Taylor Estes Gin1, Erin Lashnits1, James M Wilson2, Edward B Breitschwerdt3, Barbara Qurollo1. 1. Department of Clinical sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, United States. 2. Vector-Borne Disease Diagnostic Lab, North Carolina State University, Raleigh, North Carolina, United States. 3. Internal Medicine, North Carolina State University, Raleigh, North Carolina, United States.
Abstract
BACKGROUND: Leishmania infantum infections are reported in foxhounds throughout the United States (US) and Canada, but only rarely in other dog breeds. A seroprevalence report from 2006 documented leishmaniosis in foxhounds (8.9%) tested in the US between 2000 and 2003. All other breeds were seronegative. OBJECTIVE: To reexamine demographics and travel history of L. infantum-infected dogs in the US and Canada, we hypothesize detection of L. infantum in more foxhounds than nonfoxhounds and that infected nonfoxhounds will have traveled to endemic regions. ANIMALS: A total of 125 dogs positive for L. infantum by immunofluorescent antibody, PCR, or both. METHODS: Retrospective, descriptive study of L. infantum-infected dogs between 4 January 2006 and 22 May 2019. Travel history and known lineage to foxhounds was collected from questionnaires. RESULTS: Leishmania infantum was detected in 125 (6.4%) of 1961 dogs tested between 4 January 2006 and 22 May 2019, of which 10 (8%) were foxhounds and 115 (92%) were nonfoxhound breeds. Travel history available for 69 (55%) dogs showed 60 (86.9%) dogs had traveled outside of the US or Canada. Nine (13%) dogs had not traveled outside of the US or Canada, 5 of which were nonfoxhounds. CONCLUSIONS AND CLINICAL IMPORTANCE: The majority of L. infantum cases were detected in nonfoxhounds, many of which had traveled to L. infantum-endemic countries, and several nonfoxhound breeds had no travel history. Leishmania surveillance should be considered for dogs that return from L. infantum-endemic regions to monitor emergence of this zoonotic disease in the US and Canada.
BACKGROUND:Leishmania infantum infections are reported in foxhounds throughout the United States (US) and Canada, but only rarely in other dog breeds. A seroprevalence report from 2006 documented leishmaniosis in foxhounds (8.9%) tested in the US between 2000 and 2003. All other breeds were seronegative. OBJECTIVE: To reexamine demographics and travel history of L. infantum-infecteddogs in the US and Canada, we hypothesize detection of L. infantum in more foxhounds than nonfoxhounds and that infected nonfoxhounds will have traveled to endemic regions. ANIMALS: A total of 125 dogs positive for L. infantum by immunofluorescent antibody, PCR, or both. METHODS: Retrospective, descriptive study of L. infantum-infecteddogs between 4 January 2006 and 22 May 2019. Travel history and known lineage to foxhounds was collected from questionnaires. RESULTS:Leishmania infantum was detected in 125 (6.4%) of 1961 dogs tested between 4 January 2006 and 22 May 2019, of which 10 (8%) were foxhounds and 115 (92%) were nonfoxhound breeds. Travel history available for 69 (55%) dogs showed 60 (86.9%) dogs had traveled outside of the US or Canada. Nine (13%) dogs had not traveled outside of the US or Canada, 5 of which were nonfoxhounds. CONCLUSIONS AND CLINICAL IMPORTANCE: The majority of L. infantum cases were detected in nonfoxhounds, many of which had traveled to L. infantum-endemic countries, and several nonfoxhound breeds had no travel history. Leishmania surveillance should be considered for dogs that return from L. infantum-endemic regions to monitor emergence of this zoonotic disease in the US and Canada.
Authors: Peter M Schantz; Francis J Steurer; Zandra H Duprey; Katherine P Kurpel; Stephen C Barr; Joan E Jackson; Edward B Breitschwerdt; Michael G Levy; J C Fox Journal: J Am Vet Med Assoc Date: 2005-04-15 Impact factor: 1.936
Authors: Amanda A Gaskin; Peter Schantz; Joan Jackson; Adam Birkenheuer; Lindsay Tomlinson; Marina Gramiccia; Michael Levy; Frank Steurer; Eleanor Kollmar; Barbara C Hegarty; Albert Ahn; Edward B Breitschwerdt Journal: J Vet Intern Med Date: 2002 Jan-Feb Impact factor: 3.333
Authors: Katrin Kuhls; Mohammad Zahangir Alam; Elisa Cupolillo; Gabriel Eduardo M Ferreira; Isabel L Mauricio; Rolando Oddone; M Dora Feliciangeli; Thierry Wirth; Michael A Miles; Gabriele Schönian Journal: PLoS Negl Trop Dis Date: 2011-06-07
Authors: Taylor Estes Gin; Erin Lashnits; James M Wilson; Edward B Breitschwerdt; Barbara Qurollo Journal: J Vet Intern Med Date: 2021-02-26 Impact factor: 3.333
Authors: Taylor Estes Gin; Erin Lashnits; James M Wilson; Edward B Breitschwerdt; Barbara Qurollo Journal: J Vet Intern Med Date: 2021-02-26 Impact factor: 3.333