Literature DB >> 33601919

KPT-330 Prevents Aortic Valve Calcification via a Novel C/EBPβ Signaling Pathway.

Punashi Dutta1,2, Karthik M Kodigepalli1,2, Stephanie LaHaye3, J Will Thompson4, Sarah Rains4,5, Casey Nagel6, Kaitlyn Thatcher1,2, Robert B Hinton7, Joy Lincoln1,2.   

Abstract

[Figure: see text].

Entities:  

Keywords:  heart valves; mass spectrometry; signal transduction; transcription factors; valve disease

Mesh：

Substances：

Year:  2021        PMID： 33601919      PMCID： PMC8085092          DOI： 10.1161/CIRCRESAHA.120.318503

Source DB:  PubMed          Journal:  Circ Res        ISSN： 0009-7330            Impact factor:   17.367


  68 in total

1.  Differential activation of valvulogenic, chondrogenic, and osteogenic pathways in mouse models of myxomatous and calcific aortic valve disease.

Authors:  Jonathan D Cheek; Elaine E Wirrig; Christina M Alfieri; Jeanne F James; Katherine E Yutzey
Journal:  J Mol Cell Cardiol       Date:  2012-01-10       Impact factor: 5.000

2.  Nuclear export of phosphorylated C/EBPbeta mediates the inhibition of albumin expression by TNF-alpha.

Authors:  M Buck; L Zhang; N A Halasz; T Hunter; M Chojkier
Journal:  EMBO J       Date:  2001-12-03       Impact factor: 11.598

3.  A randomized trial of intensive lipid-lowering therapy in calcific aortic stenosis.

Authors:  S Joanna Cowell; David E Newby; Robin J Prescott; Peter Bloomfield; John Reid; David B Northridge; Nicholas A Boon
Journal:  N Engl J Med       Date:  2005-06-09       Impact factor: 91.245

4.  Association of cholesterol levels, hydroxymethylglutaryl coenzyme-A reductase inhibitor treatment, and progression of aortic stenosis in the community.

Authors:  Michael F Bellamy; Patricia A Pellikka; Kyle W Klarich; A Jamil Tajik; Maurice Enriquez-Sarano
Journal:  J Am Coll Cardiol       Date:  2002-11-20       Impact factor: 24.094

5.  In vivo genetic evidence for klotho-dependent, fibroblast growth factor 23 (Fgf23) -mediated regulation of systemic phosphate homeostasis.

Authors:  Teruyo Nakatani; Bara Sarraj; Mutsuko Ohnishi; Michael J Densmore; Takashi Taguchi; Regina Goetz; Moosa Mohammadi; Beate Lanske; M Shawkat Razzaque
Journal:  FASEB J       Date:  2008-10-03       Impact factor: 5.191

6.  Oxidation, inflammation, and aortic valve calcification peroxide paves an osteogenic path.

Authors:  Dwight A Towler
Journal:  J Am Coll Cardiol       Date:  2008-09-02       Impact factor: 24.094

7.  Cadherin-11 Overexpression Induces Extracellular Matrix Remodeling and Calcification in Mature Aortic Valves.

Authors:  Derek C Sung; Caitlin J Bowen; Kiran A Vaidya; Jingjing Zhou; Nikita Chapurin; Andrew Recknagel; Bin Zhou; Jonathan Chen; Michael Kotlikoff; Jonathan T Butcher
Journal:  Arterioscler Thromb Vasc Biol       Date:  2016-06-16       Impact factor: 8.311

8.  Calcification by valve interstitial cells is regulated by the stiffness of the extracellular matrix.

Authors:  Cindy Ying Yin Yip; Jan-Hung Chen; Ruogang Zhao; Craig A Simmons
Journal:  Arterioscler Thromb Vasc Biol       Date:  2009-03-19       Impact factor: 8.311

9.  Calcific Aortic Valve Disease: Molecular Mechanisms and Therapeutic Approaches.

Authors:  Daniel Alejandro Lerman; Sai Prasad; Nasri Alotti
Journal:  Eur Cardiol       Date:  2015

10.  Role of Noncanonical Wnt Signaling Pathway in Human Aortic Valve Calcification.

Authors:  Isabella Albanese; Bin Yu; Hamood Al-Kindi; Bianca Barratt; Leah Ott; Mohammad Al-Refai; Benoit de Varennes; Dominique Shum-Tim; Marta Cerruti; Ophélie Gourgas; Eric Rhéaume; Jean-Claude Tardif; Adel Schwertani
Journal:  Arterioscler Thromb Vasc Biol       Date:  2016-12-08       Impact factor: 8.311
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  4 in total

Review 1.  Innate and adaptive immunity: the understudied driving force of heart valve disease.

Authors:  Francesca Bartoli-Leonard; Jonas Zimmer; Elena Aikawa
Journal:  Cardiovasc Res       Date:  2021-11-22       Impact factor: 10.787

2.  Old Drugs for an Old Pathology? Drug Repurposing for Calcific Aortic Valve Disease.

Authors:  Francesca Bartoli-Leonard; Elena Aikawa
Journal:  Circ Res       Date:  2021-04-29       Impact factor: 17.367

Review 3.  Models and Techniques to Study Aortic Valve Calcification in Vitro, ex Vivo and in Vivo. An Overview.

Authors:  Maria Bogdanova; Arsenii Zabirnyk; Anna Malashicheva; Daria Semenova; John-Peder Escobar Kvitting; Mari-Liis Kaljusto; Maria Del Mar Perez; Anna Kostareva; Kåre-Olav Stensløkken; Gareth J Sullivan; Arkady Rutkovskiy; Jarle Vaage
Journal:  Front Pharmacol       Date:  2022-06-02       Impact factor: 5.988

4.  Increased TGFβ1 and SMAD3 Contribute to Age-Related Aortic Valve Calcification.

Authors:  Mrinmay Chakrabarti; Aniket Bhattacharya; Mengistu G Gebere; John Johnson; Zeeshan A Ayub; Ioulia Chatzistamou; Narendra R Vyavahare; Mohamad Azhar
Journal:  Front Cardiovasc Med       Date:  2022-07-19
  4 in total

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