Literature DB >> 33572980

Cross-Sectional Study of Plant Sterols Intake as a Basis for Designing Appropriate Plant Sterol-Enriched Food in Indonesia.

Drajat Martianto1,2, Atikah Bararah3, Nuri Andarwulan1,3, Dominika Średnicka-Tober4.   

Abstract

Coronary heart disease (CHD) is one of the leading causes of mortality in many low-income and middle-income countries, including Indonesia, with elevated blood cholesterol level being one of significant risk factors for this condition. The problem should be addressed by combining healthy lifestyle and diet, where functional foods having a cholesterol-lowering activity could play a significant role. A group of compounds that had been proven to show cholesterol-lowering ability are plant sterols. To develop more suitable functional foods that could substantially contribute to hypercholesterolemia prevention in Indonesian population, up-to-date data about plant sterols dietary intake are required, and were not available until this research was done. This study aimed to estimate daily plant sterols intake and to determine the consumption pattern of foods containing plant sterols in rural and urban area of Bogor, West Java, Indonesia. The research was conducted with a cross-sectional design, with 200 respondents. The study revealed that the level of plant sterols intake in Bogor reached on average 229.76 mg/day and was not significantly different between urban and rural area. Cereals, vegetables, and fruit products were the main food sources of plant sterols in both areas. In addition, a list of several surveyed food items possible to be enriched with plant sterols was developed within the study. These results provide baseline data to develop functional foods fortified with plant sterols suitable for the Indonesian needs and taste. However, further studies are needed to confirm efficacy and safety of introducing such phytosterol-enriched products into a habitual diet, especially considering possible long-term side effects of plant sterol treatment.

Entities:  

Keywords:  cardiovascular risk; cholesterol; fortification; functional food; phytosterols

Mesh:

Substances:

Year:  2021        PMID: 33572980      PMCID: PMC7912629          DOI: 10.3390/nu13020452

Source DB:  PubMed          Journal:  Nutrients        ISSN: 2072-6643            Impact factor:   5.717


  52 in total

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Authors:  Peter Clifton
Journal:  Atheroscler Suppl       Date:  2002-10       Impact factor: 3.235

2.  Estimation of plant sterol and cholesterol intake in Finland: quality of new values and their effect on intake.

Authors:  L M Valsta; A Lemström; M-L Ovaskainen; A-M Lampi; J Toivo; T Korhonen; V Piironen
Journal:  Br J Nutr       Date:  2004-10       Impact factor: 3.718

3.  Phytosterol feeding causes toxicity in ABCG5/G8 knockout mice.

Authors:  Allison L McDaniel; Heather M Alger; Janet K Sawyer; Kathryn L Kelley; Nancy D Kock; J Mark Brown; Ryan E Temel; Lawrence L Rudel
Journal:  Am J Pathol       Date:  2013-02-01       Impact factor: 4.307

4.  Potential risks associated with increased plasma plant-sterol levels.

Authors:  B Vergès; F Fumeron
Journal:  Diabetes Metab       Date:  2014-12-09       Impact factor: 6.041

5.  Relationships of serum plant sterols (phytosterols) and cholesterol in 595 hypercholesterolemic subjects, and familial aggregation of phytosterols, cholesterol, and premature coronary heart disease in hyperphytosterolemic probands and their first-degree relatives.

Authors:  C J Glueck; J Speirs; T Tracy; P Streicher; E Illig; J Vandegrift
Journal:  Metabolism       Date:  1991-08       Impact factor: 8.694

6.  Dietary xenosterols lead to infertility and loss of abdominal adipose tissue in sterolin-deficient mice.

Authors:  Curzio Solca; G Stephen Tint; Shailendra B Patel
Journal:  J Lipid Res       Date:  2012-11-23       Impact factor: 5.922

7.  Association of natural intake of dietary plant sterols with carotid intima-media thickness and blood lipids in Chinese adults: a cross-section study.

Authors:  Ping Wang; Yu-ming Chen; Li-ping He; Chao-gang Chen; Bo Zhang; Wen-qiong Xue; Yi-xiang Su
Journal:  PLoS One       Date:  2012-03-07       Impact factor: 3.240

Review 8.  Plant sterols and cardiovascular disease: a systematic review and meta-analysis.

Authors:  Bernd Genser; Günther Silbernagel; Guy De Backer; Eric Bruckert; Rafael Carmena; M John Chapman; John Deanfield; Olivier S Descamps; Ernst R Rietzschel; Karen C Dias; Winfried März
Journal:  Eur Heart J       Date:  2012-02       Impact factor: 29.983

Review 9.  Stroke Epidemiology in South, East, and South-East Asia: A Review.

Authors:  Narayanaswamy Venketasubramanian; Byung Woo Yoon; Jeyaraj Pandian; Jose C Navarro
Journal:  J Stroke       Date:  2017-09-29       Impact factor: 6.967

10.  The Burden of Cardiovascular Disease Attributable to Major Modifiable Risk Factors in Indonesia.

Authors:  Mohammad Akhtar Hussain; Abdullah Al Mamun; Sanne Ae Peters; Mark Woodward; Rachel R Huxley
Journal:  J Epidemiol       Date:  2016-03-26       Impact factor: 3.211

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  3 in total

1.  Antioxidants Such as Flavonoids and Carotenoids in the Diet of Bogor, Indonesia Residents.

Authors:  Nuri Andarwulan; Niken Cahyarani Puspita; Dominika Średnicka-Tober
Journal:  Antioxidants (Basel)       Date:  2021-04-11

Review 2.  The Bioavailability and Biological Activities of Phytosterols as Modulators of Cholesterol Metabolism.

Authors:  Xiang Li; Yan Xin; Yuqian Mo; Pavel Marozik; Taiping He; Honghui Guo
Journal:  Molecules       Date:  2022-01-14       Impact factor: 4.411

Review 3.  An Overview on the Therapeutic Function of Foods Enriched with Plant Sterols in Diabetes Management.

Authors:  Selvaraj Jayaraman; Anitha Roy; Srinivasan Vengadassalapathy; Ramya Sekar; Vishnu Priya Veeraraghavan; Ponnulakshmi Rajagopal; Gayathri Rengasamy; Raktim Mukherjee; Durairaj Sekar; Reji Manjunathan
Journal:  Antioxidants (Basel)       Date:  2021-11-27
  3 in total

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