Literature DB >> 33661944

Study on mechanical properties and permeability of elliptical porous scaffold based on the SLM manufactured medical Ti6Al4V.

Chenglong Shi1, Nana Lu1, Yaru Qin1, Mingdi Liu1,2, Hongxia Li1, Haichao Li1.   

Abstract

In this paper, we take the elliptical pore structure which is similar to the microstructure of cancellous bone as the research object, four groups of bone scaffolds were designed from the perspective of pore size, porosity and pore distribution. The size of the all scaffolds were uniformly designed as 10 × 10 × 12 mm. Four groups of model samples were prepared by selective laser melting (SLM) and Ti6Al4V materials. The statics performance of the scaffolds was comprehensively evaluated by mechanical compression simulation and mechanical compression test, the manufacturing error of the scaffold samples were evaluated by scanning electron microscope (SEM), and the permeability of the scaffolds were predicted and evaluated by simulation analysis of computational fluid dynamics (CFD). The results show that the different distribution of porosity, pore size and pores of the elliptical scaffold have a certain influence on the mechanical properties and permeability of the scaffold, and the reasonable size and angle distribution of the elliptical pore can match the mechanical properties and permeability of the elliptical pore scaffold with human cancellous bone, which has great potential for research and application in the field of artificial bone scaffold.

Entities:  

Year:  2021        PMID: 33661944      PMCID: PMC7932120          DOI: 10.1371/journal.pone.0247764

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


  20 in total

1.  Porosity of human mandibular condylar bone.

Authors:  G A P Renders; L Mulder; L J van Ruijven; T M G J van Eijden
Journal:  J Anat       Date:  2007-03       Impact factor: 2.610

2.  Finite element study of scaffold architecture design and culture conditions for tissue engineering.

Authors:  Andy L Olivares; Elia Marsal; Josep A Planell; Damien Lacroix
Journal:  Biomaterials       Date:  2009-08-11       Impact factor: 12.479

3.  Permeability study of cancellous bone and its idealised structures.

Authors:  Ardiyansyah Syahrom; Mohammed Rafiq Abdul Kadir; Muhamad Nor Harun; Andreas Öchsner
Journal:  Med Eng Phys       Date:  2014-12-16       Impact factor: 2.242

4.  The inter-sample structural variability of regular tissue-engineered scaffolds significantly affects the micromechanical local cell environment.

Authors:  A Campos Marin; D Lacroix
Journal:  Interface Focus       Date:  2015-04-06       Impact factor: 3.906

5.  Design and properties of 3D scaffolds for bone tissue engineering.

Authors:  S Gómez; M D Vlad; J López; E Fernández
Journal:  Acta Biomater       Date:  2016-06-28       Impact factor: 8.947

6.  Biological and mechanical property analysis for designed heterogeneous porous scaffolds based on the refined TPMS.

Authors:  Songhua Ma; Kaile Song; Jing Lan; Li Ma
Journal:  J Mech Behav Biomed Mater       Date:  2020-03-23

7.  Mechanical performance of highly permeable laser melted Ti6Al4V bone scaffolds.

Authors:  Arun Arjunan; Marios Demetriou; Ahmad Baroutaji; Chang Wang
Journal:  J Mech Behav Biomed Mater       Date:  2019-11-06

8.  Tailored mechanical response and mass transport characteristic of selective laser melted porous metallic biomaterials for bone scaffolds.

Authors:  Lei Zhang; Bo Song; Lei Yang; Yusheng Shi
Journal:  Acta Biomater       Date:  2020-06-03       Impact factor: 8.947

9.  Characterization of the structure and permeability of titanium foams for spinal fusion devices.

Authors:  R Singh; P D Lee; Trevor C Lindley; R J Dashwood; Emilie Ferrie; T Imwinkelried
Journal:  Acta Biomater       Date:  2008-07-01       Impact factor: 8.947

10.  3D Printing Bioceramic Porous Scaffolds with Good Mechanical Property and Cell Affinity.

Authors:  Chih-Hao Chang; Chih-Yang Lin; Fwu-Hsing Liu; Mark Hung-Chih Chen; Chun-Pin Lin; Hong-Nerng Ho; Yunn-Shiuan Liao
Journal:  PLoS One       Date:  2015-11-30       Impact factor: 3.240

View more
  3 in total

1.  Ti64/20Ag Porous Composites Fabricated by Powder Metallurgy for Biomedical Applications.

Authors:  Luis Olmos; Ana S Gonzaléz-Pedraza; Héctor J Vergara-Hernández; Jorge Chávez; Omar Jimenez; Elena Mihalcea; Dante Arteaga; José J Ruiz-Mondragón
Journal:  Materials (Basel)       Date:  2022-08-29       Impact factor: 3.748

2.  Optimization of Structural and Processing Parameters for Selective Laser Melting of Porous 316L Bone Scaffolds.

Authors:  Shubo Xu; Sen Zhang; Guocheng Ren; Yuefei Pan; Jianing Li
Journal:  Materials (Basel)       Date:  2022-08-26       Impact factor: 3.748

Review 3.  Application of Computational Method in Designing a Unit Cell of Bone Tissue Engineering Scaffold: A Review.

Authors:  Nur Syahirah Mustafa; Nor Hasrul Akhmal; Sudin Izman; Mat Hussin Ab Talib; Ashrul Ishak Mohamad Shaiful; Mohd Nazri Bin Omar; Nor Zaiazmin Yahaya; Suhaimi Illias
Journal:  Polymers (Basel)       Date:  2021-05-14       Impact factor: 4.329

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.