| Literature DB >> 3356357 |
H Humphreys1, S Bourke, C Dooley, D McKenna, B Power, C T Keane, E C Sweeney, C O'Moráin.
Abstract
This study investigated the effect of colloidal bismuth subcitrate and cimetidine on Campylobacter pylori in peptic disease. In 74% of 135 patients with peptic disease diagnosed at endoscopy C pylori was detected before treatment. Compared with cimetidine, colloidal bismuth subcitrate significantly decreased the incidence of C pylori after six weeks of treatment (p less than 0.001). In the colloidal bismuth subcitrate group, subsequent healing of the lesion was correlated with the clearance of C pylori, unlike in the cimetidine group. C pylori was strongly associated with the presence of histological gastritis, which was decreased by colloidal bismuth subcitrate (p less than 0.001).Entities:
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Year: 1988 PMID: 3356357 PMCID: PMC1433591 DOI: 10.1136/gut.29.3.279
Source DB: PubMed Journal: Gut ISSN: 0017-5749 Impact factor: 23.059