Literature DB >> 33667223

Genome-wide association meta-analysis identifies pleiotropic risk loci for aerodigestive squamous cell cancers.

Corina Lesseur1,2, Aida Ferreiro-Iglesias1, James D McKay3, Yohan Bossé4, Mattias Johansson1, Valerie Gaborieau1, Maria Teresa Landi5, David C Christiani6, Neil C Caporaso5, Stig E Bojesen7, Christopher I Amos8, Sanjay Shete9, Geoffrey Liu10, Gadi Rennert11, Demetrius Albanes5, Melinda C Aldrich12, Adonina Tardon13, Chu Chen14, Liloglou Triantafillos15, John K Field15, Marion Dawn Teare16, Lambertus A Kiemeney17, Brenda Diergaarde18,19,20, Robert L Ferris20, Shanbeh Zienolddiny21, Stephen Lam22, Andrew F Olshan23, Mark C Weissler24, Martin Lacko25, Angela Risch26,27,28, Heike Bickeböller29, Andy R Ness30,31, Steve Thomas31, Loic Le Marchand32, Matthew B Schabath33, Victor Wünsch-Filho34, Eloiza H Tajara35, Angeline S Andrew36, Gary M Clifford37, Philip Lazarus38, Kjell Grankvist39, Mikael Johansson40, Susanne Arnold41, Olle Melander42,43, Hans Brunnström44, Stefania Boccia45,46, Gabriella Cadoni47,48, Wim Timens49,50, Ma'en Obeidat51, Xiangjun Xiao8, Richard S Houlston52, Rayjean J Hung53, Paul Brennan1.   

Abstract

Squamous cell carcinomas (SqCC) of the aerodigestive tract have similar etiological risk factors. Although genetic risk variants for individual cancers have been identified, an agnostic, genome-wide search for shared genetic susceptibility has not been performed. To identify novel and pleotropic SqCC risk variants, we performed a meta-analysis of GWAS data on lung SqCC (LuSqCC), oro/pharyngeal SqCC (OSqCC), laryngeal SqCC (LaSqCC) and esophageal SqCC (ESqCC) cancers, totaling 13,887 cases and 61,961 controls of European ancestry. We identified one novel genome-wide significant (Pmeta<5x10-8) aerodigestive SqCC susceptibility loci in the 2q33.1 region (rs56321285, TMEM273). Additionally, three previously unknown loci reached suggestive significance (Pmeta<5x10-7): 1q32.1 (rs12133735, near MDM4), 5q31.2 (rs13181561, TMEM173) and 19p13.11 (rs61494113, ABHD8). Multiple previously identified loci for aerodigestive SqCC also showed evidence of pleiotropy in at least another SqCC site, these include: 4q23 (ADH1B), 6p21.33 (STK19), 6p21.32 (HLA-DQB1), 9p21.33 (CDKN2B-AS1) and 13q13.1(BRCA2). Gene-based association and gene set enrichment identified a set of 48 SqCC-related genes rel to DNA damage and epigenetic regulation pathways. Our study highlights the importance of cross-cancer analyses to identify pleiotropic risk loci of histology-related cancers arising at distinct anatomical sites.

Entities:  

Mesh：

Substances：

Year:  2021        PMID： 33667223      PMCID： PMC7968735          DOI： 10.1371/journal.pgen.1009254

Source DB:  PubMed          Journal:  PLoS Genet        ISSN： 1553-7390            Impact factor:   5.917


  62 in total

Review 1.  Squamous Cell Cancers: A Unified Perspective on Biology and Genetics.

Authors:  G Paolo Dotto; Anil K Rustgi
Journal:  Cancer Cell       Date:  2016-05-09       Impact factor: 31.743

2.  Modifying effect of MDM4 variants on risk of HPV16-associated squamous cell carcinoma of oropharynx.

Authors:  Hongping Yu; Erich M Sturgis; Zhensheng Liu; Li-E Wang; Qingyi Wei; Guojun Li
Journal:  Cancer       Date:  2011-08-05       Impact factor: 6.860

3.  Next-generation genotype imputation service and methods.

Authors:  Sayantan Das; Lukas Forer; Sebastian Schönherr; Carlo Sidore; Adam E Locke; Alan Kwong; Scott I Vrieze; Emily Y Chew; Shawn Levy; Matt McGue; David Schlessinger; Dwight Stambolian; Po-Ru Loh; William G Iacono; Anand Swaroop; Laura J Scott; Francesco Cucca; Florian Kronenberg; Michael Boehnke; Gonçalo R Abecasis; Christian Fuchsberger
Journal:  Nat Genet       Date:  2016-08-29       Impact factor: 38.330

