Literature DB >> 33615192

Docking Prediction of Levodopa in the Receptor Binding Domain of Spike Protein of SARS-CoV-2.

Abdul Mannan Baig1, Areeba Khaleeq1, Hira Syeda2, Noor Bibi3.   

Abstract

Levodopa is a prodrug that is converted into dopamine, which replenishes the deficient dopamine in the brain of patients suffering from Parkinsonism. We hypothesize that levodopa may interact with the receptor binding domain of the SARS-CoV-2 and may act as a physical impediment to the viral entry into the host cell.
© 2021 American Chemical Society.

Entities:  

Year:  2021        PMID： 33615192      PMCID： PMC7887836          DOI： 10.1021/acsptsci.1c00002

Source DB:  PubMed          Journal:  ACS Pharmacol Transl Sci        ISSN： 2575-9108


  6 in total

1.  Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor.

Authors:  Jun Lan; Jiwan Ge; Jinfang Yu; Sisi Shan; Huan Zhou; Shilong Fan; Qi Zhang; Xuanling Shi; Qisheng Wang; Linqi Zhang; Xinquan Wang
Journal:  Nature       Date:  2020-03-30       Impact factor: 49.962

2.  GalaxyWEB server for protein structure prediction and refinement.

Authors:  Junsu Ko; Hahnbeom Park; Lim Heo; Chaok Seok
Journal:  Nucleic Acids Res       Date:  2012-05-30       Impact factor: 16.971

3.  DrugBank 4.0: shedding new light on drug metabolism.

Authors:  Vivian Law; Craig Knox; Yannick Djoumbou; Tim Jewison; An Chi Guo; Yifeng Liu; Adam Maciejewski; David Arndt; Michael Wilson; Vanessa Neveu; Alexandra Tang; Geraldine Gabriel; Carol Ly; Sakina Adamjee; Zerihun T Dame; Beomsoo Han; You Zhou; David S Wishart
Journal:  Nucleic Acids Res       Date:  2013-11-06       Impact factor: 16.971

4.  Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2.

Authors:  Yuanyuan Zhang; Yaning Li; Renhong Yan; Lu Xia; Yingying Guo; Qiang Zhou
Journal:  Science       Date:  2020-03-04       Impact factor: 47.728

5.  Elucidation of cellular targets and exploitation of the receptor-binding domain of SARS-CoV-2 for vaccine and monoclonal antibody synthesis.

Authors:  Abdul Mannan Baig; Areeba Khaleeq; Hira Syeda
Journal:  J Med Virol       Date:  2020-07-17       Impact factor: 20.693

6.  Structural basis of receptor recognition by SARS-CoV-2.

Authors:  Jian Shang; Gang Ye; Ke Shi; Yushun Wan; Chuming Luo; Hideki Aihara; Qibin Geng; Ashley Auerbach; Fang Li
Journal:  Nature       Date:  2020-03-30       Impact factor: 49.962
  6 in total
  2 in total

Review 1.  Methodology-Centered Review of Molecular Modeling, Simulation, and Prediction of SARS-CoV-2.

Authors:  Kaifu Gao; Rui Wang; Jiahui Chen; Limei Cheng; Jaclyn Frishcosy; Yuta Huzumi; Yuchi Qiu; Tom Schluckbier; Xiaoqi Wei; Guo-Wei Wei
Journal:  Chem Rev       Date:  2022-05-20       Impact factor: 72.087

2.  Dopamine Reduces SARS-CoV-2 Replication In Vitro through Downregulation of D2 Receptors and Upregulation of Type-I Interferons.

Authors:  Fiona Limanaqi; Silvia Zecchini; Borana Dino; Sergio Strizzi; Gioia Cappelletti; Olga Utyro; Claudia Vanetti; Micaela Garziano; Irma Saulle; Mario Clerici; Mara Biasin
Journal:  Cells       Date:  2022-05-19       Impact factor: 7.666
  2 in total

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