| Literature DB >> 33668215 |
Jiapei Yan1, Yeon Jeong Kim1, David E Somers1.
Abstract
The molecular components of the circadian system possess the interesting feature of acting together to create a self-sustaining oscillator, while at the same time acting individually, and in complexes, to confer phase-specific circadian control over a wide range of physiological and developmental outputs. This means that many circadian oscillator proteins are simultaneously also part of the circadian output pathway. Most studies have focused on transcriptional control of circadian rhythms, but work in plants and metazoans has shown the importance of post-transcriptional and post-translational processes within the circadian system. Here we highlight recent work describing post-translational mechanisms that impact both the function of the oscillator and the clock-controlled outputs.Entities:
Keywords: Arabidopsis; O-glycosylation; SUMOylation; circadian clock; intercellular/interorgan coupling; methylation; nucleocytoplasmic partitioning; phosphatidic acid; phosphorylation; ubiquitination
Mesh:
Substances:
Year: 2021 PMID: 33668215 PMCID: PMC7995963 DOI: 10.3390/genes12030325
Source DB: PubMed Journal: Genes (Basel) ISSN: 2073-4425 Impact factor: 4.096