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Literature DB >> 3356052

MAC of sevoflurane in humans and the New Zealand white rabbit.

M S Scheller¹, L J Saidman, B L Partridge.

Abstract

The minimum alveolar concentration of sevoflurane necessary to prevent movement in 50 per cent of patients (MAC) was determined to be 2.05 per cent in 20 adult surgical patients. Because this value was higher than the only other experimentally determined human MAC value for sevoflurane (1.71 per cent), MAC was also determined in New Zealand white rabbits. Comparisons of the MAC ratios of sevoflurane to other volatile anaesthetics in both the human and the rabbit suggest that the human MAC value we obtained for sevoflurane is consistent with experimental determinations of MAC of other volatile anaesthetics in humans.

Entities: Chemical Species

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Year: 1988 PMID： 3356052 DOI： 10.1007/BF03010656

Source DB: PubMed Journal: Can J Anaesth ISSN： 0832-610X Impact factor: 5.063

8 in total

1. Minimum alveolar concentrations (MAC) of isoflurande with and without nitrous oxide in patients of various ages.

Authors: W C Stevens; W M Dolan; R T Gibbons; A White; E I Eger; R D Miller; R H DeJong; R M Elashoff
Journal: Anesthesiology Date: 1975-02 Impact factor: 7.892

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Authors: D R Waud
Journal: J Pharmacol Exp Ther Date: 1972-12 Impact factor: 4.030

3. The minimum alveolar concentration of enflurane in man.

Authors: H Gion; L J Saidman
Journal: Anesthesiology Date: 1971-10 Impact factor: 7.892

4. The relationship between age and halothane requirement in man.

Authors: G A Gregory; E I Eger; E S Munson
Journal: Anesthesiology Date: 1969-05 Impact factor: 7.892

5. Minimum alveolar concentrations of methoxyflurane, halothane, ether and cyclopropane in man: correlation with theories of anesthesia.

Authors: L J Saidman; E I Eger; E S Munson; A A Babad; M Muallem
Journal: Anesthesiology Date: 1967 Nov-Dec Impact factor: 7.892

6. Manipulation of rat brain fatty acid composition alters volatile anesthetic potency.

Authors: A S Evers; W J Elliott; J B Lefkowith; P Needleman
Journal: J Clin Invest Date: 1986-03 Impact factor: 14.808

7. The minimum alveolar concentration (MAC) of sevoflurane in humans.

Authors: T Katoh; K Ikeda
Journal: Anesthesiology Date: 1987-03 Impact factor: 7.892

8. MAC for halothane, enflurane, and isoflurane in the New Zealand white rabbit: and a test for the validity of MAC determinations.

Authors: J C Drummond
Journal: Anesthesiology Date: 1985-03 Impact factor: 7.892

8 in total

47 in total

Review 1. General anaesthetic actions on ligand-gated ion channels.

Authors: M D Krasowski; N L Harrison
Journal: Cell Mol Life Sci Date: 1999-08-15 Impact factor: 9.261

2. Factors affecting the rate of disappearance of sevoflurane in Baralyme.

Authors: D T Wong; J Lerman
Journal: Can J Anaesth Date: 1992-04 Impact factor: 5.063

Review 3. [Pharmacokinetic-pharmacodynamic models for inhaled anaesthetics].

Authors: S Kreuer; J Bruhn; W Wilhelm; T Bouillon
Journal: Anaesthesist Date: 2007-06 Impact factor: 1.041

4. Comparison of sevoflurane and other volatile anesthetics for cesarean section.

Authors: K Kan; A Shigihara; C Tase; A Okuaki
Journal: J Anesth Date: 1995-12 Impact factor: 2.078

5. Circulatory and catecholamine responses to tracheal intubation and skin incision during sevoflurane, isoflurane, or halothane anesthesia.

Authors: K Yamada; K Shingu; H Kimura; S Ikeda; K Tsushima; T Imanishi; K Murao
Journal: J Anesth Date: 1997-06 Impact factor: 2.078