| Literature DB >> 33580411 |
Zhiyi Zhang1, Jie Song1, Cao Xie1, Jun Pan1, Weiyue Lu1, Min Liu2.
Abstract
Pancreatic cancer is a highly malignant tumor and one of the primary causes of cancer-related death. Because pancreatic cancer is difficult to diagnose in the early course of the disease, most patients present with advanced lesions at the time of diagnosis, and only 20% of patients are eligible for surgery. Consequently, drug treatment has become extremely important. At present, the main treatment regimens for pancreatic cancer are gemcitabine and the FORFIRINOX and MPACT regimens. However, none of these regimens substantially improves the prognosis of patients with pancreatic cancer. Extensive efforts have been dedicated to the study of pancreatic cancer in recent years. With the development and clinical application of biological targeted drugs, the biological targeted treatment of tumors has been widely accepted. Therefore, this article used relevant clinical trial data to summarize the research progress of traditional chemotherapy drugs and biological targeted drugs for the treatment of pancreatic cancer.Entities:
Keywords: angiogenesis inhibitors; anti-metabolite drugs; biological targeted drugs; chemotherapy drugs; kinase inhibitors
Year: 2021 PMID: 33580411 DOI: 10.1208/s12248-021-00556-2
Source DB: PubMed Journal: AAPS J ISSN: 1550-7416 Impact factor: 4.009