Literature DB >> 33564313

Heterotopic Pancreas in the Gallbladder: Case Report and Literature Review.

Emad Aborajooh1, Ibrahim Khalil Khairi Ghayada2, Yasser Mustafa Issa Lafi2.   

Abstract

INTRODUCTION: Heterotopic pancreas (HP) is the congenital presence of pancreatic tissue outside its normal location in the absence of vascular and anatomical connection with the main pancreas. HP can affect any part of the gastrointestinal tract, and it is mostly encountered in the stomach. The gallbladder is a rare site of HP, and our literature review revealed that only 38 cases were reported. We present a case of HP in the gallbladder that was presented with a picture of acute cholecystitis. After the case presentation, we will discuss HP in the gallbladder by reviewing the literature. Case Presentation. A 49-year-old male presented to the emergency department complaining of progressively worsening right upper abdominal pain for the last 24 hours. After thorough history and physical examination, a provisional diagnosis of acute cholecystitis was made. Abdominal ultrasonography revealed a rim of edema surrounding the gallbladder wall with two stones impacted at the gallbladder neck. Laparoscopic cholecystectomy was performed with an uneventful postoperative course, and the patient was discharged the next day. Microscopic examination of the gallbladder showed that a heterotopic pancreatic tissue, composed of a large number of pancreatic acini and few ducts with the absence of islets of Langerhans, was found around the cystic duct. The patient was asymptomatic at the regular follow-up six months postoperatively.
CONCLUSION: HP in the gallbladder is an extremely rare finding. Its clinical presentation is not different from other cholecystopathic diseases. Most cases were accompanied by cholelithiasis. Preoperative laboratory and imaging modalities are usually not helpful in the diagnosis of HP in the gallbladder. The definitive diagnosis is made by histological examination of the gallbladder specimen. Laparoscopic cholecystectomy is sufficing treatment.
Copyright © 2021 Emad Aborajooh et al.

Entities:  

Year:  2021        PMID: 33564313      PMCID: PMC7867455          DOI: 10.1155/2021/6611291

Source DB:  PubMed          Journal:  Case Rep Med


  37 in total

Review 1.  Heterotopic pancreas--an unusual cause of cholecystitis.

Authors:  B D Bhana; R Chetty
Journal:  S Afr J Surg       Date:  1999-11       Impact factor: 0.375

2.  Acute hemorrhage from aberrant pancreatic tissue in the gallbladder.

Authors:  I J VIDGOFF; A LEWIS
Journal:  Calif Med       Date:  1961-05

3.  Heterotopic pancreas of the gallbladder associated with chronic cholecystitis and high levels of amylasuria.

Authors:  Thanasis Klimis; Nikolaos Roukounakis; Ilias Kafetzis; Vasileios Mouziouras; Ilias Karantonis; Nikolaos Andromanakos
Journal:  JOP       Date:  2011-09-09

Review 4.  Heterotopic pancreatic tissue in the gallbladder. Two case reports and brief review of the literature.

Authors:  G Cerullo; D Marrelli; G Di Mare; M Onorati; S Tripodi; A Neri; F Roviello
Journal:  G Chir       Date:  2011-05

5.  [Heterotopic pancreatic tissue in the wall of the gallbladder].

Authors:  D Hadzi-Nikolov; M Resl; B Herzig; M Svĕtlík
Journal:  Cesk Patol       Date:  1997-11

6.  Aberrant pancreatic tissue accompanied by heterotopic gastric mucosa in the gall-bladder.

Authors:  M Murakami; Y Tsutsumi
Journal:  Pathol Int       Date:  1999-06       Impact factor: 2.534

7.  Heterotopic pancreatic tissue obstructing the gallbladder neck: a case report.

Authors:  Justin L Weppner; Matthew R Wilson; Robert Ricca; Paul A Lucha
Journal:  JOP       Date:  2009-09-04

8.  Ectopic pancreas in gallbladder. Clinical significance, diagnostic and therapeutic implications.

Authors:  Elena Margarita Sanchiz Cárdenas; Rocío Soler Humanes; Ana I Lavado Fernández; Rafael Díaz Nieto; Miguel A Suárez Muñoz
Journal:  Rev Esp Enferm Dig       Date:  2015-11       Impact factor: 2.086

9.  [Pancreatic choristoma in the gallbladder: report of two cases].

Authors:  Marcelo A Beltrán; Carlos Barría; Cecilia Naquira; Jorge Almonacid; Karina S Cruces
Journal:  Rev Med Chil       Date:  2007-12-20       Impact factor: 0.553

10.  Ectopic Pancreatic Tissue Adherent to the External Gallbladder Wall.

Authors:  Ioannis M Koukourakis; Meltem S Perente Memet; Maria Kouroupi; Konstantinos Simopoulos
Journal:  Case Rep Gastroenterol       Date:  2018-04-24
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  2 in total

1.  The rare entity of ectopic pancreatic tissue in the gallbladder: A case report.

Authors:  Georgios Chatziantoniou; Georgios Tzikos; Aristeidis Ioannidis; Antonia Loukousia; Georgia Raptou; Antonios Michalopoulos; Daniel Paramythiotis
Journal:  Ann Med Surg (Lond)       Date:  2022-04-29

2.  A case report of ectopic pancreatic tissue in the gallbladder.

Authors:  Anzel Jansen van Rensburg; Kasra Raufian
Journal:  J Surg Case Rep       Date:  2022-03-22
  2 in total

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