Literature DB >> 33579691

Do not routinely offer imaging for uncomplicated low back pain.

Amanda M Hall1, Kris Aubrey-Bassler2, Bradley Thorne2, Chris G Maher3.   

Abstract

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Mesh:

Year:  2021        PMID: 33579691      PMCID: PMC8023332          DOI: 10.1136/bmj.n291

Source DB:  PubMed          Journal:  BMJ        ISSN: 0959-8138


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Less than 5-10% of all low back pain is due to a specific underlying spinal pathology The remaining 90-95% has no indication of a serious cause and should be managed with conservative treatments such as advice and reassurance, exercise, physical therapy, chiropractic care, cognitive-behavioural therapy, or pain management Diagnostic triage based on clinical history and examination can help distinguish between non-specific or more serious low back pain Imaging may do more harm than good when serious conditions are not suspected and is likely to prolong recovery in patients with non-specific low back pain Patients’ primary concerns of whether their pain is caused by something serious and what they should do to aid recovery can be addressed by sound education and reassurance, without the need for imaging

The clinical problem

The past two decades have seen a paradigm shift in the way we use imaging when managing low back pain (LBP). Imaging was once a routine part of the diagnostic workup for most cases of LBP. Evidence now indicates that imaging is useful only in the small subgroup of patients for whom there is suspicion of red flag conditions. These conditions include cancer, infection, inflammatory disease, fracture, and severe neurological deficits—which together account for only 5-10% of LBP presentations in primary care.1 For the remaining 90-95% of LBP cases (called non-specific or uncomplicated LBP), imaging will not guide management and can cause more harm than benefit. International guidelines2 and “Choosing Wisely” campaigns now encourage a diagnostic triage approach to identify those patients who require imaging (box 1). Given these advances in knowledge, imaging rates for LBP should be decreasing, but recent systematic reviews show the opposite, reporting that imaging has increased over the past 20 years3 and that at least a third of all images are unnessary.4 “Don’t routinely image patients with low back pain regardless of the duration of symptoms unless: (a) there are clinical reasons to suspect serious underlying pathology (i.e., red flags), or (b) imaging is necessary for the planning and/or execution of a particular evidenced-based therapeutic intervention on a specific spinal condition.”—Canadian Spine Society, Choosing Wisely Canada “Do not undertake imaging for low back pain in patients without indications of a serious underlying condition.”—Australian Rheumatology Association, Choosing Wisely Australia “Do not routinely offer imaging in a non-specialist setting for people with low back pain with or without sciatica. Consider imaging in specialist settings of care (for example, a musculoskeletal interface clinic or hospital) for people with low back pain with or without sciatica only if the result is likely to change management.”—Royal College of Physicians, Choosing Wisely UK

The evidence for change

Evidence from randomised controlled trials has established that imaging does not improve clinical outcomes, and several observational studies have linked liberal imaging with greater work absence and unnecessary use of health services.5 Unnecessary LBP imaging has the potential for harm. Perhaps the most obvious of these harms is exposure to radiation from x rays and computed tomography. Harm is also possible if a clinician acts on incidental findings from any imaging method, including magnetic resonance imaging (MRI), or if these findings are not appropriately explained to patients. For example, disc abnormalities such as bulging disc or degenerative disc disease are commonly seen on images but may not be the source of pain, as they are also seen on images in up to 97% of asymptomatic patients (table 1).6 Incidental findings may lead to further investigations, specialist referral, and more intensive treatment such as surgery, which limits access to those services for the patients who are in genuine need of such care.7 Incidental findings may also provoke worry or concern in patients from a labelling effect (possibly delaying recovery) if they fail to understand that these anomalies are common and benign.8 9
Table 1

Age-specific prevalence estimates of degenerative spine imaging findings in asymptomatic people6

