Literature DB >> 33914606

Old Drugs for an Old Pathology? Drug Repurposing for Calcific Aortic Valve Disease.

Francesca Bartoli-Leonard1, Elena Aikawa2,3.   

Abstract

Entities:  

Keywords:  Editorials; XPO1; aortic valve disease; calcification; drug repositioning

Mesh：

Substances：

Year:  2021        PMID： 33914606      PMCID： PMC8095786          DOI： 10.1161/CIRCRESAHA.121.319149

Source DB:  PubMed          Journal:  Circ Res        ISSN： 0009-7330            Impact factor:   17.367


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  14 in total

Review 1.  Therapeutic targeting of nuclear protein import in pathological cell conditions.

Authors:  Mirna N Chahine; Grant N Pierce
Journal:  Pharmacol Rev       Date:  2009-09       Impact factor: 25.468

2.  Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease.

Authors:  Paul M Ridker; Brendan M Everett; Tom Thuren; Jean G MacFadyen; William H Chang; Christie Ballantyne; Francisco Fonseca; Jose Nicolau; Wolfgang Koenig; Stefan D Anker; John J P Kastelein; Jan H Cornel; Prem Pais; Daniel Pella; Jacques Genest; Renata Cifkova; Alberto Lorenzatti; Tamas Forster; Zhanna Kobalava; Luminita Vida-Simiti; Marcus Flather; Hiroaki Shimokawa; Hisao Ogawa; Mikael Dellborg; Paulo R F Rossi; Roland P T Troquay; Peter Libby; Robert J Glynn
Journal:  N Engl J Med       Date:  2017-08-27       Impact factor: 91.245

3.  Retinoids Repress Human Cardiovascular Cell Calcification With Evidence for Distinct Selective Retinoid Modulator Effects.

Authors:  Maximillian A Rogers; Jiaohua Chen; Shriram Nallamshetty; Tan Pham; Shinji Goto; Jochen D Muehlschlegel; Peter Libby; Masanori Aikawa; Elena Aikawa; Jorge Plutzky
Journal:  Arterioscler Thromb Vasc Biol       Date:  2019-12-19       Impact factor: 8.311

4.  Colchicine in Patients with Chronic Coronary Disease.

Authors:  Stefan M Nidorf; Aernoud T L Fiolet; Arend Mosterd; John W Eikelboom; Astrid Schut; Tjerk S J Opstal; Salem H K The; Xiao-Fang Xu; Mark A Ireland; Timo Lenderink; Donald Latchem; Pieter Hoogslag; Anastazia Jerzewski; Peter Nierop; Alan Whelan; Randall Hendriks; Henk Swart; Jeroen Schaap; Aaf F M Kuijper; Maarten W J van Hessen; Pradyot Saklani; Isabel Tan; Angus G Thompson; Allison Morton; Chris Judkins; Willem A Bax; Maurits Dirksen; Marco Alings; Graeme J Hankey; Charley A Budgeon; Jan G P Tijssen; Jan H Cornel; Peter L Thompson
Journal:  N Engl J Med       Date:  2020-08-31       Impact factor: 91.245

Review 5.  The nuclear export protein XPO1 - from biology to targeted therapy.

Authors:  Asfar S Azmi; Mohammed H Uddin; Ramzi M Mohammad
Journal:  Nat Rev Clin Oncol       Date:  2020-11-10       Impact factor: 66.675

6.  Spatiotemporal Multi-Omics Mapping Generates a Molecular Atlas of the Aortic Valve and Reveals Networks Driving Disease.

Authors:  Florian Schlotter; Arda Halu; Shinji Goto; Mark C Blaser; Simon C Body; Lang H Lee; Hideyuki Higashi; Daniel M DeLaughter; Joshua D Hutcheson; Payal Vyas; Tan Pham; Maximillian A Rogers; Amitabh Sharma; Christine E Seidman; Joseph Loscalzo; Jonathan G Seidman; Masanori Aikawa; Sasha A Singh; Elena Aikawa
Journal:  Circulation       Date:  2018-07-24       Impact factor: 29.690

7.  Valve Endothelial Cell-Derived Tgfβ1 Signaling Promotes Nuclear Localization of Sox9 in Interstitial Cells Associated With Attenuated Calcification.

Authors:  Danielle J Huk; Blair F Austin; Tori E Horne; Robert B Hinton; William C Ray; Donald D Heistad; Joy Lincoln
Journal:  Arterioscler Thromb Vasc Biol       Date:  2015-12-03       Impact factor: 8.311

8.  N-of-1 Trial of a Statin, Placebo, or No Treatment to Assess Side Effects.

Authors:  Frances A Wood; James P Howard; Judith A Finegold; Alexandra N Nowbar; David M Thompson; Ahran D Arnold; Christopher A Rajkumar; Susan Connolly; Jaimini Cegla; Chris Stride; Peter Sever; Christine Norton; Simon A M Thom; Matthew J Shun-Shin; Darrel P Francis
Journal:  N Engl J Med       Date:  2020-11-15       Impact factor: 91.245

9.  Surgical Explantation of Transcatheter Aortic Valve Bioprostheses: A Statewide Experience.

Authors:  Alexander A Brescia; G Michael Deeb; Stephane Leung Wai Sang; Daizo Tanaka; P Michael Grossman; Devraj Sukul; Chang He; Patricia F Theurer; Melissa Clark; Francis L Shannon; Stanley J Chetcuti; Shinichi Fukuhara
Journal:  Circ Cardiovasc Interv       Date:  2021-03-15       Impact factor: 6.546

10.  Estimated Research and Development Investment Needed to Bring a New Medicine to Market, 2009-2018.

Authors:  Olivier J Wouters; Martin McKee; Jeroen Luyten
Journal:  JAMA       Date:  2020-03-03       Impact factor: 157.335
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  2 in total

Review 1.  Innate and adaptive immunity: the understudied driving force of heart valve disease.

Authors:  Francesca Bartoli-Leonard; Jonas Zimmer; Elena Aikawa
Journal:  Cardiovasc Res       Date:  2021-11-22       Impact factor: 10.787

Review 2.  Uncoupling the Vicious Cycle of Mechanical Stress and Inflammation in Calcific Aortic Valve Disease.

Authors:  Nalin H Dayawansa; Sara Baratchi; Karlheinz Peter
Journal:  Front Cardiovasc Med       Date:  2022-03-09
  2 in total

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