4.  KEGG as a reference resource for gene and protein annotation.

Authors:  Minoru Kanehisa; Yoko Sato; Masayuki Kawashima; Miho Furumichi; Mao Tanabe
Journal:  Nucleic Acids Res       Date:  2015-10-17       Impact factor: 16.971

5.  Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

Authors:  James D McKay; Rayjean J Hung; Younghun Han; Xuchen Zong; Robert Carreras-Torres; David C Christiani; Neil E Caporaso; Mattias Johansson; Xiangjun Xiao; Yafang Li; Jinyoung Byun; Alison Dunning; Karen A Pooley; David C Qian; Xuemei Ji; Geoffrey Liu; Maria N Timofeeva; Stig E Bojesen; Xifeng Wu; Loic Le Marchand; Demetrios Albanes; Heike Bickeböller; Melinda C Aldrich; William S Bush; Adonina Tardon; Gad Rennert; M Dawn Teare; John K Field; Lambertus A Kiemeney; Philip Lazarus; Aage Haugen; Stephen Lam; Matthew B Schabath; Angeline S Andrew; Hongbing Shen; Yun-Chul Hong; Jian-Min Yuan; Pier Alberto Bertazzi; Angela C Pesatori; Yuanqing Ye; Nancy Diao; Li Su; Ruyang Zhang; Yonathan Brhane; Natasha Leighl; Jakob S Johansen; Anders Mellemgaard; Walid Saliba; Christopher A Haiman; Lynne R Wilkens; Ana Fernandez-Somoano; Guillermo Fernandez-Tardon; Henricus F M van der Heijden; Jin Hee Kim; Juncheng Dai; Zhibin Hu; Michael P A Davies; Michael W Marcus; Hans Brunnström; Jonas Manjer; Olle Melander; David C Muller; Kim Overvad; Antonia Trichopoulou; Rosario Tumino; Jennifer A Doherty; Matt P Barnett; Chu Chen; Gary E Goodman; Angela Cox; Fiona Taylor; Penella Woll; Irene Brüske; H-Erich Wichmann; Judith Manz; Thomas R Muley; Angela Risch; Albert Rosenberger; Kjell Grankvist; Mikael Johansson; Frances A Shepherd; Ming-Sound Tsao; Susanne M Arnold; Eric B Haura; Ciprian Bolca; Ivana Holcatova; Vladimir Janout; Milica Kontic; Jolanta Lissowska; Anush Mukeria; Simona Ognjanovic; Tadeusz M Orlowski; Ghislaine Scelo; Beata Swiatkowska; David Zaridze; Per Bakke; Vidar Skaug; Shanbeh Zienolddiny; Eric J Duell; Lesley M Butler; Woon-Puay Koh; Yu-Tang Gao; Richard S Houlston; John McLaughlin; Victoria L Stevens; Philippe Joubert; Maxime Lamontagne; David C Nickle; Ma'en Obeidat; Wim Timens; Bin Zhu; Lei Song; Linda Kachuri; María Soler Artigas; Martin D Tobin; Louise V Wain; Thorunn Rafnar; Thorgeir E Thorgeirsson; Gunnar W Reginsson; Kari Stefansson; Dana B Hancock; Laura J Bierut; Margaret R Spitz; Nathan C Gaddis; Sharon M Lutz; Fangyi Gu; Eric O Johnson; Ahsan Kamal; Claudio Pikielny; Dakai Zhu; Sara Lindströem; Xia Jiang; Rachel F Tyndale; Georgia Chenevix-Trench; Jonathan Beesley; Yohan Bossé; Stephen Chanock; Paul Brennan; Maria Teresa Landi; Christopher I Amos
Journal:  Nat Genet       Date:  2017-06-12       Impact factor: 38.330

