Literature DB >> 33614721

Squamous Cell Carcinoma Arising in Ungual Lichen Planus: Report and Review.

Caroline Maris Takatu1, Tatiana Villas Boas Gabbi1, Marcello Menta Simonsen Nico1.   

Abstract

BACKGROUND: Lichen planus (LP) can lead to severe scarring of the nail unit leading to anonychia. There are very few reports of squamous cell carcinoma (SCC) occurring in the lesions of ungual LP.
OBJECTIVE: The aim of this study was to revise the previously reported cases of SCC appearing in ungual LP and to present a new case.
METHODS: A PubMed search was performed with the terms "nail lichen planus" and "squamous cell carcinoma." Reported cases as well as a new case were depicted in a table.
RESULTS: Only 2 indexed articles reporting 3 cases were found. All patients suffered of long-lasting scarring ungual LP.
CONCLUSIONS: The occurrence of SCC in nail LP is rare. LP is not "premalignant" per se, but SCC might rarely arise in LP scars.
Copyright © 2020 by S. Karger AG, Basel.

Entities:  

Keywords:  Lichen planus; Marjolin ulcer; Nails; Squamous cell carcinoma; Verrucous carcinoma

Year:  2020        PMID: 33614721      PMCID: PMC7879240          DOI: 10.1159/000511094

Source DB:  PubMed          Journal:  Skin Appendage Disord        ISSN: 2296-9160


  9 in total

Review 1.  Cutaneous lichen planus and squamous cell carcinoma.

Authors:  G K Patel; R J Turner; R Marks
Journal:  J Eur Acad Dermatol Venereol       Date:  2003-01       Impact factor: 6.166

2.  Squamous cell carcinoma arising from lichen planus of nail matrix and nail bed.

Authors:  Naoko Okiyama; Takahiro Satoh; Hiroo Yokozeki; Kiyoshi Nishioka
Journal:  J Am Acad Dermatol       Date:  2005-11       Impact factor: 11.527

Review 3.  Ungual and periungual human papillomavirus-associated squamous cell carcinoma: a review.

Authors:  Catherine Riddel; Rashid Rashid; Val Thomas
Journal:  J Am Acad Dermatol       Date:  2011-02-18       Impact factor: 11.527

4.  Clinicopathological and prognostic characteristics of oral squamous cell carcinomas arising in patients with oral lichen planus: A systematic review and a comprehensive meta-analysis.

Authors:  Miguel Ángel González-Moles; Saman Warnakulasuriya; Isabel González-Ruiz; Lucía González-Ruiz; Ángela Ayén; Daniel Lenouvel; Isabel Ruiz-Ávila; Pablo Ramos-García
Journal:  Oral Oncol       Date:  2020-04-16       Impact factor: 5.337

Review 5.  [Verrucous squamous cell carcinoma complicating hypertrophic lichen planus. Three case reports and review of the literature].

Authors:  T K Friedl; M J Flaig; T Ruzicka; R A Rupec
Journal:  Hautarzt       Date:  2011-01       Impact factor: 0.751

6.  Squamous cell carcinoma in situ arising within lichen planus of the vulva.

Authors:  J M Franck; A W Young
Journal:  Dermatol Surg       Date:  1995-10       Impact factor: 3.398

Review 7.  The many faces of squamous cell carcinoma.

Authors:  S C Bernstein; K K Lim; D G Brodland; K A Heidelberg
Journal:  Dermatol Surg       Date:  1996-03       Impact factor: 3.398

Review 8.  Marjolin's ulcer in chronic wounds - review of available literature.

Authors:  Dariusz Bazaliński; Joanna Przybek-Mita; Beata Barańska; Paweł Więch
Journal:  Contemp Oncol (Pozn)       Date:  2017-09-29

9.  Squamous Cell Carcinomas in Two Cases of Nail Lichen Planus: Is There a Real Association?

Authors:  Claudia Costa; Alessia Villani; Daniela Russo; Milena Cappello; Gaia De Fata Salvatores; Massimiliano Scalvenzi
Journal:  Dermatol Ther (Heidelb)       Date:  2018-05-31
  9 in total
  1 in total

1.  Porokeratosis of the Nail Unit: Case Series and Review.

Authors:  Tatiana Mina Yendo; Tatiana Villas Boas Gabbi; Marcello Menta Simonsen Nico
Journal:  Skin Appendage Disord       Date:  2021-05-25
  1 in total

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