Literature DB >> 33581461

Using weak supervision and deep learning to classify clinical notes for identification of current suicidal ideation.

Marika Cusick1, Prakash Adekkanattu2, Thomas R Campion3, Evan T Sholle4, Annie Myers5, Samprit Banerjee6, George Alexopoulos7, Yanshan Wang8, Jyotishman Pathak9.   

Abstract

Mental health concerns, such as suicidal thoughts, are frequently documented by providers in clinical notes, as opposed to structured coded data. In this study, we evaluated weakly supervised methods for detecting "current" suicidal ideation from unstructured clinical notes in electronic health record (EHR) systems. Weakly supervised machine learning methods leverage imperfect labels for training, alleviating the burden of creating a large manually annotated dataset. After identifying a cohort of 600 patients at risk for suicidal ideation, we used a rule-based natural language processing approach (NLP) approach to label the training and validation notes (n = 17,978). Using this large corpus of clinical notes, we trained several statistical machine learning models-logistic classifier, support vector machines (SVM), Naive Bayes classifier-and one deep learning model, namely a text classification convolutional neural network (CNN), to be evaluated on a manually-reviewed test set (n = 837). The CNN model outperformed all other methods, achieving an overall accuracy of 94% and a F1-score of 0.82 on documents with "current" suicidal ideation. This algorithm correctly identified an additional 42 encounters and 9 patients indicative of suicidal ideation but missing a structured diagnosis code. When applied to a random subset of 5,000 clinical notes, the algorithm classified 0.46% (n = 23) for "current" suicidal ideation, of which 87% were truly indicative via manual review. Implementation of this approach for large-scale document screening may play an important role in point-of-care clinical information systems for targeted suicide prevention interventions and improve research on the pathways from ideation to attempt.
Copyright © 2021 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Deep learning; Machine learning; Natural language processing; Suicidal ideation; Weak supervision

Mesh:

Year:  2021        PMID: 33581461      PMCID: PMC8009838          DOI: 10.1016/j.jpsychires.2021.01.052

Source DB:  PubMed          Journal:  J Psychiatr Res        ISSN: 0022-3956            Impact factor:   4.791


  27 in total

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Authors:  W W Chapman; W Bridewell; P Hanbury; G F Cooper; B G Buchanan
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Authors:  Gregory E Simon; Eric Johnson; Jean M Lawrence; Rebecca C Rossom; Brian Ahmedani; Frances L Lynch; Arne Beck; Beth Waitzfelder; Rebecca Ziebell; Robert B Penfold; Susan M Shortreed
Journal:  Am J Psychiatry       Date:  2018-05-24       Impact factor: 18.112

3.  Incidence of suicide ideation and attempts in adults: the 13-year follow-up of a community sample in Baltimore, Maryland.

Authors:  W H Kuo; J J Gallo; A Y Tien
Journal:  Psychol Med       Date:  2001-10       Impact factor: 7.723

4.  The Columbia-Suicide Severity Rating Scale: initial validity and internal consistency findings from three multisite studies with adolescents and adults.

Authors:  Kelly Posner; Gregory K Brown; Barbara Stanley; David A Brent; Kseniya V Yershova; Maria A Oquendo; Glenn W Currier; Glenn A Melvin; Laurence Greenhill; Sa Shen; J John Mann
Journal:  Am J Psychiatry       Date:  2011-12       Impact factor: 18.112

5.  Risk factors for suicide in psychiatric outpatients: a 20-year prospective study.

Authors:  G K Brown; A T Beck; R A Steer; J R Grisham
Journal:  J Consult Clin Psychol       Date:  2000-06

6.  Prediction Models for Suicide Attempts and Deaths: A Systematic Review and Simulation.

Authors:  Bradley E Belsher; Derek J Smolenski; Larry D Pruitt; Nigel E Bush; Erin H Beech; Don E Workman; Rebecca L Morgan; Daniel P Evatt; Jennifer Tucker; Nancy A Skopp
Journal:  JAMA Psychiatry       Date:  2019-06-01       Impact factor: 21.596

Review 7.  What can natural language processing do for clinical decision support?

Authors:  Dina Demner-Fushman; Wendy W Chapman; Clement J McDonald
Journal:  J Biomed Inform       Date:  2009-08-13       Impact factor: 6.317

8.  Does response on the PHQ-9 Depression Questionnaire predict subsequent suicide attempt or suicide death?

Authors:  Gregory E Simon; Carolyn M Rutter; Do Peterson; Malia Oliver; Ursula Whiteside; Belinda Operskalski; Evette J Ludman
Journal:  Psychiatr Serv       Date:  2013-12-01       Impact factor: 3.084

9.  Does Suicidal Ideation as Measured by the PHQ-9 Predict Suicide Among VA Patients?

Authors:  Samantha A Louzon; Robert Bossarte; John F McCarthy; Ira R Katz
Journal:  Psychiatr Serv       Date:  2016-01-14       Impact factor: 3.084

Review 10.  Suicide prediction models: a critical review of recent research with recommendations for the way forward.

Authors:  Ronald C Kessler; Robert M Bossarte; Alex Luedtke; Alan M Zaslavsky; Jose R Zubizarreta
Journal:  Mol Psychiatry       Date:  2019-09-30       Impact factor: 15.992

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2.  Improving ascertainment of suicidal ideation and suicide attempt with natural language processing.

Authors:  Cosmin A Bejan; Michael Ripperger; Drew Wilimitis; Ryan Ahmed; JooEun Kang; Katelyn Robinson; Theodore J Morley; Douglas M Ruderfer; Colin G Walsh
Journal:  Sci Rep       Date:  2022-09-07       Impact factor: 4.996

  2 in total

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