6.  Genome-wide association studies identify four ER negative-specific breast cancer risk loci.

Authors:  Montserrat Garcia-Closas; Fergus J Couch; Sara Lindstrom; Kyriaki Michailidou; Marjanka K Schmidt; Mark N Brook; Nick Orr; Suhn Kyong Rhie; Elio Riboli; Heather S Feigelson; Loic Le Marchand; Julie E Buring; Diana Eccles; Penelope Miron; Peter A Fasching; Hiltrud Brauch; Jenny Chang-Claude; Jane Carpenter; Andrew K Godwin; Heli Nevanlinna; Graham G Giles; Angela Cox; John L Hopper; Manjeet K Bolla; Qin Wang; Joe Dennis; Ed Dicks; Will J Howat; Nils Schoof; Stig E Bojesen; Diether Lambrechts; Annegien Broeks; Irene L Andrulis; Pascal Guénel; Barbara Burwinkel; Elinor J Sawyer; Antoinette Hollestelle; Olivia Fletcher; Robert Winqvist; Hermann Brenner; Arto Mannermaa; Ute Hamann; Alfons Meindl; Annika Lindblom; Wei Zheng; Peter Devillee; Mark S Goldberg; Jan Lubinski; Vessela Kristensen; Anthony Swerdlow; Hoda Anton-Culver; Thilo Dörk; Kenneth Muir; Keitaro Matsuo; Anna H Wu; Paolo Radice; Soo Hwang Teo; Xiao-Ou Shu; William Blot; Daehee Kang; Mikael Hartman; Suleeporn Sangrajrang; Chen-Yang Shen; Melissa C Southey; Daniel J Park; Fleur Hammet; Jennifer Stone; Laura J Van't Veer; Emiel J Rutgers; Artitaya Lophatananon; Sarah Stewart-Brown; Pornthep Siriwanarangsan; Julian Peto; Michael G Schrauder; Arif B Ekici; Matthias W Beckmann; Isabel Dos Santos Silva; Nichola Johnson; Helen Warren; Ian Tomlinson; Michael J Kerin; Nicola Miller; Federick Marme; Andreas Schneeweiss; Christof Sohn; Therese Truong; Pierre Laurent-Puig; Pierre Kerbrat; Børge G Nordestgaard; Sune F Nielsen; Henrik Flyger; Roger L Milne; Jose Ignacio Arias Perez; Primitiva Menéndez; Heiko Müller; Volker Arndt; Christa Stegmaier; Peter Lichtner; Magdalena Lochmann; Christina Justenhoven; Yon-Dschun Ko; Taru A Muranen; Kristiina Aittomäki; Carl Blomqvist; Dario Greco; Tuomas Heikkinen; Hidemi Ito; Hiroji Iwata; Yasushi Yatabe; Natalia N Antonenkova; Sara Margolin; Vesa Kataja; Veli-Matti Kosma; Jaana M Hartikainen; Rosemary Balleine; Chiu-Chen Tseng; David Van Den Berg; Daniel O Stram; Patrick Neven; Anne-Sophie Dieudonné; Karin Leunen; Anja Rudolph; Stefan Nickels; Dieter Flesch-Janys; Paolo Peterlongo; Bernard Peissel; Loris Bernard; Janet E Olson; Xianshu Wang; Kristen Stevens; Gianluca Severi; Laura Baglietto; Catriona McLean; Gerhard A Coetzee; Ye Feng; Brian E Henderson; Fredrick Schumacher; Natalia V Bogdanova; France Labrèche; Martine Dumont; Cheng Har Yip; Nur Aishah Mohd Taib; Ching-Yu Cheng; Martha Shrubsole; Jirong Long; Katri Pylkäs; Arja Jukkola-Vuorinen; Saila Kauppila; Julia A Knight; Gord Glendon; Anna Marie Mulligan; Robertus A E M Tollenaar; Caroline M Seynaeve; Mieke Kriege; Maartje J Hooning; Ans M W van den Ouweland; Carolien H M van Deurzen; Wei Lu; Yu-Tang Gao; Hui Cai; Sabapathy P Balasubramanian; Simon S Cross; Malcolm W R Reed; Lisa Signorello; Qiuyin Cai; Mitul Shah; Hui Miao; Ching Wan Chan; Kee Seng Chia; Anna Jakubowska; Katarzyna Jaworska; Katarzyna Durda; Chia-Ni Hsiung; Pei-Ei Wu; Jyh-Cherng Yu; Alan Ashworth; Michael Jones; Daniel C Tessier; Anna González-Neira; Guillermo Pita; M Rosario Alonso; Daniel Vincent; Francois Bacot; Christine B Ambrosone; Elisa V Bandera; Esther M John; Gary K Chen; Jennifer J Hu; Jorge L Rodriguez-Gil; Leslie Bernstein; Michael F Press; Regina G Ziegler; Robert M Millikan; Sandra L Deming-Halverson; Sarah Nyante; Sue A Ingles; Quinten Waisfisz; Helen Tsimiklis; Enes Makalic; Daniel Schmidt; Minh Bui; Lorna Gibson; Bertram Müller-Myhsok; Rita K Schmutzler; Rebecca Hein; Norbert Dahmen; Lars Beckmann; Kirsimari Aaltonen; Kamila Czene; Astrid Irwanto; Jianjun Liu; Clare Turnbull; Nazneen Rahman; Hanne Meijers-Heijboer; Andre G Uitterlinden; Fernando Rivadeneira; Curtis Olswold; Susan Slager; Robert Pilarski; Foluso Ademuyiwa; Irene Konstantopoulou; Nicholas G Martin; Grant W Montgomery; Dennis J Slamon; Claudia Rauh; Michael P Lux; Sebastian M Jud; Thomas Bruning; Joellen Weaver; Priyanka Sharma; Harsh Pathak; Will Tapper; Sue Gerty; Lorraine Durcan; Dimitrios Trichopoulos; Rosario Tumino; Petra H Peeters; Rudolf Kaaks; Daniele Campa; Federico Canzian; Elisabete Weiderpass; Mattias Johansson; Kay-Tee Khaw; Ruth Travis; Françoise Clavel-Chapelon; Laurence N Kolonel; Constance Chen; Andy Beck; Susan E Hankinson; Christine D Berg; Robert N Hoover; Jolanta Lissowska; Jonine D Figueroa; Daniel I Chasman; Mia M Gaudet; W Ryan Diver; Walter C Willett; David J Hunter; Jacques Simard; Javier Benitez; Alison M Dunning; Mark E Sherman; Georgia Chenevix-Trench; Stephen J Chanock; Per Hall; Paul D P Pharoah; Celine Vachon; Douglas F Easton; Christopher A Haiman; Peter Kraft
Journal:  Nat Genet       Date:  2013-04       Impact factor: 38.330

