Literature DB >> 3362162

Micronuclei in X-irradiated human lymphocytes.

C Kormos1, G J Köteles.   

Abstract

The dose-effect relationship of the frequency of micronuclei in cytokinesis-blocked human lymphocytes after in vitro irradiation of whole blood in the range from 0.2 to 4 Gy was studied. The linear-quadratic response obtained offers a useful technique for dose assessments in cases of radiation injuries above approx. 0.1 Gy whole body dose. The distribution in size of micronuclei in cytochalasin B treated cells ranges to larger diameters than in mononuclear lymphoblasts.

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Year:  1988        PMID： 3362162     DOI： 10.1016/0027-5107(88)90227-8

Source DB:  PubMed          Journal:  Mutat Res        ISSN： 0027-5107            Impact factor:   2.433


  8 in total

1.  The effect of electron and gamma irradiation on the induction of micronuclei in cytokinesis-blocked human blood lymphocytes.

Authors:  Santhosh Acharya; Ganesh Sanjeev; N N Bhat; K Siddappa; Y Narayana
Journal:  Radiat Environ Biophys       Date:  2009-01-14       Impact factor: 1.925

2.  Evidence for radiation hormesis after in vitro exposure of human lymphocytes to low doses of ionizing radiation.

Authors:  Kanokporn Noy Rithidech; Bobby R Scott
Journal:  Dose Response       Date:  2008-05-21       Impact factor: 2.658

3.  Dose rate effect on micronuclei induction in human blood lymphocytes exposed to single pulse and multiple pulses of electrons.

Authors:  Santhosh Acharya; N N Bhat; Praveen Joseph; Ganesh Sanjeev; B Sreedevi; Y Narayana
Journal:  Radiat Environ Biophys       Date:  2011-01-23       Impact factor: 1.925

4.  DNA damage in non-proliferating cells subjected to ionizing irradiation at high or low dose rates.

Authors:  R K Sachs; P Chen; P Hahnfeldt; D Lai; L R Hlatky
Journal:  J Math Biol       Date:  1993       Impact factor: 2.259

5.  Computerized image analysis for determining micronucleus frequency.

Authors:  S Szirmai; J Bérces; G J Köteles
Journal:  Environ Health Perspect       Date:  1993-10       Impact factor: 9.031

6.  Using the micronucleus assay to detect genotoxic effects of metal ions.

Authors:  J Bérces; M Otos; S Szirmai; C Crane-Uruena; G J Köteles
Journal:  Environ Health Perspect       Date:  1993-10       Impact factor: 9.031

Review 7.  The cytokinesis-block micronucleus technique and its application to genotoxicity studies in human populations.

Authors:  M Fenech
Journal:  Environ Health Perspect       Date:  1993-10       Impact factor: 9.031

8.  Genoprotective Effect of Some Flavonoids against Genotoxic Damage Induced by X-rays In Vivo: Relationship between Structure and Activity.

Authors:  Miguel Alcaraz; Amparo Olivares; Daniel Gyingiri Achel; José Antonio García-Gamuz; Julián Castillo; Miguel Alcaraz-Saura
Journal:  Antioxidants (Basel)       Date:  2021-12-30
  8 in total

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