| Literature DB >> 3356479 |
V Pancré1, J Y Cesbron, C Auriault, M Joseph, J Chandenier, A Capron.
Abstract
Platelets isolated from patients infected with filariasis were cytotoxic for microfilariae in vitro. Moreover, platelets from normal donors acquired killing properties in the presence of serum from infected individuals. The humoral factor involved in this cytotoxic process was shown to be IgE. This IgE-dependent cytotoxicity of platelets was strongly inhibited by antigen-stimulated T lymphocyte supernatants from filarial patients.Entities:
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Year: 1988 PMID： 3356479 DOI： 10.1159/000234556
Source DB: PubMed Journal: Int Arch Allergy Appl Immunol ISSN： 0020-5915