7.  Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer.

Authors:  Fergus J Couch; Karoline B Kuchenbaecker; Kyriaki Michailidou; Gustavo A Mendoza-Fandino; Silje Nord; Janna Lilyquist; Curtis Olswold; Emily Hallberg; Simona Agata; Habibul Ahsan; Kristiina Aittomäki; Christine Ambrosone; Irene L Andrulis; Hoda Anton-Culver; Volker Arndt; Banu K Arun; Brita Arver; Monica Barile; Rosa B Barkardottir; Daniel Barrowdale; Lars Beckmann; Matthias W Beckmann; Javier Benitez; Stephanie V Blank; Carl Blomqvist; Natalia V Bogdanova; Stig E Bojesen; Manjeet K Bolla; Bernardo Bonanni; Hiltrud Brauch; Hermann Brenner; Barbara Burwinkel; Saundra S Buys; Trinidad Caldes; Maria A Caligo; Federico Canzian; Jane Carpenter; Jenny Chang-Claude; Stephen J Chanock; Wendy K Chung; Kathleen B M Claes; Angela Cox; Simon S Cross; Julie M Cunningham; Kamila Czene; Mary B Daly; Francesca Damiola; Hatef Darabi; Miguel de la Hoya; Peter Devilee; Orland Diez; Yuan C Ding; Riccardo Dolcetti; Susan M Domchek; Cecilia M Dorfling; Isabel Dos-Santos-Silva; Martine Dumont; Alison M Dunning; Diana M Eccles; Hans Ehrencrona; Arif B Ekici; Heather Eliassen; Steve Ellis; Peter A Fasching; Jonine Figueroa; Dieter Flesch-Janys; Asta Försti; Florentia Fostira; William D Foulkes; Tara Friebel; Eitan Friedman; Debra Frost; Marike Gabrielson; Marilie D Gammon; Patricia A Ganz; Susan M Gapstur; Judy Garber; Mia M Gaudet; Simon A Gayther; Anne-Marie Gerdes; Maya Ghoussaini; Graham G Giles; Gord Glendon; Andrew K Godwin; Mark S Goldberg; David E Goldgar; Anna González-Neira; Mark H Greene; Jacek Gronwald; Pascal Guénel; Marc Gunter; Lothar Haeberle; Christopher A Haiman; Ute Hamann; Thomas V O Hansen; Steven Hart; Sue Healey; Tuomas Heikkinen; Brian E Henderson; Josef Herzog; Frans B L Hogervorst; Antoinette Hollestelle; Maartje J Hooning; Robert N Hoover; John L Hopper; Keith Humphreys; David J Hunter; Tomasz Huzarski; Evgeny N Imyanitov; Claudine Isaacs; Anna Jakubowska; Paul James; Ramunas Janavicius; Uffe Birk Jensen; Esther M John; Michael Jones; Maria Kabisch; Siddhartha Kar; Beth Y Karlan; Sofia Khan; Kay-Tee Khaw; Muhammad G Kibriya; Julia A Knight; Yon-Dschun Ko; Irene Konstantopoulou; Veli-Matti Kosma; Vessela Kristensen; Ava Kwong; Yael Laitman; Diether Lambrechts; Conxi Lazaro; Eunjung Lee; Loic Le Marchand; Jenny Lester; Annika Lindblom; Noralane Lindor; Sara Lindstrom; Jianjun Liu; Jirong Long; Jan Lubinski; Phuong L Mai; Enes Makalic; Kathleen E Malone; Arto Mannermaa; Siranoush Manoukian; Sara Margolin; Frederik Marme; John W M Martens; Lesley McGuffog; Alfons Meindl; Austin Miller; Roger L Milne; Penelope Miron; Marco Montagna; Sylvie Mazoyer; Anna M Mulligan; Taru A Muranen; Katherine L Nathanson; Susan L Neuhausen; Heli Nevanlinna; Børge G Nordestgaard; Robert L Nussbaum; Kenneth Offit; Edith Olah; Olufunmilayo I Olopade; Janet E Olson; Ana Osorio; Sue K Park; Petra H Peeters; Bernard Peissel; Paolo Peterlongo; Julian Peto; Catherine M Phelan; Robert Pilarski; Bruce Poppe; Katri Pylkäs; Paolo Radice; Nazneen Rahman; Johanna Rantala; Christine Rappaport; Gad Rennert; Andrea Richardson; Mark Robson; Isabelle Romieu; Anja Rudolph; Emiel J Rutgers; Maria-Jose Sanchez; Regina M Santella; Elinor J Sawyer; Daniel F Schmidt; Marjanka K Schmidt; Rita K Schmutzler; Fredrick Schumacher; Rodney Scott; Leigha Senter; Priyanka Sharma; Jacques Simard; Christian F Singer; Olga M Sinilnikova; Penny Soucy; Melissa Southey; Doris Steinemann; Marie Stenmark-Askmalm; Dominique Stoppa-Lyonnet; Anthony Swerdlow; Csilla I Szabo; Rulla Tamimi; William Tapper; Manuel R Teixeira; Soo-Hwang Teo; Mary B Terry; Mads Thomassen; Deborah Thompson; Laima Tihomirova; Amanda E Toland; Robert A E M Tollenaar; Ian Tomlinson; Thérèse Truong; Helen Tsimiklis; Alex Teulé; Rosario Tumino; Nadine Tung; Clare Turnbull; Giski Ursin; Carolien H M van Deurzen; Elizabeth J van Rensburg; Raymonda Varon-Mateeva; Zhaoming Wang; Shan Wang-Gohrke; Elisabete Weiderpass; Jeffrey N Weitzel; Alice Whittemore; Hans Wildiers; Robert Winqvist; Xiaohong R Yang; Drakoulis Yannoukakos; Song Yao; M Pilar Zamora; Wei Zheng; Per Hall; Peter Kraft; Celine Vachon; Susan Slager; Georgia Chenevix-Trench; Paul D P Pharoah; Alvaro A N Monteiro; Montserrat García-Closas; Douglas F Easton; Antonis C Antoniou
Journal:  Nat Commun       Date:  2016-04-27       Impact factor: 14.919

