Literature DB >> 12412752

Antibodies in human filariasis sera react with diethylcarbamazine.

B Ravindran, A K Satapathy, T Hussain, A M Pattnaik.   

Abstract

We demonstrate by an ELISA the presence of antibodies in human filarial sera that react with diethylcarbamazine (DEC); they appear to be primarily filarial antibodies cross-reacting with DEC skeleton, since affinity-purified DEC antibodies strongly react with Wuchereria bancrofti microfilariae. These observations indicate a possible antigenic mimicry between the drug and some parasite component.

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Year:  1989        PMID： 12412752      PMCID： PMC1534679     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  5 in total

1.  IgE antibodies against piperazine and N-methyl-piperazine in two asthmatic subjects.

Authors:  H Welinder; L Hagmar; C Gustavsson
Journal:  Int Arch Allergy Appl Immunol       Date:  1986

2.  IgE-dependent killing of Brugia malayi microfilariae by human platelets and its modulation by T cell products.

Authors:  V Pancré; J Y Cesbron; C Auriault; M Joseph; J Chandenier; A Capron
Journal:  Int Arch Allergy Appl Immunol       Date:  1988

3.  Platelets mediate the action of diethylcarbamazine on microfilariae.

Authors:  J Y Cesbron; A Capron; B B Vargaftig; M Lagarde; J Pincemail; P Braquet; H Taelman; M Joseph
Journal:  Nature       Date:  1987 Feb 5-11       Impact factor: 49.962

4.  Antibodies to diethylcarbamazine cross-react with microfilariae of Wuchereria bancrofti.

Authors:  B Ravindran; A K Satapathy; N M Pattnaik
Journal:  Immunol Lett       Date:  1988-01       Impact factor: 3.685

5.  Diethylcarbamazine enhances antibody-mediated cellular adherence to Brugia malayi microfilariae.

Authors:  W F Piessens; M Beldekas
Journal:  Nature       Date:  1979 Dec 20-27       Impact factor: 49.962
  5 in total

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