Literature DB >> 33624095

Utility of a safety switch to abrogate CD19.CAR T-cell-associated neurotoxicity.

Matthew C Foster1,2, Barbara Savoldo2,3,4, Winnie Lau5, Clio Rubinos5, Natalie Grover1,2, Paul Armistead1,2, James Coghill1,2, Robert S Hagan1,6, Kaitlin Morrison2, Faith Brianne Buchanan1,2, Catherine Cheng2, Spencer Laing2, Anastasia Ivanova2,7, John West2, Aaron Foster8, Jonathan Serody1,2,4, Gianpietro Dotti2,4.   

Abstract

Entities:  

Keywords:  B-ALL; CD19 CAR T cells; ICANS; IMMUNOBIOLOGY, Cytotoxic T cells; NEOPLASIA, Lymphoid Leukemias: Immunotherapeutic approaches; inducible Caspase 9; safety switch

Mesh:

Substances:

Year:  2021        PMID: 33624095      PMCID: PMC8351894          DOI: 10.1182/blood.2021010784

Source DB:  PubMed          Journal:  Blood        ISSN: 0006-4971            Impact factor:   25.476


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  14 in total

1.  Tisagenlecleucel in Adult Relapsed or Refractory Diffuse Large B-Cell Lymphoma.

Authors:  Stephen J Schuster; Michael R Bishop; Constantine S Tam; Edmund K Waller; Peter Borchmann; Joseph P McGuirk; Ulrich Jäger; Samantha Jaglowski; Charalambos Andreadis; Jason R Westin; Isabelle Fleury; Veronika Bachanova; S Ronan Foley; P Joy Ho; Stephan Mielke; John M Magenau; Harald Holte; Serafino Pantano; Lida B Pacaud; Rakesh Awasthi; Jufen Chu; Özlem Anak; Gilles Salles; Richard T Maziarz
Journal:  N Engl J Med       Date:  2018-12-01       Impact factor: 91.245

2.  Clinical and Biological Correlates of Neurotoxicity Associated with CAR T-cell Therapy in Patients with B-cell Acute Lymphoblastic Leukemia.

Authors:  Bianca D Santomasso; Jae H Park; Darin Salloum; Isabelle Riviere; Jessica Flynn; Elena Mead; Elizabeth Halton; Xiuyan Wang; Brigitte Senechal; Terence Purdon; Justin R Cross; Hui Liu; Behroze Vachha; Xi Chen; Lisa M DeAngelis; Daniel Li; Yvette Bernal; Mithat Gonen; Hans-Guido Wendel; Michel Sadelain; Renier J Brentjens
Journal:  Cancer Discov       Date:  2018-06-07       Impact factor: 39.397

Review 3.  Ultrasonography of optic nerve sheath diameter for detection of raised intracranial pressure: a systematic review and meta-analysis.

Authors:  Julie Dubourg; Etienne Javouhey; Thomas Geeraerts; Mahmoud Messerer; Behrouz Kassai
Journal:  Intensive Care Med       Date:  2011-04-20       Impact factor: 17.440

4.  Amid FDA Approval Filings, Another CAR-T Therapy Patient Death.

Authors:  Jennifer Abbasi
Journal:  JAMA       Date:  2017-06-13       Impact factor: 56.272

5.  Inducible caspase-9 suicide gene controls adverse effects from alloreplete T cells after haploidentical stem cell transplantation.

Authors:  Xiaoou Zhou; Gianpietro Dotti; Robert A Krance; Caridad A Martinez; Swati Naik; Rammurti T Kamble; April G Durett; Olga Dakhova; Barbara Savoldo; Antonio Di Stasi; David M Spencer; Yu-Feng Lin; Hao Liu; Bambi J Grilley; Adrian P Gee; Cliona M Rooney; Helen E Heslop; Malcolm K Brenner
Journal:  Blood       Date:  2015-05-14       Impact factor: 22.113

6.  CD19 CAR-T cells of defined CD4+:CD8+ composition in adult B cell ALL patients.

Authors:  Cameron J Turtle; Laïla-Aïcha Hanafi; Carolina Berger; Theodore A Gooley; Sindhu Cherian; Michael Hudecek; Daniel Sommermeyer; Katherine Melville; Barbara Pender; Tanya M Budiarto; Emily Robinson; Natalia N Steevens; Colette Chaney; Lorinda Soma; Xueyan Chen; Cecilia Yeung; Brent Wood; Daniel Li; Jianhong Cao; Shelly Heimfeld; Michael C Jensen; Stanley R Riddell; David G Maloney
Journal:  J Clin Invest       Date:  2016-04-25       Impact factor: 14.808

7.  Endothelial Activation and Blood-Brain Barrier Disruption in Neurotoxicity after Adoptive Immunotherapy with CD19 CAR-T Cells.