8.  Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity.

Authors:  Aida Ferreiro-Iglesias; Corina Lesseur; James McKay; Rayjean J Hung; Younghun Han; Xuchen Zong; David Christiani; Mattias Johansson; Xiangjun Xiao; Yafang Li; David C Qian; Xuemei Ji; Geoffrey Liu; Neil Caporaso; Ghislaine Scelo; David Zaridze; Anush Mukeriya; Milica Kontic; Simona Ognjanovic; Jolanta Lissowska; Małgorzata Szołkowska; Beata Swiatkowska; Vladimir Janout; Ivana Holcatova; Ciprian Bolca; Milan Savic; Miodrag Ognjanovic; Stig Egil Bojesen; Xifeng Wu; Demetrios Albanes; Melinda C Aldrich; Adonina Tardon; Ana Fernandez-Somoano; Guillermo Fernandez-Tardon; Loic Le Marchand; Gadi Rennert; Chu Chen; Jennifer Doherty; Gary Goodman; Heike Bickeböller; H-Erich Wichmann; Angela Risch; Albert Rosenberger; Hongbing Shen; Juncheng Dai; John K Field; Michael Davies; Penella Woll; M Dawn Teare; Lambertus A Kiemeney; Erik H F M van der Heijden; Jian-Min Yuan; Yun-Chul Hong; Aage Haugen; Shanbeh Zienolddiny; Stephen Lam; Ming-Sound Tsao; Mikael Johansson; Kjell Grankvist; Matthew B Schabath; Angeline Andrew; Eric Duell; Olle Melander; Hans Brunnström; Philip Lazarus; Susanne Arnold; Stacey Slone; Jinyoung Byun; Ahsan Kamal; Dakai Zhu; Maria Teresa Landi; Christopher I Amos; Paul Brennan
Journal:  Nat Commun       Date:  2018-09-25       Impact factor: 14.919