Image findingPrevalence (%) of findings by age (years)
20304050607080
Disc degeneration37526880889396
Disc signal loss17335473869497
Disc height loss24344556677684
Disc bulge30405060697784
Disc protrusion29313336384043
Annular fissure19202223252729
Facet degeneration491832506983
Spondylolisthesis35814233550
Age-specific prevalence estimates of degenerative spine imaging findings in asymptomatic people6 Imaging and follow-up based on incidental findings affects the health system in terms of direct costs (such as cost of equipment, staff time to conduct the imaging, and time to interpret the image findings) and downstream costs (subsequent tests, referrals, and interventions, many of which are expensive and are of limited benefit for most patients with back pain). The downstream costs of imaging also affect patients and society due to indirect costs relating to out of pocket expenses for unnecessary interventions, as well as expenses related to lost work or household productivity.8 10 Two systematic reviews of six randomised controlled trials (1804 participants) both concluded that patients who received imaging without a clear clinical indication did not have improvements to pain, function, or quality of life compared with those who did not have imaging.11 12 Additionally, observational studies have found that those who received imaging when not indicated had greater use of health services such as injections and surgery and greater work absence than their counterparts who did not receive imaging.5 13 14 15 For example, a 2020 study of 405 965 US primary care patients found that those who had early MRI were more likely to undergo back surgery (1.48% v 0.12%) and take prescription opioids (35.1% v 28.6%), yet had higher pain score at 1-year follow-up (3.99 v 3.87) than those who did not get early MRI.16

Barriers to change

Lack of awareness of current back pain guidelines and knowledge about how to apply them in practice are likely contributors to the over-reliance on imaging in primary care. This is often exacerbated if institutional policies and practices around imaging are not aligned to the latest evidence. Recent systematic reviews suggest that the clinical environment itself may encourage physicians to over-order imaging due to (a) accommodating patient requests, (b) believing that imaging will reassure the patient, and (c) not having time to explain and justify a non-imaging approach.17 Reported less consistently in the literature, additional factors include worry about missing a specific pathology, not being aware of conservative interventions besides medication, and a lack of access to conservative management such as exercise therapy, physical therapy, chiropractic care, cognitive behavioural therapy, and pain management programmes.17 18

Patient perspectives

Clinicians often report that they order imaging when patients specifically request it. Systematic reviews of surveys and interviews suggest that about half of patients expect imaging from their health provider because they believe it can help rule out a sinister cause for the pain.19 Some patients also believe that imaging can identify the cause better than the clinician’s physical exam and facilitate a more tailored approach to treatment.19 There is still considerable uncertainty as to what alternatives to imaging would convey the diagnosis of non-specific LBP satisfactorily from the patient’s perspective. Future research should focus on this area to develop strategies for explaining LBP to patients.

How should practice change?

Practice changes in the following key areas are required to support appropriate imaging use: Diagnostic triage and management—Evidence suggests that, by conducting a more thorough diagnostic triage,20 clinicians can discern which patients fall into the category of non-specific LBP. Papers by Bardin et al20 and Traegar et al21 present a useful visual aid (fig 1) for conducting diagnostic triage in patients with LBP. Bardin et al’s visual aid also details evidence based treatments for patients assessed to have radicular syndrome or non-specific LBP. We have supplemented this with a decision support tool (fig 2) to help clinicians identify the small subgroup of patients with suspected red flag conditions who do need imaging. As detailed in figure 1, advise all patients with non-specific LBP or radicular syndromes, regardless of pain duration, to remain active and reassure them of a good prognosis.
Fig 1

Diagnostic triage for low back pain. (Adapted from Traegar et al21)

Fig 2

Decision aid based on the latest evidence for triaging LBP patients. (Imaging for all other conditions is probably not useful and may be harmful.) (Adapted from Bardin et al20)

Diagnostic triage for low back pain. (Adapted from Traegar et al21) Decision aid based on the latest evidence for triaging LBP patients. (Imaging for all other conditions is probably not useful and may be harmful.) (Adapted from Bardin et al20) Patient education—Offer patients with non-specific LBP reassurance that imaging is not required and provide advice on self management as first-line care. Box 2 summarises key points to cover when providing reassurance. Jenkins et al’s education booklet Understanding My Low Back Pain guides clinicians and patients through points to cover within a consultation22 and can be given to patients as an educational and treatment advice tool (see fig 3 for an example).
Fig 3

