Literature DB >> 33567574

Protocol for Prevention and Monitoring of Surgical Site Infections in Implant-Based Breast Reconstruction: Preliminary Results.

Giovanni Papa1, Andrea Frasca1, Nadia Renzi1, Chiara Stocco1, Giuseppe Pizzolato1, Vittorio Ramella1, Zoran Marij Arnež1.   

Abstract

Surgical site infection in implant-based breast reconstruction is a complication with variable incidence reported in the literature. Due to potential loss of implant and reconstruction, it can have a strong psychological impact on patients. Background and objectives: This study aimed primarily at analyzing the current status of the surgical site infection (SSI), (type, time of onset, clinical presentation, pathogens and management) in patients who underwent implant-based breast reconstruction at our Breast Unit. Secondarily, we wanted to establish whether introduction of a new, updated evidence-based protocol for infection prevention can reduce SSI in implant-based breast reconstruction. Materials and
Methods: A single-center retrospective study was performed primarily to evaluate the incidence and features of SSI after implant-based breast reconstruction from 2007 to 2020. In June 2020, a protocol for prevention of SSI in implant-based breast reconstruction was introduced in clinical practice. Secondarily, a data analysis of all patients who underwent implant-based breast reconstruction in compliance with this protocol was performed after preliminarily assessing its efficacy.
Results: 756 women were evaluated after mastectomy and implant-based breast reconstruction for breast cancer. A total of 26 surgical site infections were detected. The annual incidence of SSI decreased over time (range 0-11.76%). Data relating to infections' features, involved pathogens and implemented treatments were obtained. Since the introduction of the protocol, 22 patients have been evaluated, for a total of 29 implants. No early infections occurred. Conclusions: Surgical site infection rates at our Breast Unit are comparable to those reported in the literature. The SSI rates have shown a decreasing trend over the years. No SSI has occurred since the introduction of the prevention protocol for surgical site infection in June 2020.

Entities:  

Keywords:  antibiotic prophylaxis; breast reconstruction; complication; implant; infection; prevention

Mesh:

Year:  2021        PMID: 33567574      PMCID: PMC7915384          DOI: 10.3390/medicina57020151

Source DB:  PubMed          Journal:  Medicina (Kaunas)        ISSN: 1010-660X            Impact factor:   2.430


  37 in total

1.  Are Prophylactic Postoperative Antibiotics Necessary for Immediate Breast Reconstruction? Results of a Prospective Randomized Clinical Trial.

Authors:  Brett T Phillips; Mitchell S Fourman; Muath Bishawi; Mary Zegers; Brian J O'Hea; Jason C Ganz; Tara L Huston; Alexander B Dagum; Sami U Khan; Duc T Bui
Journal:  J Am Coll Surg       Date:  2016-03-04       Impact factor: 6.113

2.  Antibiotic Prophylaxis and Resistance in Surgical Site Infection After Immediate Tissue Expander Reconstruction of the Breast.

Authors:  Meghan C McCullough; Carrie K Chu; Claire S Duggal; Albert Losken; Grant W Carlson
Journal:  Ann Plast Surg       Date:  2016-11       Impact factor: 1.539

3.  Breast reconstruction following nipple-sparing mastectomy: predictors of complications, reconstruction outcomes, and 5-year trends.

Authors:  Amy S Colwell; Oren Tessler; Alex M Lin; Eric Liao; Jonathan Winograd; Curtis L Cetrulo; Rong Tang; Barbara L Smith; William G Austen
Journal:  Plast Reconstr Surg       Date:  2014-03       Impact factor: 4.730

4.  Comparison of 2-Year Complication Rates Among Common Techniques for Postmastectomy Breast Reconstruction.

Authors:  Katelyn G Bennett; Ji Qi; Hyungjin M Kim; Jennifer B Hamill; Andrea L Pusic; Edwin G Wilkins
Journal:  JAMA Surg       Date:  2018-10-01       Impact factor: 14.766

5.  Acellular human dermis implantation in 153 immediate two-stage tissue expander breast reconstructions: determining the incidence and significant predictors of complications.

Authors:  Anuja K Antony; Colleen M McCarthy; Peter G Cordeiro; Babak J Mehrara; Andrea L Pusic; Esther H Teo; Alexander F Arriaga; Joseph J Disa
Journal:  Plast Reconstr Surg       Date:  2010-06       Impact factor: 4.730

6.  Late Surgical-Site Infection in Immediate Implant-Based Breast Reconstruction.

Authors:  Indranil Sinha; Andrea L Pusic; Edwin G Wilkins; Jennifer B Hamill; Xiaoxue Chen; Hyungjin M Kim; Gretchen Guldbrandsen; Yoon S Chun
Journal:  Plast Reconstr Surg       Date:  2017-01       Impact factor: 4.730

7.  Infection following implant-based reconstruction in 1952 consecutive breast reconstructions: salvage rates and predictors of success.

Authors:  Richard G Reish; Branimir Damjanovic; William G Austen; Jonathan Winograd; Eric C Liao; Curtis L Cetrulo; Daniel M Balkin; Amy S Colwell
Journal:  Plast Reconstr Surg       Date:  2013-06       Impact factor: 4.730

8.  A systematic review of infection rates and associated antibiotic duration in acellular dermal matrix breast reconstruction.

Authors:  Brett T Phillips; Muath Bishawi; Alexander B Dagum; Duc T Bui; Sami U Khan
Journal:  Eplasty       Date:  2014-11-11

9.  Breast cancer in women: a descriptive analysis of the national cancer database.

Authors:  Andrea Sisti; Maria T Huayllani; Daniel Boczar; David J Restrepo; Aaron C Spaulding; Gabriel Emmanuel; Sanjay P Bagaria; Sarah A McLaughlin; Alexander S Parker; Antonio J Forte
Journal:  Acta Biomed       Date:  2020-05-11

Review 10.  Infection prevention in breast implant surgery - A review of the surgical evidence, guidelines and a checklist.

Authors:  S P Barr; A R Topps; N L P Barnes; J Henderson; S Hignett; R L Teasdale; A McKenna; J R Harvey; C C Kirwan
Journal:  Eur J Surg Oncol       Date:  2016-02-27       Impact factor: 4.424

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  1 in total

1.  Is Iatrogenic Implant Contamination Preventable Using a 16-Step No-Touch Protocol?

Authors:  Dylan Singh; Ruixue Zhang; Kaitlin H Hori; Fereydoun D Parsa
Journal:  Eplasty       Date:  2022-08-24
  1 in total

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