9.  Shared heritability and functional enrichment across six solid cancers.

Authors:  Xia Jiang; Hilary K Finucane; Fredrick R Schumacher; Stephanie L Schmit; Jonathan P Tyrer; Younghun Han; Kyriaki Michailidou; Corina Lesseur; Karoline B Kuchenbaecker; Joe Dennis; David V Conti; Graham Casey; Mia M Gaudet; Jeroen R Huyghe; Demetrius Albanes; Melinda C Aldrich; Angeline S Andrew; Irene L Andrulis; Hoda Anton-Culver; Antonis C Antoniou; Natalia N Antonenkova; Susanne M Arnold; Kristan J Aronson; Banu K Arun; Elisa V Bandera; Rosa B Barkardottir; Daniel R Barnes; Jyotsna Batra; Matthias W Beckmann; Javier Benitez; Sara Benlloch; Andrew Berchuck; Sonja I Berndt; Heike Bickeböller; Stephanie A Bien; Carl Blomqvist; Stefania Boccia; Natalia V Bogdanova; Stig E Bojesen; Manjeet K Bolla; Hiltrud Brauch; Hermann Brenner; James D Brenton; Mark N Brook; Joan Brunet; Hans Brunnström; Daniel D Buchanan; Barbara Burwinkel; Ralf Butzow; Gabriella Cadoni; Trinidad Caldés; Maria A Caligo; Ian Campbell; Peter T Campbell; Géraldine Cancel-Tassin; Lisa Cannon-Albright; Daniele Campa; Neil Caporaso; André L Carvalho; Andrew T Chan; Jenny Chang-Claude; Stephen J Chanock; Chu Chen; David C Christiani; Kathleen B M Claes; Frank Claessens; Judith Clements; J Margriet Collée; Marcia Cruz Correa; Fergus J Couch; Angela Cox; Julie M Cunningham; Cezary Cybulski; Kamila Czene; Mary B Daly; Anna deFazio; Peter Devilee; Orland Diez; Manuela Gago-Dominguez; Jenny L Donovan; Thilo Dörk; Eric J Duell; Alison M Dunning; Miriam Dwek; Diana M Eccles; Christopher K Edlund; Digna R Velez Edwards; Carolina Ellberg; D Gareth Evans; Peter A Fasching; Robert L Ferris; Triantafillos Liloglou; Jane C Figueiredo; Olivia Fletcher; Renée T Fortner; Florentia Fostira; Silvia Franceschi; Eitan Friedman; Steven J Gallinger; Patricia A Ganz; Judy Garber; José A García-Sáenz; Simon A Gayther; Graham G Giles; Andrew K Godwin; Mark S Goldberg; David E Goldgar; Ellen L Goode; Marc T Goodman; Gary Goodman; Kjell Grankvist; Mark H Greene; Henrik Gronberg; Jacek Gronwald; Pascal Guénel; Niclas Håkansson; Per Hall; Ute Hamann; Freddie C Hamdy; Robert J Hamilton; Jochen Hampe; Aage Haugen; Florian Heitz; Rolando Herrero; Peter Hillemanns; Michael Hoffmeister; Estrid Høgdall; Yun-Chul Hong; John L Hopper; Richard Houlston; Peter J Hulick; David J Hunter; David G Huntsman; Gregory Idos; Evgeny N Imyanitov; Sue Ann Ingles; Claudine Isaacs; Anna Jakubowska; Paul James; Mark A Jenkins; Mattias Johansson; Mikael Johansson; Esther M John; Amit D Joshi; Radka Kaneva; Beth Y Karlan; Linda E Kelemen; Tabea Kühl; Kay-Tee Khaw; Elza Khusnutdinova; Adam S Kibel; Lambertus A Kiemeney; Jeri Kim; Susanne K Kjaer; Julia A Knight; Manolis Kogevinas; Zsofia Kote-Jarai; Stella Koutros; Vessela N Kristensen; Jolanta Kupryjanczyk; Martin Lacko; Stephan Lam; Diether Lambrechts; Maria Teresa Landi; Philip Lazarus; Nhu D Le; Eunjung