Literature DB >> 33627704

The comparison of pancreatic and hepatic steatosis in healthy liver donor candidates.

Bedriye Koyuncu Sokmen1, Tolga Sahin2, Alihan Oral3, Erdem Kocak2, Nagihan Inan4.   

Abstract

The aim of this study was to investigate the relationship between nonalcoholic fatty liver disease (NAFLD) and pancreatic steatosis (PS) in patients with biopsy-proven NAFLD. 228 patients with biopsy-proven NAFLD patients who admitted to the Faculty of Medicine of Demiroglu Bilim University between 2004 and 2019 were included in the study. Demographic, laboratory, histological and radiological findings of the patients were recorded retrospectively. Hepatosteatosis (HS) levels were measured by both CT and biopsy, while PS levels were measured by 3 different CT-based techniques. 89 (39%) of the patients were female and 139 (61%) were male. The mean body mass index (BMI) was 27.2 ± 4.0. Biochemical parameters were within normal limits. Liver biopsy showed a significant correlation with HS grade on CT scan (p < 0.001). When CT findings were compared, a significant correlation was found between PS and HS (p < 0.05), but there was no correlation between the HS level in biopsy and the pancreatic adiposity on CT (p > 0.05). Our study was the first to compare biopsy-proven NAFLD and PS, and no correlation was found between biopsy-proven NAFLD and PS.

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Year:  2021        PMID: 33627704      PMCID: PMC7904852          DOI: 10.1038/s41598-021-83871-0

Source DB:  PubMed          Journal:  Sci Rep        ISSN: 2045-2322            Impact factor:   4.379


  37 in total

1.  Nonalcoholic fatty liver disease is related to nonalcoholic fatty pancreas disease.

Authors:  Erwin-Jan M van Geenen; Mark M Smits; Tim C M A Schreuder; Donald L van der Peet; Elisabeth Bloemena; Chris J J Mulder
Journal:  Pancreas       Date:  2010-11       Impact factor: 3.327

Review 2.  The clinical significance of pancreatic steatosis.

Authors:  Mark M Smits; Erwin J M van Geenen
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2011-02-08       Impact factor: 46.802

Review 3.  Nonalcoholic Fatty Pancreas Disease.

Authors:  Nihar Shah; Jason P Rocha; Neal Bhutiani; Omer Endashaw
Journal:  Nutr Clin Pract       Date:  2019-10       Impact factor: 3.080

4.  Associated factors for a hyperechogenic pancreas on endoscopic ultrasound.

Authors:  Cheol Woong Choi; Gwang Ha Kim; Dae Hwan Kang; Hyung Wook Kim; Dong Uk Kim; Jeong Heo; Geun Am Song; Do Youn Park; Suk Kim
Journal:  World J Gastroenterol       Date:  2010-09-14       Impact factor: 5.742

Review 5.  Non-alcoholic fatty pancreas disease - practices for clinicians.

Authors:  Larisa Pinte; Daniel Vasile Balaban; Cristian Băicuş; Mariana Jinga
Journal:  Rom J Intern Med       Date:  2019-09-01

Review 6.  Biomarkers in nonalcoholic fatty liver disease.

Authors:  Manuela G Neuman; Lawrence B Cohen; Radu M Nanau
Journal:  Can J Gastroenterol Hepatol       Date:  2014-12

7.  MRI-determined fat content of human liver, pancreas and kidney.

Authors:  Paul E Sijens; Mireille A Edens; Stephan J L Bakker; Ronald P Stolk
Journal:  World J Gastroenterol       Date:  2010-04-28       Impact factor: 5.742

8.  Clinical implications of fatty pancreas: correlations between fatty pancreas and metabolic syndrome.

Authors:  Jun Seok Lee; Sang Heum Kim; Dae Won Jun; Jee Hye Han; Eun Chul Jang; Ji Young Park; Byung Kwan Son; Seong Hwan Kim; Yoon Ju Jo; Young Sook Park; Yong Soo Kim
Journal:  World J Gastroenterol       Date:  2009-04-21       Impact factor: 5.742

9.  Lipomatosis of the pancreas in autopsy material and its relation to age and overweight.

Authors:  T S Olsen
Journal:  Acta Pathol Microbiol Scand A       Date:  1978-09

10.  Macrovesicular hepatic steatosis in living related liver donors: correlation between CT and histologic findings.

Authors:  Piyaporn Limanond; Steven S Raman; Charles Lassman; James Sayre; R Mark Ghobrial; Ronald W Busuttil; Sammy Saab; David S K Lu
Journal:  Radiology       Date:  2004-01       Impact factor: 11.105

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  1 in total

1.  Combined effect of pancreatic lipid content and gene variants (TCF7L2, WFS1 and 11BHSD1) on B-cell function in Middle Aged Women in a Post Hoc Analysis.

Authors:  Ákos Nádasdi; Viktor Gál; Tamás Masszi; Attila Patócs; Peter Igaz; Anikó Somogyi; Gábor Firneisz
Journal:  Diabetol Metab Syndr       Date:  2022-07-27       Impact factor: 5.395

  1 in total

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