| Literature DB >> 33605059 |
Chunhua Xu1,2, Li Li1,2, Wei Wang1,2, Qian Zhang1,2, Xiuwei Zhang3, Rusong Yang4.
Abstract
The aim of this study was to investigate the value of serum macrophage inhibitory factor-1 (MIC-1) level in patients with non-small cell lung cancer (NSCLC). Serum samples from 296 patients with NSCLC and 240 healthy controls were collected. The levels of serum MIC-1 were determined by ELISA. The serum MIC-1 levels in NSCLC patients were higher than that of the controls (P <.001). Univariate and multivariate Cox regression analysis showed that serum MIC-1 was an independent prognostic indicator of OS and PFS. Serum MIC-1 is a valuable biomarker for the diagnosis and prognosis of NSCLC.Entities:
Keywords: diagnosis; macrophage inhibitory cytokine-1; non-small cell lung cancer; prognosis
Year: 2021 PMID: 33605059 PMCID: PMC7957168 DOI: 10.1111/jcmm.16360
Source DB: PubMed Journal: J Cell Mol Med ISSN: 1582-1838 Impact factor: 5.310