Literature DB >> 33584968

A Systematic Review Examining the Potential Adverse Effects of Microneedling.

Asha Gowda1,2,3, Brayden Healey1,2,3, Harib Ezaldein1,2,3, Miesha Merati1,2,3.   

Abstract

BACKGROUND: Microneedling is a relatively safe therapeutic procedure used to treat many dermatological conditions, including acne vulgaris, alopecia, melasma and other pigmentary disorders, as well as to promote skin rejuvenation, rhytide reduction, and scar remodeling. Given its popularity among patients and increasing use in the clinic and at home, we aim to explain the adverse effects associated with microneedling procedures.
OBJECTIVE: We reviewed the current literature describing microneedling and the complications that may accompany this therapeutic procedure. PubMed was searched to identify studies that involved microneedling procedures using the standard roller microneedling, stamp microneedling, pen-type microneedling, and/or fractional radiofrequency microneedling devices. The resulting publications included clinical trials, retrospective studies, and case reports, which were then thoroughly reviewed for description of potential or observed complications that arose secondary to the microneedling procedure.
RESULTS: In this systematic review, a total of 51 articles were reviewed, which included 1,029 patients who received microneedling procedures for a variety of different skin conditions. Overall, this review found that microneedling, regardless of the specific device used, is a relatively safe procedure with minimal adverse effects, including, but not limited to, expected erythema, pain, edema, and temporary skin irritation.
CONCLUSIONS: Microneedling has become an attractive treatment option for many patients with dermatological conditions. We advise that clinicians and patients be informed about the adverse side effects associated with microneedling so that the risk of preventable complications can be reduced or avoided.
Copyright © 2020. Matrix Medical Communications. All rights reserved.

Entities:  

Keywords:  Microneedling; adverse effects; systematic review

Year:  2021        PMID: 33584968      PMCID: PMC7869810     

Source DB:  PubMed          Journal:  J Clin Aesthet Dermatol        ISSN: 1941-2789


  51 in total

1.  Application of photodynamic therapy combined with pre-illumination microneedling in the treatment of actinic keratosis in organ transplant recipients.

Authors:  P L Bencini; M G Galimberti; G Pellacani; C Longo
Journal:  Br J Dermatol       Date:  2012-11       Impact factor: 9.302

2.  A pilot split-scalp study of combined fractional radiofrequency microneedling and 5% topical minoxidil in treating male pattern hair loss.

Authors:  A-J Yu; Y-J Luo; X-G Xu; L-L Bao; T Tian; Z-X Li; Y-X Dong; Y-H Li
Journal:  Clin Exp Dermatol       Date:  2018-06-27       Impact factor: 3.470

3.  Comparative study on efficacy and safety of 1550 nm Er:Glass fractional laser and fractional radiofrequency microneedle device for facial atrophic acne scar.

Authors:  Woong Suk Chae; Jun Young Seong; Ha Na Jung; Sook Hyun Kong; Min Ho Kim; Ho Seok Suh; Yu Sung Choi
Journal:  J Cosmet Dermatol       Date:  2015-03-23       Impact factor: 2.696

4.  Deep peeling using phenol versus percutaneous collagen induction combined with trichloroacetic acid 20% in atrophic post-acne scars; a randomized controlled trial.

Authors:  Tahra Mohamed Leheta; Rania Mounir Abdel Hay; Yehia Farouk El Garem
Journal:  J Dermatolog Treat       Date:  2012-05-08       Impact factor: 3.359

5.  Intralesional bleomycin injection vs microneedling-assisted topical bleomycin spraying in treatment of plantar warts.

Authors:  Mohamed R Al-Naggar; Ahmad S Al-Adl; Ali R Rabie; Mahmoud R Abdelkhalk; Mohamed L Elsaie
Journal:  J Cosmet Dermatol       Date:  2018-04-23       Impact factor: 2.696

6.  Facial allergic granulomatous reaction and systemic hypersensitivity associated with microneedle therapy for skin rejuvenation.

Authors:  Razieh Soltani-Arabshahi; Jillian W Wong; Keith L Duffy; Douglas L Powell
Journal:  JAMA Dermatol       Date:  2014-01       Impact factor: 10.282

7.  Efficacy of fractional microneedle radiofrequency device in the treatment of primary axillary hyperhidrosis: a pilot study.

Authors:  Miri Kim; Jae Yong Shin; Jungsoo Lee; Ji Young Kim; Sang Ho Oh
Journal:  Dermatology       Date:  2013-10-04       Impact factor: 5.366

8.  Efficacy of a needling device for the treatment of acne scars: a randomized clinical trial.

Authors:  Murad Alam; Sandra Han; Marisa Pongprutthipan; Wareeporn Disphanurat; Rohit Kakar; Michael Nodzenski; Natalie Pace; Natalie Kim; Simon Yoo; Emir Veledar; Emily Poon; Dennis P West
Journal:  JAMA Dermatol       Date:  2014-08       Impact factor: 10.282

9.  Comparison of Nonablative Fractional Erbium Laser 1,340 nm and Microneedling for the Treatment of Atrophic Acne Scars: A Randomized Clinical Trial.

Authors:  Thaís Cachafeiro; Gabriela Escobar; Gabriela Maldonado; Tania Cestari; Oly Corleta
Journal:  Dermatol Surg       Date:  2016-02       Impact factor: 3.398

10.  Efficacy of microneedling plus human stem cell conditioned medium for skin rejuvenation: a randomized, controlled, blinded split-face study.

Authors:  Hee Jung Lee; Eo Gin Lee; Sangjin Kang; Jong-Hyuk Sung; Hyung-Min Chung; Dong Hyun Kim
Journal:  Ann Dermatol       Date:  2014-09-26       Impact factor: 1.444

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  6 in total

1.  A Comparison of Microneedling versus Glycolic Acid Chemical Peel for the Treatment of Acne Scarring.

Authors:  Fatima Ishfaq; Rohan Shah; Shawana Sharif; Nadia Waqas; Marielle Jamgochian; Babar Rao
Journal:  J Clin Aesthet Dermatol       Date:  2022-06

Review 2.  Microneedling Monotherapy for Acne Scar: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Authors:  Yu-Chun Shen; Wen-Kuan Chiu; Yi-No Kang; Chiehfeng Chen
Journal:  Aesthetic Plast Surg       Date:  2022-04-14       Impact factor: 2.708

3.  Dermal Micro-coring for the Treatment of Moderate to Severe Facial Wrinkles.

Authors:  Lisa Gfrerer; Suzanne L Kilmer; Jill S Waibel; Roy G Geronemus; Brian S Biesman
Journal:  Plast Reconstr Surg Glob Open       Date:  2022-10-17

4.  A case of a delayed granulomatous reaction on the face following microneedling: A case report.

Authors:  Emma Heck; Danya Traboulsi
Journal:  SAGE Open Med Case Rep       Date:  2022-06-07

5.  A Successful Esthetic Approach of Gingival Depigmentation Using Microneedling Technique and Ascorbic Acid (Vitamin C).

Authors:  Diana Mostafa; Shaden M Alotaibi
Journal:  Case Rep Dent       Date:  2022-04-25

Review 6.  A Comprehensive Review of Non-Energy-Based Treatments for Atrophic Acne Scarring.

Authors:  Curtis Tam; Jeffrey Khong; Kevin Tam; Ruslan Vasilev; Wesley Wu; Salar Hazany
Journal:  Clin Cosmet Investig Dermatol       Date:  2022-03-14
  6 in total

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