Wenjie Zhou1, Feng Wang2, Marko Magic1,3, Minjie Zhuang1, Jian Sun4, Yiqun Wu5. 1. Department of Second Dental Center, Ninth People's Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai Key Laboratory of Stomatology, National Clinical Research Center of Stomatology, 280 Mohe Road, Shanghai, 201999, China. 2. Department of Oral Implantology, Ninth People's Hospital Affiliated with Shanghai Jiao Tong University, School of Medicine, Shanghai Key Laboratory of Stomatology, National Clinical Research Center of Stomatology, 639 Zhizaoju Road, Shanghai, 200011, China. 3. School of Dental Medicine, University of Belgrade, Belgrade, Serbia. 4. Department of Oral Maxillofacial-Head Neck Oncology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, National Clinical Research Center of Stomatology, 639 Zhizaoju Road, Shanghai, 200011, China. 5. Department of Second Dental Center, Ninth People's Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai Key Laboratory of Stomatology, National Clinical Research Center of Stomatology, 280 Mohe Road, Shanghai, 201999, China. yiqunwu@hotmail.com.
Abstract
OBJECTIVES: To assess how anatomy and osteogenesis correlated with results of maxillary sinus floor augmentation (MSFA). MATERIALS AND METHODS: Patients with partial edentulism and advanced atrophy of the posterior maxillae (≤ 4 mm residual bone height, RBH) underwent MSFA with sole deproteinized bovine bone matrix (DBBM) through a lateral approach. After a 6 to 9-month healing period, bone core biopsies were obtained from the sites of implant insertion for histological evaluation. The correlations between anatomical and histomorphometric variables were analyzed in a multiple regression model. RESULTS: Forty-nine patients were recruited. One biopsy per patient was obtained from the augmented sinus. Thirty-seven bone core biopsies were intact and met the requirement for histomorphometry analysis. The mean (± standard deviation) percentages of vital bone (VB), remaining DBBM, and non-mineralized tissue were 18.25 ± 4.76%, 27.74 ± 6.68%, and 54.08 ± 6.07%, respectively. No statistically significant correlations were found between RBH and VB% (p = 0.44) or between sinus contour and VB% (p = 0.33). However, there was an inverse correlation between the sinus width (SW) and VB % (SW1: R2 = 0.13, p = 0.03; SW2: R2 = 0.15, p = 0.02). CONCLUSIONS: After a healing period of 6-9 months, wider sinuses augmented with DBBM alone tended to have a lower proportion of new bone formation, while RBH and sinus contour did not appear to affect osteogenesis after MSFA. CLINICAL RELEVANCE: This study emphasized the effect of anatomy on osteogenesis after MSFA. The result of the study may have an indication to the clinician that SW is a consideration when selecting the bone grafting material and deciding the healing period of MSFA.
OBJECTIVES: To assess how anatomy and osteogenesis correlated with results of maxillary sinus floor augmentation (MSFA). MATERIALS AND METHODS:Patients with partial edentulism and advanced atrophy of the posterior maxillae (≤ 4 mm residual bone height, RBH) underwent MSFA with sole deproteinized bovine bone matrix (DBBM) through a lateral approach. After a 6 to 9-month healing period, bone core biopsies were obtained from the sites of implant insertion for histological evaluation. The correlations between anatomical and histomorphometric variables were analyzed in a multiple regression model. RESULTS: Forty-nine patients were recruited. One biopsy per patient was obtained from the augmented sinus. Thirty-seven bone core biopsies were intact and met the requirement for histomorphometry analysis. The mean (± standard deviation) percentages of vital bone (VB), remaining DBBM, and non-mineralized tissue were 18.25 ± 4.76%, 27.74 ± 6.68%, and 54.08 ± 6.07%, respectively. No statistically significant correlations were found between RBH and VB% (p = 0.44) or between sinus contour and VB% (p = 0.33). However, there was an inverse correlation between the sinus width (SW) and VB % (SW1: R2 = 0.13, p = 0.03; SW2: R2 = 0.15, p = 0.02). CONCLUSIONS: After a healing period of 6-9 months, wider sinuses augmented with DBBM alone tended to have a lower proportion of new bone formation, while RBH and sinus contour did not appear to affect osteogenesis after MSFA. CLINICAL RELEVANCE: This study emphasized the effect of anatomy on osteogenesis after MSFA. The result of the study may have an indication to the clinician that SW is a consideration when selecting the bone grafting material and deciding the healing period of MSFA.
Authors: Alessandro Scala; Daniele Botticelli; Idelmo Garcia Rangel; José Américo de Oliveira; Roberta Okamoto; Niklaus Peter Lang Journal: Clin Oral Implants Res Date: 2010-12 Impact factor: 5.977
Authors: Dieter Busenlechner; Christian D Huber; Christoph Vasak; Antonia Dobsak; Reinhard Gruber; Georg Watzek Journal: Clin Oral Implants Res Date: 2009-06-10 Impact factor: 5.977
Authors: Michael Schweikert; Daniele Botticelli; José Américo de Oliveira; Alessandro Scala; Luiz A Salata; Niklaus P Lang Journal: Clin Oral Implants Res Date: 2011-04-25 Impact factor: 5.977