Screenshot from patient education booklet Understanding My Low Back Pain provided as a data supplement by Jenkins et al22 (available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154885/bin/12913_2018_3526_MOESM3_ESM.pdf)

Most cases of LBP are simple strains and sprains of the back that, while painful and unpleasant, improve rapidly just like a sprained ankle Having an image (x ray or CT or MRI scan) of your back does not usually help to find the cause of the back pain or guide treatment The treatment for most cases of back pain is the same whether imaging is used or not; and we have seen that those who have unnecessary imaging often have a delayed recovery Unnecessary imaging has some risks, including radiation exposure and delay in appropriate treatment, and has been associated with worse patient outcomes and an increase in unnecessary surgery You may know other people who have had an x ray, CT, or MRI of their back that showed “changes”; but most of the changes seen on imaging are normal and are more common the older you get, just like grey hair and wrinkles. As these changes also occur in people without back pain, their relevance is unclear Screenshot from patient education booklet Understanding My Low Back Pain provided as a data supplement by Jenkins et al22 (available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154885/bin/12913_2018_3526_MOESM3_ESM.pdf) Communication style—Findings from a recent qualitative study suggests four key behaviours from clinicians that can help patients feel reassured.23 Show that you “know the whole story” by summarising the patient’s medical history and conducting a thorough assessment Demonstrate empathy and communicate that you are qualified and experienced, helping the patient to feel that they are “seeing the right person” Reduce the use of generic statements such as “nothing to worry about” and recognise the patient’s distress Explain the likely cause(s) of LBP and provide a clear self management plan to help the patient understand and manage their LBP.22 Monitoring—Regularly monitor image ordering practices and LBP outcomes relative to peers. This will reassure clinicians that the changes to practice that they implement are effective and do not result in patient harm. We searched Medline and the Cochrane Library to identify published systematic reviews on (i) the use of LBP imaging, (ii) the concordance of imaging with guidelines, (iii) physician reported barriers to guideline adherence, (iv) patient expectations around LBP imaging, and (v) interventions that have been used to change LBP imaging practice. Additionally, we consulted experts in LBP and primary care on relevant published evidence and the most up to date LBP guidelines internationally. How will your referrals for imaging in people with low back pain change as a result of reading this article? Audit the number of spinal x rays and MRIs requested in your practice in the past six months. How many of those imaging requests are in line with the recommendations given in the diagnostic triage tool in fig 1? How might you go about providing reassurance that imaging is not required? Bradley Thorne is a patient advisor for the Primary Healthcare Research Unit Musculoskeletal Programme at Memorial University, Newfoundland. In this role, he has consulted on several projects related to improving the management of LBP. He has a special interest in back pain due to lived experiences with low back pain over many years. He reviewed a range of publicly available patient facing materials, as well as the published literature that informed the “Patient perspectives” section in addition to reviewing and commenting on subsequent versions of the manuscript.
  23 in total

1.  Imaging for low back pain: is clinical use consistent with guidelines? A systematic review and meta-analysis.

Authors:  Hazel J Jenkins; Aron S Downie; Chris G Maher; Niamh A Moloney; John S Magnussen; Mark J Hancock
Journal:  Spine J       Date:  2018-05-03       Impact factor: 4.166

2.  Diagnostic imaging for low back pain: advice for high-value health care from the American College of Physicians.

Authors:  Roger Chou; Amir Qaseem; Douglas K Owens; Paul Shekelle
Journal:  Ann Intern Med       Date:  2011-02-01       Impact factor: 25.391

3.  People with low back pain want clear, consistent and personalised information on prognosis, treatment options and self-management strategies: a systematic review.

Authors:  Yuan Z Lim; Louisa Chou; Rebecca Tm Au; Kl Maheeka D Seneviwickrama; Flavia M Cicuttini; Andrew M Briggs; Kaye Sullivan; Donna M Urquhart; Anita E Wluka
Journal:  J Physiother       Date:  2019-06-18       Impact factor: 7.000

4.  Avoiding the unintended consequences of growth in medical care: how might more be worse?

Authors:  E S Fisher; H G Welch
Journal:  JAMA       Date:  1999-02-03       Impact factor: 56.272

5.  Imaging versus no imaging for low back pain: a systematic review, measuring costs, healthcare utilization and absence from work.

