Literature DB >> 33592293

Epidemiology of endovascular and open repair for abdominal aortic aneurysms in the United States from 2004 to 2015 and implications for screening.

Kirsten D Dansey1, Rens R B Varkevisser1, Nicholas J Swerdlow1, Chun Li1, Livia E V M de Guerre2, Patric Liang1, Christina Marcaccio1, Thomas F X O'Donnell1, Brett J Carroll3, Marc L Schermerhorn4.   

Abstract

BACKGROUND: Contemporary national trends in the repair of ruptured abdominal aortic aneurysms (AAAs) and intact AAAs are relatively unknown. Furthermore, screening is only covered by insurance for patients aged 65 to 75 years with a family history of AAAs and for men with a positive smoking history. It is unclear what proportion of patients who present with a ruptured AAA would have been candidates for screening.
METHODS: Using the National Inpatient Sample from 2004 to 2015, we identified ruptured and intact AAA admissions and repairs using the International Classification of Diseases codes. We generated the screening-eligible cohort using previously identified proportions of male smokers (87%) and all patients with a family history of AAAs (10%) and applied these proportions to patients aged 65 to 75 years. We accounted for those who could have had a previous AAA diagnosis (17%), either from screening or an incidental detection in patients aged >75 years who had presented with AAA rupture. The primary outcomes were treatment and in-hospital mortality between patients meeting the criteria for screening vs those who did not.
RESULTS: We evaluated 65,125 admissions for ruptured AAAs and 461,191 repairs for intact AAAs. Overall, an estimated 45,037 admitted patients (68%) and 25,777 patients who had undergone repair for ruptured AAAs (59%) did not meet the criteria for screening. Of the patients who did not qualify, 27,653 (63%) were aged >75 years, 10,603 (24%) were aged <65 years, and 16,103 (36%) were women. Endovascular AAA repair (EVAR) increased for ruptured AAAs from 10% in 2004 to 55% in 2015 (P < .001), with operative mortality of 35%. EVAR increased for intact AAAs from 45% in 2004 to 83% in 2015 (P < .001), with operative mortality of 2.0%.
CONCLUSIONS: Most patients who had undergone repair for ruptured AAAs did not qualify for screening. EVAR was the primary treatment of both ruptured and intact AAAs with relatively low in-hospital mortality. Therefore, expansion of the screening criteria to include selected women and a wider age range should be considered.
Copyright © 2021 Society for Vascular Surgery. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  AAA screening; Abdominal aortic aneurysm outcomes; Endovascular

Mesh:

Year:  2021        PMID: 33592293      PMCID: PMC8316377          DOI: 10.1016/j.jvs.2021.01.044

Source DB:  PubMed          Journal:  J Vasc Surg        ISSN: 0741-5214            Impact factor:   4.860


  39 in total

1.  Long-term benefit and cost-effectiveness analysis of screening for abdominal aortic aneurysms from a randomized controlled trial.

Authors:  J S Lindholt; J Sørensen; R Søgaard; E W Henneberg
Journal:  Br J Surg       Date:  2010-06       Impact factor: 6.939

2.  What a vascular surgeon should know about familial abdominal aortic aneurysm.

Authors:  K M van de Luijtgaarden; H J M Verhagen
Journal:  Eur J Vasc Endovasc Surg       Date:  2015-04-19       Impact factor: 7.069

3.  Outcomes of familial abdominal aortic aneurysm repair in the Vascular Quality Initiative.

Authors:  Evan J Ryer; Robert P Garvin; Yi Zhou; Haiyan Sun; Ahn Pham; Ksenia Orlova; James R Elmore
Journal:  J Vasc Surg       Date:  2018-07-29       Impact factor: 4.268

4.  National trends in open surgical, endovascular, and branched-fenestrated endovascular aortic aneurysm repair in Medicare patients.

Authors:  Bjoern D Suckow; Philip P Goodney; Jesse A Columbo; Ravinder Kang; David H Stone; Art Sedrakyan; Jack L Cronenwett; Mark F Fillinger
Journal:  J Vasc Surg       Date:  2017-12-28       Impact factor: 4.268

5.  Rupture of Abdominal Aortic Aneurysms in Patients Under Screening Age and Elective Repair Threshold.

Authors:  M T Laine; T Vänttinen; I Kantonen; K Halmesmäki; E M Weselius; S Laukontaus; J Salenius; P S Aho; M Venermo
Journal:  Eur J Vasc Endovasc Surg       Date:  2016-02-04       Impact factor: 7.069

Review 6.  Five Year Natural History of Screening Detected Sub-Aneurysms and Abdominal Aortic Aneurysms in 70 Year Old Women and Systematic Review of Repair Rate in Women.

Authors:  P Söderberg; A Wanhainen; S Svensjö
Journal:  Eur J Vasc Endovasc Surg       Date:  2017-04-04       Impact factor: 7.069

7.  Analysis of risk factors for abdominal aortic aneurysm in a cohort of more than 3 million individuals.

Authors:  K Craig Kent; Robert M Zwolak; Natalia N Egorova; Thomas S Riles; Andrew Manganaro; Alan J Moskowitz; Annetine C Gelijns; Giampaolo Greco
Journal:  J Vasc Surg       Date:  2010-07-13       Impact factor: 4.268

8.  Changes in abdominal aortic aneurysm rupture and short-term mortality, 1995-2008: a retrospective observational study.

Authors:  Marc L Schermerhorn; Rodney P Bensley; Kristina A Giles; Rob Hurks; A James Oʼmalley; Philip Cotterill; Elliot Chaikof; Bruce E Landon
Journal:  Ann Surg       Date:  2012-10       Impact factor: 12.969

9.  Modifiable risk factor burden and the prevalence of peripheral artery disease in different vascular territories.

Authors:  Jeffrey S Berger; Judith Hochman; Iryna Lobach; Mark A Adelman; Thomas S Riles; Caron B Rockman
Journal:  J Vasc Surg       Date:  2013-05-02       Impact factor: 4.268

10.  Primary Care Screening for Abdominal Aortic Aneurysm: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.

Authors:  Janelle M Guirguis-Blake; Tracy L Beil; Caitlyn A Senger; Erin L Coppola
Journal:  JAMA       Date:  2019-12-10       Impact factor: 56.272

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  3 in total

1.  Association between neighborhood deprivation and presenting with a ruptured abdominal aortic aneurysm before screening age.

Authors:  Amanda R Phillips; Elizabeth A Andraska; Katherine M Reitz; Salim Habib; Deirdre Martinez-Meehan; Yancheng Dai; Amber E Johnson; Nathan L Liang
Journal:  J Vasc Surg       Date:  2022-03-18       Impact factor: 4.860

2.  Exploring the Effect and Mechanism of Si-Miao-Yong-An Decoction on Abdominal Aortic Aneurysm Based on Mice Experiment and Bioinformatics Analysis.

Authors:  Zhenyu Xu; Lulu Zhang; Ning Huangfu; Fengchun Jiang; Kangting Ji; Shenghuang Wang
Journal:  Evid Based Complement Alternat Med       Date:  2022-05-31       Impact factor: 2.650

3.  Overview of screening eligibility in patients undergoing ruptured AAA repair from 2003 to 2019 in the Vascular Quality Initiative.

Authors:  Lucas Mota; Christina L Marcaccio; Kirsten D Dansey; Livia E V M de Guerre; Thomas F X O'Donnell; Peter A Soden; Sara L Zettervall; Marc L Schermerhorn
Journal:  J Vasc Surg       Date:  2021-10-22       Impact factor: 4.268

  3 in total

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