Literature DB >> 26845539

Comparison of Nonablative Fractional Erbium Laser 1,340 nm and Microneedling for the Treatment of Atrophic Acne Scars: A Randomized Clinical Trial.

Thaís Cachafeiro1, Gabriela Escobar, Gabriela Maldonado, Tania Cestari, Oly Corleta.   

Abstract

BACKGROUND: The efficacy and safety of nonablative fractional laser for acne scars treatment has been described in several studies. Recently, microneedling treatment has been showing promising results with lower costs, quick healing time, and low risk of postinflammatory hyperpigmentation (PIH).
OBJECTIVE: To compare the effectiveness and safety of nonablative fractional erbium laser 1,340 nm and microneedling for the treatment of facial atrophic acne scars.
METHODS: Forty-six patients with atrophic facial acne scars were randomized to microneedling and laser groups, receiving 3 sessions performed monthly. Two blinded dermatologists applied the validated "Quantitative Global Grading System for Postacne Scarring" scale, before, 2 months, and 6 months after the treatment. Side effects were recorded at each follow-up visit and patient's satisfaction was evaluated.
RESULTS: Both groups showed a significant improvement, and there was no statistically significant difference between results of both therapies (p = .264). The erythema after each session was longer in the laser group and 13.6% subjects experienced PIH. No PIH was observed in the microneedling group.
CONCLUSION: This study shows that both nonablative fractional laser 1,340 nm and microneedling are comparable and effective in the treatment of atrophic acne scars. Microneedling is well tolerated, with fewer side effects and lower down time.

Entities:  

Mesh:

Year:  2016        PMID: 26845539     DOI: 10.1097/DSS.0000000000000597

Source DB:  PubMed          Journal:  Dermatol Surg        ISSN: 1076-0512            Impact factor:   3.398


  10 in total

Review 1.  A Systematic Review Examining the Potential Adverse Effects of Microneedling.

Authors:  Asha Gowda; Brayden Healey; Harib Ezaldein; Miesha Merati
Journal:  J Clin Aesthet Dermatol       Date:  2021-01-01

Review 2.  Nonablative Fractional Laser Resurfacing in Skin of Color: Evidence-based Review.

Authors:  Shivani B Kaushik; Andrew F Alexis
Journal:  J Clin Aesthet Dermatol       Date:  2017-06-01

Review 3.  Microneedling Monotherapy for Acne Scar: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Authors:  Yu-Chun Shen; Wen-Kuan Chiu; Yi-No Kang; Chiehfeng Chen
Journal:  Aesthetic Plast Surg       Date:  2022-04-14       Impact factor: 2.708

Review 4.  Acne Scarring-Pathogenesis, Evaluation, and Treatment Options.

Authors:  Deirdre Connolly; Ha Linh Vu; Kavita Mariwalla; Nazanin Saedi
Journal:  J Clin Aesthet Dermatol       Date:  2017-09-01

Review 5.  Microneedling: Advances and widening horizons.

Authors:  Aashim Singh; Savita Yadav
Journal:  Indian Dermatol Online J       Date:  2016 Jul-Aug

Review 6.  Review of applications of microneedling in dermatology.

Authors:  Christopher Iriarte; Olabola Awosika; Monica Rengifo-Pardo; Alison Ehrlich
Journal:  Clin Cosmet Investig Dermatol       Date:  2017-08-08

7.  Comprehensive molecular characterization of microneedling therapy in a human three-dimensional skin model.

Authors:  Laurenz Schmitt; Yvonne Marquardt; Philipp Amann; Ruth Heise; Laura Huth; Sylvia Wagner-Schiffler; Sebastian Huth; Jens-Malte Baron
Journal:  PLoS One       Date:  2018-09-20       Impact factor: 3.240

Review 8.  Recent advances of microneedles for biomedical applications: drug delivery and beyond.

Authors:  Jian Yang; Xinli Liu; Yunzhi Fu; Yujun Song
Journal:  Acta Pharm Sin B       Date:  2019-04-04       Impact factor: 11.413

Review 9.  A systematic review of treatments for acne scarring. Part 2: Energy-based techniques.

Authors:  Georgios Kravvas; Firas Al-Niaimi
Journal:  Scars Burn Heal       Date:  2018-08-16

Review 10.  Microneedling for the Treatment of Scars: An Update for Clinicians.

Authors:  Margit L W Juhasz; Joel L Cohen
Journal:  Clin Cosmet Investig Dermatol       Date:  2020-12-22
  10 in total

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