| Literature DB >> 33560155 |
Jenny A Higgins1, Renee D Kramer2, Kelsey Q Wright3, Bethany Everett4,5, David K Turok5, Jessica N Sanders5.
Abstract
Few large, longitudinal studies document multiple contraceptive methods' effects on sexual functioning, satisfaction, and well-being. We leveraged data from the HER Salt Lake Contraceptive Initiative, a prospective cohort study with patient surveys at baseline, one month, and three months. Surveys assessed bleeding changes, contraceptive-related side effects, sexual functioning and satisfaction, and perceptions of methods' impact on sexual well-being. Individuals in the final sample (N = 2,157) initiated either combined oral contraceptives, levonorgestrel intrauterine devices (IUDs), copper IUDs, implants, injectables, or vaginal rings. Across methods, participants exhibited minimal changes in sexual function (Female Sexual Function Index-6 scores) or satisfaction (New Scale of Sexual Satisfaction scores) over three months. However, many perceived contraception-related changes to sexual well-being. Half (51%) reported their new method had made their sex life better; 15% reported it had made their sex life worse. Sexual improvements were associated with decreased vaginal bleeding, fewer side effects, and IUD use. Negative sexual impacts were associated with physical side effects (e.g., bloating and breast tenderness), increased bleeding, and vaginal ring use. In conclusion, contraceptive users did not experience major changes in sexual functioning or satisfaction over three months, but they did report subjective sexual changes, mostly positive, due to their method.Entities:
Mesh:
Substances:
Year: 2021 PMID: 33560155 PMCID: PMC8349922 DOI: 10.1080/00224499.2021.1873225
Source DB: PubMed Journal: J Sex Res ISSN: 0022-4499
Figure 1.Flowchart of inclusion criteria for analytic sample.
Demographic characteristics, sample of family-planning clients initiating a new contraceptive method (N = 2,157).
| Overall ( | Implant ( | Copper IUD ( | LNg IUD ( | Injectable ( | Oral Contraceptives ( | Vaginal Ring ( | ||
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| % | % | % | % | % | % | % | ||
| Age | ||||||||
| 18–19 | 20.1 | 22.1 | 12.5 | 19.3 | 25.2 | 24.1 | 12.6 | |
| 20–24 | 41.5 | 49.7 | 37.3 | 38.3 | 36.7 | 44.3 | 34.5 | |
| 25–29 | 22.8 | 19.5 | 28.0 | 24.7 | 19.5 | 19.7 | 31.0 | |
| 30–34 | 9.6 | 5.6 | 13.8 | 10.5 | 12.8 | 7.8 | 11.5 | |
| 35+ | 5.9 | 3.2 | 8.4 | 7.3 | 5.8 | 4.2 | 10.3 | |
| Highest level of education completed | ||||||||
| Did not complete high school | 4.8 | 6.4 | 2.9 | 4.5 | 4.0 | 4.7 | 6.9 | |
| High school or GED | 37.8 | 40.2 | 30.9 | 32.7 | 52.2 | 42.1 | 33.3 | |
| Some associate, vocational, technical training, or college | 41.0 | 41.6 | 42.1 | 42.8 | 33.2 | 39.6 | 47.1 | |
| Completed four-year college or higher | 16.4 | 11.9 | 24.1 | 20.0 | 10.6 | 13.6 | 12.6 | |
| Race and ethnicity | ||||||||
| Non-Hispanic White | 65.5 | 60.2 | 68.8 | 70.6 | 57.5 | 64.0 | 72.4 | |
| Hispanic non-White | 22.8 | 28.6 | 19.3 | 18.5 | 28.3 | 22.2 | 21.8 | |
| Non-White, non-Hispanic other[ | 11.7 | 11.1 | 11.9 | 10.9 | 14.2 | 13.9 | 5.8 | |
| Poverty category | ||||||||
| At or below poverty level | 41.0 | 43.3 | 37.0 | 36.6 | 55.8 | 41.3 | 35.6 | |
| 101%–199% above poverty level | 29.0 | 27.6 | 27.7 | 29.6 | 23.5 | 34.4 | 29.9 | |
| 200%–299% above poverty level | 19.1 | 19.1 | 21.2 | 20.6 | 15.0 | 17.5 | 17.2 | |
| 300% or more above poverty level | 10.9 | 9.9 | 14.2 | 13.2 | 5.8 | 6.9 | 17.2 | |
| Relationship status | ||||||||
| Married | 12.3 | 12.7 | 12.5 | 13.2 | 11.1 | 11.1 | 10.3 | |
| Cohabiting or committed relationship | 50.5 | 51.7 | 51.8 | 50.4 | 50.0 | 49.3 | 46.0 | |
| Actively dating | 19.6 | 17.7 | 19.9 | 18.7 | 19.5 | 22.4 | 25.3 | |
| Single | 11.3 | 11.9 | 9.3 | 12.0 | 13.3 | 9.7 | 11.5 | |
| Other[ | 6.3 | 6.0 | 6.4 | 5.8 | 6.2 | 7.5 | 6.9 | |
| Sexual orientation | ||||||||
| Heterosexual or mostly heterosexual | 87.4 | 88.1 | 87.8 | 86.6 | 86.3 | 87.5 | 92.0 | |
| Other[ | 12.6 | 11.9 | 12.2 | 13.4 | 13.7 | 12.5 | 8.1 | |
Note. Data presented are for complete cases on baseline variables, and percentages indicate the column proportion for the specific variable. Descriptive data are presented on the nonimputed original data set. Some columns may add to slightly less than or greater than 100%; these summations are due to rounding errors; LNg = levonorgestrel; IUD = intrauterine device.