Authors:  G P G Lemmers; W van Lankveld; G P Westert; P J van der Wees; J B Staal
Journal:  Eur Spine J       Date:  2019-02-22       Impact factor: 3.134

Review 6.  Diagnostic triage for low back pain: a practical approach for primary care.

Authors:  Lynn D Bardin; Peter King; Chris G Maher
Journal:  Med J Aust       Date:  2017-04-03       Impact factor: 7.738

Review 7.  Diagnosis and management of low-back pain in primary care.

Authors:  Adrian Traeger; Rachelle Buchbinder; Ian Harris; Chris Maher
Journal:  CMAJ       Date:  2017-11-13       Impact factor: 8.262

8.  Discharged and dismissed: A qualitative study with back pain patients discharged without treatment from orthopaedic consultations.

Authors:  Kathrin Braeuninger-Weimer; Naffis Anjarwalla; Tamar Pincus
Journal:  Eur J Pain       Date:  2019-05-28       Impact factor: 3.931

9.  Health care utilization and costs associated with adherence to clinical practice guidelines for early magnetic resonance imaging among workers with acute occupational low back pain.

Authors:  Janessa M Graves; Deborah Fulton-Kehoe; Jeffrey G Jarvik; Gary M Franklin
Journal:  Health Serv Res       Date:  2013-08-01       Impact factor: 3.402

10.  Observational Study of the Downstream Consequences of Inappropriate MRI of the Lumbar Spine.

Authors:  Josephine C Jacobs; Jeffrey G Jarvik; Roger Chou; Derek Boothroyd; Jeanie Lo; Andrea Nevedal; Paul G Barnett
Journal:  J Gen Intern Med       Date:  2020-09-28       Impact factor: 5.128

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3.  Development and measurement properties of the AxEL (attitude toward education and advice for low-back-pain) questionnaire.

Authors:  Edel T O'Hagan; Ian W Skinner; Matthew D Jones; Emma L Karran; Adrian C Traeger; Aidan G Cashin; Benedict M Wand; Siobhan M Schabrun; Sean O'Neill; Ian A Harris; James H McAuley
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4.  Appropriateness of referrals from primary care for lumbar MRI.

Authors:  Susanne Brogaard Krogh; Tue Secher Jensen; Nanna Rolving; Janus Nikolaj Laust Thomsen; Casper Brink Hansen; Christoffer Høj Werenberg; Erik Rasmussen; Rune Carlson; Rikke Krüger Jensen
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Review 5.  Broadening risk factor or disease definition as a driver for overdiagnosis: A narrative review.

Authors:  João Pedro Bandovas; Beatriz Leal; Catarina Reis-de-Carvalho; David Cordeiro Sousa; João Cruz Araújo; Pedro Peixoto; Susana Oliveira Henriques; António Vaz Carneiro
Journal:  J Intern Med       Date:  2022-04       Impact factor: 13.068

6.  Massage Therapy: A Person-Centred Approach to Chronic Pain.

Authors:  Richard Lebert; Monica Noy; Eric Purves; Jacqueline Tibbett
Journal:  Int J Ther Massage Bodywork       Date:  2022-09-01

7.  Unintended consequences: quantifying the benefits, iatrogenic harms and downstream cascade costs of musculoskeletal MRI in UK primary care.

Authors:  Imran Mohammed Sajid; Anand Parkunan; Kathleen Frost
Journal:  BMJ Open Qual       Date:  2021-07

8.  Development of a Patient-Oriented Intervention to Support Patient-Provider Conversations about Unnecessary Lower Back Pain Imaging.

Authors:  Maryam Madani Larijani; Cindy Dumba; Heather Thiessen; Angie Palen; Tracey Carr; Jason R Vanstone; Daryl R Fourney; Collin Hartness; Robert Parker; Gary Groot
Journal:  Int J Environ Res Public Health       Date:  2021-03-09       Impact factor: 3.390

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