Literature DB >> 33633316

Airborne dispersion of droplets during coughing: a physical model of viral transmission.

Hongying Li1, Fong Yew Leong2, George Xu1, Chang Wei Kang1, Keng Hui Lim1, Ban Hock Tan3, Chian Min Loo4.   

Abstract

The Covid-19 pandemic has focused attention on airborne transmission of viruses. Using realistic air flow simulation, we model droplet dispersion from coughing and study the transmission risk related to SARS-CoV-2. Although this model defines most airborne droplets as 8-16 µm in diameter, we infer that larger droplets of 32-40 µm in diameter may potentially be more infectious due to higher viral content. Use of face masks is therefore recommended for both personal and social protection. We found social distancing effective at reducing transmission potential across all droplet sizes. However, the presence of a human body 1 m away modifies the aerodynamics so that downstream droplet dispersion is enhanced, which has implications on safe distancing in queues. At 1 m distance, we found that an average of 0.55 viral copies is inhaled for a cough at median loading, scalable up to 340 copies at peak loading. Droplet evaporation results in significant reduction in droplet counts, but airborne transmission remains possible even under low humidity conditions.

Entities:  

Year:  2021        PMID: 33633316      PMCID: PMC7907382          DOI: 10.1038/s41598-021-84245-2

Source DB:  PubMed          Journal:  Sci Rep        ISSN: 2045-2322            Impact factor:   4.379


  47 in total

Review 1.  Aerosol deposition in health and disease.

Authors:  Chantal Darquenne
Journal:  J Aerosol Med Pulm Drug Deliv       Date:  2012-06       Impact factor: 2.849

2.  Turbulent Gas Clouds and Respiratory Pathogen Emissions: Potential Implications for Reducing Transmission of COVID-19.

Authors:  Lydia Bourouiba
Journal:  JAMA       Date:  2020-05-12       Impact factor: 56.272

3.  High SARS-CoV-2 Attack Rate Following Exposure at a Choir Practice - Skagit County, Washington, March 2020.

Authors:  Lea Hamner; Polly Dubbel; Ian Capron; Andy Ross; Amber Jordan; Jaxon Lee; Joanne Lynn; Amelia Ball; Simranjit Narwal; Sam Russell; Dale Patrick; Howard Leibrand
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2020-05-15       Impact factor: 17.586

4.  Exposure to influenza virus aerosols during routine patient care.

Authors:  Werner E Bischoff; Katrina Swett; Iris Leng; Timothy R Peters
Journal:  J Infect Dis       Date:  2013-01-30       Impact factor: 5.226

5.  Flow dynamics and characterization of a cough.

Authors:  J K Gupta; C-H Lin; Q Chen
Journal:  Indoor Air       Date:  2009-07-31       Impact factor: 5.770

6.  Aerosol and Surface Distribution of Severe Acute Respiratory Syndrome Coronavirus 2 in Hospital Wards, Wuhan, China, 2020.

Authors:  Zhen-Dong Guo; Zhong-Yi Wang; Shou-Feng Zhang; Xiao Li; Lin Li; Chao Li; Yan Cui; Rui-Bin Fu; Yun-Zhu Dong; Xiang-Yang Chi; Meng-Yao Zhang; Kun Liu; Cheng Cao; Bin Liu; Ke Zhang; Yu-Wei Gao; Bing Lu; Wei Chen
Journal:  Emerg Infect Dis       Date:  2020-06-21       Impact factor: 6.883

7.  On coughing and airborne droplet transmission to humans.

Authors:  Talib Dbouk; Dimitris Drikakis
Journal:  Phys Fluids (1994)       Date:  2020-05-01       Impact factor: 3.521

8.  Simulation suggests that rapid activation of social distancing can arrest epidemic development due to a novel strain of influenza.

Authors:  Joel K Kelso; George J Milne; Heath Kelly
Journal:  BMC Public Health       Date:  2009-04-29       Impact factor: 3.295

Review 9.  Recognition of aerosol transmission of infectious agents: a commentary.

Authors:  Raymond Tellier; Yuguo Li; Benjamin J Cowling; Julian W Tang
Journal:  BMC Infect Dis       Date:  2019-01-31       Impact factor: 3.090

View more
  6 in total

Review 1.  Innate Receptors Expression by Lung Nociceptors: Impact on COVID-19 and Aging.

Authors:  Carlos H Hiroki; Nicole Sarden; Mortaza F Hassanabad; Bryan G Yipp
Journal:  Front Immunol       Date:  2021-12-16       Impact factor: 7.561

2.  Spread of infectious agents through the air in complex spaces.

Authors:  Ian Eames; Jan-Bert Flór
Journal:  Interface Focus       Date:  2022-02-11       Impact factor: 3.906

3.  Computational decision-support tools for urban design to improve resilience against COVID-19 and other infectious diseases: A systematic review.

Authors:  Liu Yang; Michiyo Iwami; Yishan Chen; Mingbo Wu; Koen H van Dam
Journal:  Prog Plann       Date:  2022-03-09

4.  Mitigating COVID-19 infection disease transmission in indoor environment using physical barriers.

Authors:  Chen Ren; Chang Xi; Junqi Wang; Zhuangbo Feng; Fuzhan Nasiri; Shi-Jie Cao; Fariborz Haghighat
Journal:  Sustain Cities Soc       Date:  2021-07-14       Impact factor: 7.587

5.  Inactivation of Enveloped Bovine Viral Diarrhea Virus and Non-Enveloped Porcine Parvovirus Using Low-Pressure Non-Thermal Plasma.

Authors:  Florian Le Bras; Gaëlle Carré; Yasmina Aguemon; Marius Colin; Marie-Paule Gellé
Journal:  Life (Basel)       Date:  2021-11-24

6.  Droplet nuclei caustic formations in exhaled vortex rings.

Authors:  Andreas Papoutsakis; Ionut Danaila; Francky Luddens; Manolis Gavaises
Journal:  Sci Rep       Date:  2022-03-10       Impact factor: 4.379

  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.