)-phenylalanine methyl ester, normal or reverse phase chromatography and hydrolysis. Forty grams of pure (-)-gossypol has been prepared in a micronised form for assessment of its antifertility and toxicological effects.Entities:
Keywords: Biology; Cancer; Clinical Research; Contraception; Contraception Research; Contraceptive Agents, Male; Contraceptive Agents--pharmacodynamics; Diseases; Family Planning; Genitalia; Germ Cells; Gossypol--pharmacodynamics; In Vitro; Male Contraception; Neoplasms; Physiology; Research Methodology; Spermatozoa; Urogenital System
Mesh：
Substances：
Year: 1988 PMID： 3370995 DOI： 10.1016/0010-7824(88)90025-x
Source DB: PubMed Journal: Contraception ISSN： 0010-7824 Impact factor: 3.375