Literature DB >> 33635890

A natural language processing and deep learning approach to identify child abuse from pediatric electronic medical records.

Akshaya V Annapragada1, Marcella M Donaruma-Kwoh2, Ananth V Annapragada3,4, Zbigniew A Starosolski3,4.   

Abstract

Child physical abuse is a leading cause of traumatic injury and death in children. In 2017, child abuse was responsible for 1688 fatalities in the United States, of 3.5 million children referred to Child Protection Services and 674,000 substantiated victims. While large referral hospitals maintain teams trained in Child Abuse Pediatrics, smaller community hospitals often do not have such dedicated resources to evaluate patients for potential abuse. Moreover, identification of abuse has a low margin of error, as false positive identifications lead to unwarranted separations, while false negatives allow dangerous situations to continue. This context makes the consistent detection of and response to abuse difficult, particularly given subtle signs in young, non-verbal patients. Here, we describe the development of artificial intelligence algorithms that use unstructured free-text in the electronic medical record-including notes from physicians, nurses, and social workers-to identify children who are suspected victims of physical abuse. Importantly, only the notes from time of first encounter (e.g.: birth, routine visit, sickness) to the last record before child protection team involvement were used. This allowed us to develop an algorithm using only information available prior to referral to the specialized child protection team. The study was performed in a multi-center referral pediatric hospital on patients screened for abuse within five different locations between 2015 and 2019. Of 1123 patients, 867 records were available after data cleaning and processing, and 55% were abuse-positive as determined by a multi-disciplinary team of clinical professionals. These electronic medical records were encoded with three natural language processing (NLP) algorithms-Bag of Words (BOW), Word Embeddings (WE), and Rules-Based (RB)-and used to train multiple neural network architectures. The BOW and WE encodings utilize the full free-text, while RB selects crucial phrases as identified by physicians. The best architecture was selected by average classification accuracy for the best performing model from each train-test split of a cross-validation experiment. Natural language processing coupled with neural networks detected cases of likely child abuse using only information available to clinicians prior to child protection team referral with average accuracy of 0.90±0.02 and average area under the receiver operator characteristic curve (ROC-AUC) 0.93±0.02 for the best performing Bag of Words models. The best performing rules-based models achieved average accuracy of 0.77±0.04 and average ROC-AUC 0.81±0.05, while a Word Embeddings strategy was severely limited by lack of representative embeddings. Importantly, the best performing model had a false positive rate of 8%, as compared to rates of 20% or higher in previously reported studies. This artificial intelligence approach can help screen patients for whom an abuse concern exists and streamline the identification of patients who may benefit from referral to a child protection team. Furthermore, this approach could be applied to develop computer-aided-diagnosis platforms for the challenging and often intractable problem of reliably identifying pediatric patients suffering from physical abuse.

Entities:  

Year:  2021        PMID: 33635890      PMCID: PMC7909689          DOI: 10.1371/journal.pone.0247404

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


  20 in total

1.  Use of natural language processing in electronic medical records to identify pregnant women with suicidal behavior: towards a solution to the complex classification problem.

Authors:  Qiu-Yue Zhong; Leena P Mittal; Margo D Nathan; Kara M Brown; Deborah Knudson González; Tianrun Cai; Sean Finan; Bizu Gelaye; Paul Avillach; Jordan W Smoller; Elizabeth W Karlson; Tianxi Cai; Michelle A Williams
Journal:  Eur J Epidemiol       Date:  2018-12-10       Impact factor: 8.082

2.  Validation of a clinical prediction rule for pediatric abusive head trauma.

Authors:  Kent P Hymel; Veronica Armijo-Garcia; Robin Foster; Terra N Frazier; Michael Stoiko; LeeAnn M Christie; Nancy S Harper; Kerri Weeks; Christopher L Carroll; Phil Hyden; Andrew Sirotnak; Edward Truemper; Amy E Ornstein; Ming Wang
Journal:  Pediatrics       Date:  2014-11-17       Impact factor: 7.124

3.  Natural language processing of symptoms documented in free-text narratives of electronic health records: a systematic review.

