Literature DB >> 33585340

Missed Diagnosis of Cholangiocarcinoma Presenting with Atypical Symptoms.

Ren Kawamura1, Yukinori Harada1, Taro Shimizu1.   

Abstract

We report a case of delayed diagnosis of cholangiocarcinoma. A 62-year-old man developed acute abdominal pain in multiple sites. As the distribution pattern of the abdominal pain was not correctly interpreted based on the mechanisms of visceral and referred pain, the patient was not investigated with the best diagnostic test at first presentation. Moreover, miscommunication between physicians in a clinic and separate hospital delayed diagnosis. For prompt diagnosis, physicians should be practice careful reasoning and focus on good communication with physicians outside their hospital. LEARNING POINTS: Abdominal pain without jaundice can be an initial symptom in patients with cholangiocarcinoma.Cholangiocarcinoma in the lower common bile duct can present as lower abdominal pain referred through the 7th-11th thoracic nerves.Physicians can determine the origin of abdominal pain through correct interpretation of the distribution pattern of abdominal pain based on knowledge of pathophysiology. © EFIM 2021.

Entities:  

Keywords:  Cholangiocarcinoma; referred pain; visceral pain

Year:  2021        PMID: 33585340      PMCID: PMC7875580          DOI: 10.12890/2021_002207

Source DB:  PubMed          Journal:  Eur J Case Rep Intern Med        ISSN: 2284-2594


  5 in total

1.  Experimental pain in the stomach: a model based on electrical stimulation guided by gastroscopy.

Authors:  A M Drewes; L Arendt-Nielsen; J H Jensen; J B Hansen; H B Krarup; U Tage-Jensen
Journal:  Gut       Date:  1997-12       Impact factor: 23.059

Review 2.  Cholangiocarcinoma.

Authors:  Adeel S Khan; Leigh Anne Dageforde
Journal:  Surg Clin North Am       Date:  2019-02-10       Impact factor: 2.741

3.  The sites to which pain is referred from the common bile-duct in man and its implication for the theory of referred pain.

Authors:  F S Doran
Journal:  Br J Surg       Date:  1967-07       Impact factor: 6.939

Review 4.  Physiology of Visceral Pain.

Authors:  G F Gebhart; Klaus Bielefeldt
Journal:  Compr Physiol       Date:  2016-09-15       Impact factor: 9.090

Review 5.  Visceral pain: the ins and outs, the ups and downs.

Authors:  Shafaq Sikandar; Anthony H Dickenson
Journal:  Curr Opin Support Palliat Care       Date:  2012-03       Impact factor: 2.302

  5 in total

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