Lee; Flavio Lejbkowicz; Heinz-Josef Lenz; Goska Leslie; Davor Lessel; Jenny Lester; Douglas A Levine; Li Li; Christopher I Li; Annika Lindblom; Noralane M Lindor; Geoffrey Liu; Fotios Loupakis; Jan Lubiński; Lovise Maehle; Christiane Maier; Arto Mannermaa; Loic Le Marchand; Sara Margolin; Taymaa May; Lesley McGuffog; Alfons Meindl; Pooja Middha; Austin Miller; Roger L Milne; Robert J MacInnis; Francesmary Modugno; Marco Montagna; Victor Moreno; Kirsten B Moysich; Lorelei Mucci; Kenneth Muir; Anna Marie Mulligan; Katherine L Nathanson; David E Neal; Andrew R Ness; Susan L Neuhausen; Heli Nevanlinna; Polly A Newcomb; Lisa F Newcomb; Finn Cilius Nielsen; Liene Nikitina-Zake; Børge G Nordestgaard; Robert L Nussbaum; Kenneth Offit; Edith Olah; Ali Amin Al Olama; Olufunmilayo I Olopade; Andrew F Olshan; Håkan Olsson; Ana Osorio; Hardev Pandha; Jong Y Park; Nora Pashayan; Michael T Parsons; Tanja Pejovic; Kathryn L Penney; Wilbert H M Peters; Catherine M Phelan; Amanda I Phipps; Dijana Plaseska-Karanfilska; Miranda Pring; Darya Prokofyeva; Paolo Radice; Kari Stefansson; Susan J Ramus; Leon Raskin; Gad Rennert; Hedy S Rennert; Elizabeth J van Rensburg; Marjorie J Riggan; Harvey A Risch; Angela Risch; Monique J Roobol; Barry S Rosenstein; Mary Anne Rossing; Kim De Ruyck; Emmanouil Saloustros; Dale P Sandler; Elinor J Sawyer; Matthew B Schabath; Johanna Schleutker; Marjanka K Schmidt; V Wendy Setiawan; Hongbing Shen; Erin M Siegel; Weiva Sieh; Christian F Singer; Martha L Slattery; Karina Dalsgaard Sorensen; Melissa C Southey; Amanda B Spurdle; Janet L Stanford; Victoria L Stevens; Sebastian Stintzing; Jennifer Stone; Karin Sundfeldt; Rebecca Sutphen; Anthony J Swerdlow; Eloiza H Tajara; Catherine M Tangen; Adonina Tardon; Jack A Taylor; M Dawn Teare; Manuel R Teixeira; Mary Beth Terry; Kathryn L Terry; Stephen N Thibodeau; Mads Thomassen; Line Bjørge; Marc Tischkowitz; Amanda E Toland; Diana Torres; Paul A Townsend; Ruth C Travis; Nadine Tung; Shelley S Tworoger; Cornelia M Ulrich; Nawaid Usmani; Celine M Vachon; Els Van Nieuwenhuysen; Ana Vega; Miguel Elías Aguado-Barrera; Qin Wang; Penelope M Webb; Clarice R Weinberg; Stephanie Weinstein; Mark C Weissler; Jeffrey N Weitzel; Catharine M L West; Emily White; Alice S Whittemore; H-Erich Wichmann; Fredrik Wiklund; Robert Winqvist; Alicja Wolk; Penella Woll; Michael Woods; Anna H Wu; Xifeng Wu; Drakoulis Yannoukakos; Wei Zheng; Shanbeh Zienolddiny; Argyrios Ziogas; Kristin K Zorn; Jacqueline M Lane; Richa Saxena; Duncan Thomas; Rayjean J Hung; Brenda Diergaarde; James McKay; Ulrike Peters; Li Hsu; Montserrat García-Closas; Rosalind A Eeles; Georgia Chenevix-Trench; Paul J Brennan; Christopher A Haiman; Jacques Simard; Douglas F Easton; Stephen B Gruber; Paul D P Pharoah; Alkes L Price; Bogdan Pasaniuc; Christopher I Amos; Peter Kraft; Sara Lindström
Journal:  Nat Commun       Date:  2019-01-25       Impact factor: 17.694

