Literature DB >> 33573654

A retrospective analysis and literature review of neoplastic appendiceal mucinous lesions.

Belén Matias-García1, Fernando Mendoza-Moreno1, Ana Blasco-Martínez2, José Ignacio Busteros-Moraza2, Manuel Diez-Alonso1, Francisca Garcia-Moreno Nisa3.   

Abstract

BACKGROUND: At present, the term mucocele is outdated, and mucinous appendiceal neoplasm is preferred. Mucinous appendiceal neoplasm is an uncommon pathology that occurs predominantly in middle-aged women. Its classification and management have been the subject of debate in recent decades. The aim of this study was to analyse the incidence, clinical management and survival of these tumours diagnosed in our centre in the last 10 years.
METHODS: This was a retrospective observational study of patients with a diagnosis of appendiceal neoplasms between 2009 and 2018 in our centre. Variables such as sex, age, tumour type, clinical status, diagnosis, treatment and survival were collected. All data were analysed using the statistical program IBM SPSS Statistic® version 25.
RESULTS: Twenty-nine patients with a diagnosis of appendiceal neoplasm were identified, and 24 corresponded to neoplastic appendiceal mucinous lesions (85.7%). The average age was 59.7 ± 17.6 years. Most patients were women (15 cases; 62.5%). Most of them presented with chronic abdominal pain (37.5%), and the diagnosis was performed by computed tomography (CT) (50%). The treatment was surgical in all cases. The surgical technique depended on the findings and histology of the tumour.
CONCLUSION: Mucinous appendiceal neoplasms are an uncommon entity, and their pathological classification and management have recently changed.

Entities:  

Keywords:  Appendix; Low-grade appendiceal mucinous neoplasm; Mucinous neoplasm; Mucocele

Mesh:

Year:  2021        PMID: 33573654      PMCID: PMC7877070          DOI: 10.1186/s12893-021-01091-9

Source DB:  PubMed          Journal:  BMC Surg        ISSN: 1471-2482            Impact factor:   2.102


  19 in total

1.  [Mucocele of the appendix: Presentation of 31 cases].

Authors:  Arturo García Lozano; Antonio Vázquez Tarrago; Carmen Castro García; José Richart Aznar; Segundo Gómez Abril; Manuel Martínez Abad
Journal:  Cir Esp       Date:  2009-12-05       Impact factor: 1.653

2.  Appendiceal mucinous cystadenoma.

Authors:  A Rouchaud; L Glas; M Gayet; M F Bellin
Journal:  Diagn Interv Imaging       Date:  2014-01       Impact factor: 4.026

Review 3.  Evaluation of appendiceal mucinous neoplasms with a new classification system and literature review.

Authors:  Özgecan Gündoğar; Elife Kımıloğlu; Neslihan Komut; Merve Cin; Sibel Bektaş; Doğan Gönüllü; Ahmet Serkan İlgün; Nusret Erdoğan
Journal:  Turk J Gastroenterol       Date:  2018-09       Impact factor: 1.852

4.  Comment on management and prognosis of low-grade appendiceal mucinous neoplasms: A clinicopathologic analysis of 50 cases.

Authors:  Sami Akbulut; Tevfik Tolga Sahin
Journal:  Eur J Surg Oncol       Date:  2020-07-31       Impact factor: 4.424

5.  Unusual histopathological findings in appendectomy specimens: a retrospective analysis and literature review.

Authors:  Sami Akbulut; Mahmut Tas; Nilgun Sogutcu; Zulfu Arikanoglu; Murat Basbug; Abdullah Ulku; Heybet Semur; Yusuf Yagmur
Journal:  World J Gastroenterol       Date:  2011-04-21       Impact factor: 5.742

6.  Low-grade Appendiceal Mucinous Neoplasm of Uncertain Malignant Potential (LAMN-UMP): Prognostic Factors and Implications for Treatment and Follow-up.

Authors:  Keith Fournier; Safia Rafeeq; Melissa Taggart; Paul Kanaby; Jing Ning; Hsiang-Chun Chen; Michael Overman; Kanwal Raghav; Cathy Eng; Paul Mansfield; Richard Royal
Journal:  Ann Surg Oncol       Date:  2016-09-22       Impact factor: 5.344

7.  Nomenclature of appendiceal mucinous lesions according to the 2019 WHO Classification of Tumors of the Digestive System.

Authors:  Cemalettin Koç; Sami Akbulut; Ayşe Nur Akatlı; Emine Türkmen Şamdancı; Adem Tuncer; Sezai Yılmaz
Journal:  Turk J Gastroenterol       Date:  2020-09       Impact factor: 1.852

8.  Significance of proximal margin involvement in low-grade appendiceal mucinous neoplasms.

Authors:  Thomas Arnason; Michal Kamionek; Michelle Yang; Rhonda K Yantiss; Joseph Misdraji
Journal:  Arch Pathol Lab Med       Date:  2014-06-27       Impact factor: 5.534

9.  Diagnosis and Treatment of Mucinous Appendiceal Neoplasm Presented as Acute Appendicitis.

Authors:  Ioannis Kehagias; Apollon Zygomalas; Georgios Markopoulos; Thanasis Papandreou; Pantelis Kraniotis
Journal:  Case Rep Oncol Med       Date:  2016-03-14

10.  A prospective study of discrepancy between clinical and pathological diagnosis of appendiceal mucinous neoplasm.

Authors:  Han Deok Kwak; Jae Kyun Ju
Journal:  Ann Surg Treat Res       Date:  2020-02-28       Impact factor: 1.859

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  2 in total

1.  Appendiceal mucocele presenting as a leading point in ileocolic intussusceptions: "Case report".

Authors:  Gosa Bejiga
Journal:  Int J Surg Case Rep       Date:  2022-06-14

2.  A rare case of a large low-grade appendicular mucinous neoplasm causing compressive symptoms.

Authors:  John R Ekblad; Sidra B Bhuller; John Weaver; Michael E Bertocchi
Journal:  J Surg Case Rep       Date:  2022-04-13
  2 in total

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