Authors:  Juliane Gust; Kevin A Hay; Laïla-Aïcha Hanafi; Daniel Li; David Myerson; Luis F Gonzalez-Cuyar; Cecilia Yeung; W Conrad Liles; Mark Wurfel; Jose A Lopez; Junmei Chen; Dominic Chung; Susanna Harju-Baker; Tahsin Özpolat; Kathleen R Fink; Stanley R Riddell; David G Maloney; Cameron J Turtle
Journal:  Cancer Discov       Date:  2017-10-12       Impact factor: 39.397

Review 8.  Chimeric antigen receptor T-cell therapy - assessment and management of toxicities.

Authors:  Sattva S Neelapu; Sudhakar Tummala; Partow Kebriaei; William Wierda; Cristina Gutierrez; Frederick L Locke; Krishna V Komanduri; Yi Lin; Nitin Jain; Naval Daver; Jason Westin; Alison M Gulbis; Monica E Loghin; John F de Groot; Sherry Adkins; Suzanne E Davis; Katayoun Rezvani; Patrick Hwu; Elizabeth J Shpall
Journal:  Nat Rev Clin Oncol       Date:  2017-09-19       Impact factor: 66.675

9.  KTE-X19 CAR T-Cell Therapy in Relapsed or Refractory Mantle-Cell Lymphoma.

Authors:  Michael Wang; Javier Munoz; Andre Goy; Frederick L Locke; Caron A Jacobson; Brian T Hill; John M Timmerman; Houston Holmes; Samantha Jaglowski; Ian W Flinn; Peter A McSweeney; David B Miklos; John M Pagel; Marie-Jose Kersten; Noel Milpied; Henry Fung; Max S Topp; Roch Houot; Amer Beitinjaneh; Weimin Peng; Lianqing Zheng; John M Rossi; Rajul K Jain; Arati V Rao; Patrick M Reagan
Journal:  N Engl J Med       Date:  2020-04-02       Impact factor: 91.245

10.  Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia.

Authors:  Shannon L Maude; Theodore W Laetsch; Jochen Buechner; Susana Rives; Michael Boyer; Henrique Bittencourt; Peter Bader; Michael R Verneris; Heather E Stefanski; Gary D Myers; Muna Qayed; Barbara De Moerloose; Hidefumi Hiramatsu; Krysta Schlis; Kara L Davis; Paul L Martin; Eneida R Nemecek; Gregory A Yanik; Christina Peters; Andre Baruchel; Nicolas Boissel; Francoise Mechinaud; Adriana Balduzzi; Joerg Krueger; Carl H June; Bruce L Levine; Patricia Wood; Tetiana Taran; Mimi Leung; Karen T Mueller; Yiyun Zhang; Kapildeb Sen; David Lebwohl; Michael A Pulsipher; Stephan A Grupp
Journal:  N Engl J Med       Date:  2018-02-01       Impact factor: 91.245

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  7 in total

Review 1.  Application and Design of Switches Used in CAR.

Authors:  Paweł Głowacki; Piotr Rieske
Journal:  Cells       Date:  2022-06-13       Impact factor: 7.666

2.  Human Vaccines & Immunotherapeutics: news.

Authors: 
Journal:  Hum Vaccin Immunother       Date:  2021-05-04       Impact factor: 3.452

3.  Combinatorial antigen targeting strategies for acute leukemia: application in myeloid malignancy.

Authors:  Pinar Ataca Atilla; Mary K McKenna; Norihiro Watanabe; Maksim Mamonkin; Malcolm K Brenner; Erden Atilla
Journal:  Cytotherapy       Date:  2021-12-23       Impact factor: 5.414

Review 4.  Mechanisms of cytokine release syndrome and neurotoxicity of CAR T-cell therapy and associated prevention and management strategies.

Authors:  Xinyi Xiao; Shengkang Huang; Sifei Chen; Yazhuo Wang; Qihang Sun; Xinjie Xu; Yuhua Li
Journal:  J Exp Clin Cancer Res       Date:  2021-11-18

Review 5.  Cytokine Release Syndrome and Associated Acute Toxicities in Pediatric Patients Undergoing Immune Effector Cell Therapy or Hematopoietic Cell Transplantation.

Authors:  Susanne H C Baumeister; Gopi S Mohan; Alaa Elhaddad; Leslie Lehmann
Journal:  Front Oncol       Date:  2022-03-24       Impact factor: 6.244

6.  Combinatorial suicide gene strategies for the safety of cell therapies.

Authors:  Corey Falcon; Lauren Smith; Mustafa Al-Obaidi; Mohammed Abu Zaanona; Katelyn Purvis; Kentaro Minagawa; Mohammad Athar; Donna Salzman; Ravi Bhatia; Frederick Goldman; Antonio Di Stasi
Journal:  Front Immunol       Date:  2022-09-14       Impact factor: 8.786

Review 7.  CAR T cells: Building on the CD19 paradigm.

Authors:  Anat Globerson Levin; Isabelle Rivière; Zelig Eshhar; Michel Sadelain
Journal:  Eur J Immunol       Date:  2021-08-02       Impact factor: 6.688

  7 in total

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