OBJECTIVES: To explore the potential value of multiparametric magnetic resonance imaging (mpMRI) texture analysis (TA) to predict new Gleason Grade Group (GGG). METHODS: Fifty-eight lesions of fifty patients who underwent mpMRI scanning, including T2-weighted imaging (T2WI) and diffusion-weighted imaging (DWI) prior to trans-rectal ultrasound (TRUS)-guided core prostate biopsy, were retrospectively enrolled. TA parameters were obtained by the postprocessing software, and each lesion was assigned to its corresponding GGG. TA parameters derived from T2WI and DWI were statistically analyzed in detail. RESULTS: Energy, inertia, and correlation derived from apparent diffusion coefficient (ADC) maps and T2WI had a statistically significant difference among the five groups. Kurtosis, energy, inertia, correlation on ADC maps and Energy, inertia on T2WI were moderately related to the GGG trend. ADC-energy and T2-energy were significant independent predictors of the GGG trend. ADC-energy, T2WI-energy, and T2WI-correlation had a statistically significant difference between GGG1 and GGG2-5. ADC-energy were significant independent predictors of the GGG1. ADC-energy, T2WI-energy, and T2WI-correlation showed satisfactory diagnostic efficiency of GGG1 (area under the curve (AUC) 84.6, 74.3, and 83.5%, respectively), and ADC-energy showed excellent sensitivity and specificity (88.9 and 95.1%, respectively). CONCLUSION: TA parameters ADC-energy and T2-energy played an important role in predicting GGG trend. Both ADC-energy and T2-correlation produced a high diagnostic power of GGG1, and ADC-energy was perfect predictors of GGG1. ADVANCES IN KNOWLEDGE: TA parameters were innovatively used to predict new GGG trend, and the predictive factors of GGG1 were screen out.
OBJECTIVES: To explore the potential value of multiparametric magnetic resonance imaging (mpMRI) texture analysis (TA) to predict new Gleason Grade Group (GGG). METHODS: Fifty-eight lesions of fifty patients who underwent mpMRI scanning, including T2-weighted imaging (T2WI) and diffusion-weighted imaging (DWI) prior to trans-rectal ultrasound (TRUS)-guided core prostate biopsy, were retrospectively enrolled. TA parameters were obtained by the postprocessing software, and each lesion was assigned to its corresponding GGG. TA parameters derived from T2WI and DWI were statistically analyzed in detail. RESULTS: Energy, inertia, and correlation derived from apparent diffusion coefficient (ADC) maps and T2WI had a statistically significant difference among the five groups. Kurtosis, energy, inertia, correlation on ADC maps and Energy, inertia on T2WI were moderately related to the GGG trend. ADC-energy and T2-energy were significant independent predictors of the GGG trend. ADC-energy, T2WI-energy, and T2WI-correlation had a statistically significant difference between GGG1 and GGG2-5. ADC-energy were significant independent predictors of the GGG1. ADC-energy, T2WI-energy, and T2WI-correlation showed satisfactory diagnostic efficiency of GGG1 (area under the curve (AUC) 84.6, 74.3, and 83.5%, respectively), and ADC-energy showed excellent sensitivity and specificity (88.9 and 95.1%, respectively). CONCLUSION: TA parameters ADC-energy and T2-energy played an important role in predicting GGG trend. Both ADC-energy and T2-correlation produced a high diagnostic power of GGG1, and ADC-energy was perfect predictors of GGG1. ADVANCES IN KNOWLEDGE: TA parameters were innovatively used to predict new GGG trend, and the predictive factors of GGG1 were screen out.
Authors: A V D'Amico; R Whittington; S B Malkowicz; D Schultz; K Blank; G A Broderick; J E Tomaszewski; A A Renshaw; I Kaplan; C J Beard; A Wein Journal: JAMA Date: 1998-09-16 Impact factor: 56.272
Authors: Baris Turkbey; Andrew B Rosenkrantz; Masoom A Haider; Anwar R Padhani; Geert Villeirs; Katarzyna J Macura; Clare M Tempany; Peter L Choyke; Francois Cornud; Daniel J Margolis; Harriet C Thoeny; Sadhna Verma; Jelle Barentsz; Jeffrey C Weinreb Journal: Eur Urol Date: 2019-03-18 Impact factor: 20.096
Authors: Harbir S Sidhu; Salvatore Benigno; Balaji Ganeshan; Nikos Dikaios; Edward W Johnston; Clare Allen; Alex Kirkham; Ashley M Groves; Hashim U Ahmed; Mark Emberton; Stuart A Taylor; Steve Halligan; Shonit Punwani Journal: Eur Radiol Date: 2016-09-12 Impact factor: 5.315
Authors: Sohrab Afshari Mirak; Amirhossein Mohammadian Bajgiran; Kyunghyun Sung; Nazanin H Asvadi; Daniela Markovic; Ely R Felker; David Lu; Anthony Sisk; Robert E Reiter; Steven S Raman Journal: Abdom Radiol (NY) Date: 2020-07
Authors: Teodora Telecan; Iulia Andras; Nicolae Crisan; Lorin Giurgiu; Emanuel Darius Căta; Cosmin Caraiani; Andrei Lebovici; Bianca Boca; Zoltan Balint; Laura Diosan; Monica Lupsor-Platon Journal: J Pers Med Date: 2022-06-16