Authors:  Theresa A Koleck; Caitlin Dreisbach; Philip E Bourne; Suzanne Bakken
Journal:  J Am Med Inform Assoc       Date:  2019-04-01       Impact factor: 4.497

4.  Prevalence and Correlates of the Co-Occurrence of Family Violence: A Meta-Analysis on Family Polyvictimization.

Authors:  Ko Ling Chan; Qiqi Chen; Mengtong Chen
Journal:  Trauma Violence Abuse       Date:  2019-05-08

5.  Validation of the Pittsburgh Infant Brain Injury Score for Abusive Head Trauma.

Authors:  Rachel Pardes Berger; Janet Fromkin; Bruce Herman; Mary Clyde Pierce; Richard A Saladino; Lynda Flom; Elizabeth C Tyler-Kabara; Tom McGinn; Rudolph Richichi; Patrick M Kochanek
Journal:  Pediatrics       Date:  2016-06-23       Impact factor: 7.124

6.  Deep Patient: An Unsupervised Representation to Predict the Future of Patients from the Electronic Health Records.

Authors:  Riccardo Miotto; Li Li; Brian A Kidd; Joel T Dudley
Journal:  Sci Rep       Date:  2016-05-17       Impact factor: 4.379

7.  Clinical text classification with rule-based features and knowledge-guided convolutional neural networks.

Authors:  Liang Yao; Chengsheng Mao; Yuan Luo
Journal:  BMC Med Inform Decis Mak       Date:  2019-04-04       Impact factor: 2.796

8.  Validation of a Prediction Tool for Abusive Head Trauma.

Authors:  Laura Elizabeth Cowley; Charlotte Bethan Morris; Sabine Ann Maguire; Daniel Mark Farewell; Alison Mary Kemp
Journal:  Pediatrics       Date:  2015-08       Impact factor: 7.124

9.  Efficient prediction of drug-drug interaction using deep learning models.

Authors:  Prashant Kumar Shukla; Piyush Kumar Shukla; Poonam Sharma; Paresh Rawat; Jashwant Samar; Rahul Moriwal; Manjit Kaur
Journal:  IET Syst Biol       Date:  2020-08       Impact factor: 1.615

10.  MIMIC-III, a freely accessible critical care database.

Authors:  Alistair E W Johnson; Tom J Pollard; Lu Shen; Li-Wei H Lehman; Mengling Feng; Mohammad Ghassemi; Benjamin Moody; Peter Szolovits; Leo Anthony Celi; Roger G Mark
Journal:  Sci Data       Date:  2016-05-24       Impact factor: 6.444

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  3 in total

1.  Developing machine learning-based models to help identify child abuse and neglect: key ethical challenges and recommended solutions.

Authors:  Aviv Y Landau; Susi Ferrarello; Ashley Blanchard; Kenrick Cato; Nia Atkins; Stephanie Salazar; Desmond U Patton; Maxim Topaz
Journal:  J Am Med Inform Assoc       Date:  2022-01-29       Impact factor: 4.497

2.  Considerations for development of child abuse and neglect phenotype with implications for reduction of racial bias: a qualitative study.

Authors:  Aviv Y Landau; Ashley Blanchard; Kenrick Cato; Nia Atkins; Stephanie Salazar; Desmond U Patton; Maxim Topaz
Journal:  J Am Med Inform Assoc       Date:  2022-01-29       Impact factor: 4.497

Review 3.  Technology-Based Mental Health Interventions for Domestic Violence Victims Amid COVID-19.

Authors:  Zhaohui Su; Ali Cheshmehzangi; Dean McDonnell; Hengcai Chen; Junaid Ahmad; Sabina Šegalo; Claudimar Pereira da Veiga
Journal:  Int J Environ Res Public Health       Date:  2022-04-03       Impact factor: 3.390

  3 in total

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