Review 10.  The long and the short of it: the MDM4 tail so far.

Authors:  Sue Haupt; Javier Octavio Mejía-Hernández; Reshma Vijayakumaran; Simon P Keam; Ygal Haupt
Journal:  J Mol Cell Biol       Date:  2019-03-01       Impact factor: 6.216
View more
  3 in total

1.  Common variants in breast cancer risk loci predispose to distinct tumor subtypes.

Authors:  Thomas U Ahearn; Haoyu Zhang; Montserrat García-Closas; Nilanjan Chatterjee; Kyriaki Michailidou; Roger L Milne; Manjeet K Bolla; Joe Dennis; Alison M Dunning; Michael Lush; Qin Wang; Irene L Andrulis; Hoda Anton-Culver; Volker Arndt; Kristan J Aronson; Paul L Auer; Annelie Augustinsson; Adinda Baten; Heiko Becher; Sabine Behrens; Javier Benitez; Marina Bermisheva; Carl Blomqvist; Stig E Bojesen; Bernardo Bonanni; Anne-Lise Børresen-Dale; Hiltrud Brauch; Hermann Brenner; Angela Brooks-Wilson; Thomas Brüning; Barbara Burwinkel; Saundra S Buys; Federico Canzian; Jose E Castelao; Jenny Chang-Claude; Stephen J Chanock; Georgia Chenevix-Trench; Christine L Clarke; J Margriet Collée; Angela Cox; Simon S Cross; Kamila Czene; Mary B Daly; Peter Devilee; Thilo Dörk; Miriam Dwek; Diana M Eccles; D Gareth Evans; Peter A Fasching; Jonine Figueroa; Giuseppe Floris; Manuela Gago-Dominguez; Susan M Gapstur; José A García-Sáenz; Mia M Gaudet; Graham G Giles; Mark S Goldberg; Anna González-Neira; Grethe I Grenaker Alnæs; Mervi Grip; Pascal Guénel; Christopher A Haiman; Per Hall; Ute Hamann; Elaine F Harkness; Bernadette A M Heemskerk-Gerritsen; Bernd Holleczek; Antoinette Hollestelle; Maartje J Hooning; Robert N Hoover; John L Hopper; Anthony Howell; Milena Jakimovska; Anna Jakubowska; Esther M John; Michael E Jones; Audrey Jung; Rudolf Kaaks; Saila Kauppila; Renske Keeman; Elza Khusnutdinova; Cari M Kitahara; Yon-Dschun Ko; Stella Koutros; Vessela N Kristensen; Ute Krüger; Katerina Kubelka-Sabit; Allison W Kurian; Kyriacos Kyriacou; Diether Lambrechts; Derrick G Lee; Annika Lindblom; Martha Linet; Jolanta Lissowska; Ana Llaneza; Wing-Yee Lo; Robert J MacInnis; Arto Mannermaa; Mehdi Manoochehri; Sara Margolin; Maria Elena Martinez; Catriona McLean; Alfons Meindl; Usha Menon; Heli Nevanlinna; William G Newman; Jesse Nodora; Kenneth Offit; Håkan Olsson; Nick Orr; Tjoung-Won Park-Simon; Alpa V Patel; Julian Peto; Guillermo Pita; Dijana Plaseska-Karanfilska; Ross Prentice; Kevin Punie; Katri Pylkäs; Paolo Radice; Gad Rennert; Atocha Romero; Thomas Rüdiger; Emmanouil Saloustros; Sarah Sampson; Dale P Sandler; Elinor J Sawyer; Rita K Schmutzler; Minouk J Schoemaker; Ben Schöttker; Mark E Sherman; Xiao-Ou Shu; Snezhana Smichkoska; Melissa C Southey; John J Spinelli; Anthony J Swerdlow; Rulla M Tamimi; William J Tapper; Jack A Taylor; Lauren R Teras; Mary Beth Terry; Diana Torres; Melissa A Troester; Celine M Vachon; Carolien H M van Deurzen; Elke M van Veen; Philippe Wagner; Clarice R Weinberg; Camilla Wendt; Jelle Wesseling; Robert Winqvist; Alicja Wolk; Xiaohong R Yang; Wei Zheng; Fergus J Couch; Jacques Simard; Peter Kraft; Douglas F Easton; Paul D P Pharoah; Marjanka K Schmidt
Journal:  Breast Cancer Res       Date:  2022-01-04       Impact factor: 8.408

2.  Genetic Analysis of Lung Cancer and the Germline Impact on Somatic Mutation Burden.

Authors:  Aurélie A G Gabriel; Joshua R Atkins; Ricardo C C Penha; Karl Smith-Byrne; Valerie Gaborieau; Catherine Voegele; Behnoush Abedi-Ardekani; Maja Milojevic; Robert Olaso; Vincent Meyer; Anne Boland; Jean François Deleuze; David Zaridze; Anush Mukeriya; Beata Swiatkowska; Vladimir Janout; Miriam Schejbalová; Dana Mates; Jelena Stojšić; Miodrag Ognjanovic; John S Witte; Sara R Rashkin; Linda Kachuri; Rayjean J Hung; Siddhartha Kar; Paul Brennan; Anne-Sophie Sertier; Anthony Ferrari; Alain Viari; Mattias Johansson; Christopher I Amos; Matthieu Foll; James D McKay
Journal:  J Natl Cancer Inst       Date:  2022-08-08       Impact factor: 11.816

Review 3.  Approach to Localized Squamous Cell Cancer of the Esophagus.

Authors:  Chloe Weidenbaum; Michael K Gibson
Journal:  Curr Treat Options Oncol       Date:  2022-08-31
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.