Cristiano Sconza1,2, Giacomo Braghetto3,4,5, Stefano Respizzi1,2, Emanuela Morenghi1,2, Elizaveta Kon1,2,6, Berardo Di Matteo1,2. 1. Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20090, Italy. 2. IRCCS Humanitas Resarch Hospital, Via Manzoni 56, Rozzano, 20089, Italy. 3. Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20090, Italy. braghetto-400782@asst-monza.it. 4. IRCCS Humanitas Resarch Hospital, Via Manzoni 56, Rozzano, 20089, Italy. braghetto-400782@asst-monza.it. 5. ASST Monza - Ospedale San Gerardo, Via Pergolesi, 33, Monza, Italy. braghetto-400782@asst-monza.it. 6. First Moscow State Medical University - Sechenov University, Moscow, Russia.
Abstract
BACKGROUND: The social impact and economic burden of low back pain are well known among the medical community. A novel therapeutic approach is represented by oxygen-ozone therapy, whose anti-inflammatory effects could be especially useful in patients with herniated discs. The most common administration is through a palpation-guided injection technique, although the use of ultrasound guidance could allow a more precise delivery of the therapeutic substance close to the nerve root. AIM OF THE STUDY: To describe the clinical outcomes following US-guided periradicular injection of oxygen-ozone as a treatment option for low back pain associated to sciatica in patients affected by symptomatic L5-S1 disc herniation. CONCLUSION: Ultrasound-guided periradicular injection of oxygen-ozone in L5-S1 herniation is a safe and effective minimally invasive treatment, able to improve both low back and radiating pain.
BACKGROUND: The social impact and economic burden of low back pain are well known among the medical community. A novel therapeutic approach is represented by oxygen-ozone therapy, whose anti-inflammatory effects could be especially useful in patients with herniated discs. The most common administration is through a palpation-guided injection technique, although the use of ultrasound guidance could allow a more precise delivery of the therapeutic substance close to the nerve root. AIM OF THE STUDY: To describe the clinical outcomes following US-guided periradicular injection of oxygen-ozone as a treatment option for low back pain associated to sciatica in patients affected by symptomatic L5-S1 disc herniation. CONCLUSION: Ultrasound-guided periradicular injection of oxygen-ozone in L5-S1 herniation is a safe and effective minimally invasive treatment, able to improve both low back and radiating pain.
Authors: Cosma F Andreula; Luigi Simonetti; Fabio De Santis; Raffaele Agati; Renata Ricci; Marco Leonardi Journal: AJNR Am J Neuroradiol Date: 2003-05 Impact factor: 3.825
Authors: Alessandro de Sire; Nicola Marotta; Martina Ferrillo; Francesco Agostini; Cristiano Sconza; Lorenzo Lippi; Stefano Respizzi; Amerigo Giudice; Marco Invernizzi; Antonio Ammendolia Journal: Int J Mol Sci Date: 2022-02-25 Impact factor: 5.923