P values reflect Kruskal–Wallis tests conditional on ties for ordinal variables (age, education, poverty) and χ2 tests for categorical variables (race and ethnicity, relationship status, and sexual orientation).
Other category includes Asian, Native Hawaiian or Pacific Islander, American Indian or Alaska Native, African American or Black, and other.
Other category includes divorced or separated, widowed, and other.
Other category includes any category besides exclusively heterosexual.
Contraceptive users’ experiences of methods over three months: ordinal variables, sample of family-planning clients using a new contraceptive method for three months (N = 3,762 observations).
| Overall ( | Implant ( | Copper IUD ( | LNg IUD ( | Injectable ( | Oral Contraceptives ( | Vaginal Ring ( | ||
|---|---|---|---|---|---|---|---|---|
| % | % | % | % | % | % | % | ||
| In the last four weeks, would you say that your birth control method has: | ||||||||
| Made my sex life much worse | 2.3 | 2.8 | 2.1 | 2.2 | 4.0 | 1.2 | 1.4 | |
| Made my sex life a little worse | 12.4 | 11.2 | 10.7 | 15.2 | 14.8 | 8.4 | 13.7 | |
| Had no effect on my sex life | 33.9 | 33.8 | 29.0 | 30.6 | 40.1 | 39.7 | 43.8 | |
| Improved my sex life a little | 25.7 | 24.4 | 27.6 | 27.1 | 19.9 | 27.0 | 24.0 | |
| Improved my sex life a lot | 25.7 | 27.8 | 30.6 | 25.0 | 21.2 | 23.7 | 17.1 | |
| Which of the following best describes your vaginal bleeding in the last four weeks? | ||||||||
| I’ve had no vaginal bleeding | 16.2 | 22.2 | 5.9 | 10.9 | 41.7 | 10.3 | 19.9 | |
| I’ve had less bleeding than before | 32.4 | 30.6 | 12.6 | 43.3 | 24.2 | 38.3 | 30.1 | |
| I’ve had no change from before | 13.5 | 9.9 | 14.9 | 7.9 | 6.2 | 28.4 | 34.9 | |
| I’ve had more bleeding than before | 38.0 | 37.3 | 66.6 | 37.8 | 28.0 | 23.0 | 15.1 |
Note. Frequencies reflect pooled distributions of variables at one- and three-month follow-up surveys. Data presented are for complete cases in the later regression model, and percentages indicate the column proportion for the specific variable. Descriptive data are presented on the nonimputed original data set. Some columns may add to slightly less than or greater than 100%; these summations are due to rounding errors. P values reflect comparison of outcome by contraceptive methods using the Skillings–Mack statistic, conditional on tied rankings; LNg = levonorgestrel; IUD = intrauterine device.
Changes in contraceptive users’ experiences of methods over three months: continuous variables, sample of family-planning clients using a new contraceptive method for three months (N = 1,881 observations).
| Overall ( | Implant ( | Copper IUD ( | LNg IUD ( | Injectable ( | Oral Contraceptives ( | Vaginal Ring ( | ||
|---|---|---|---|---|---|---|---|---|
| Change in New Sexual Satisfaction Scale (scale 20–100, where a higher score indicates better sexual satisfaction)[ | −.8 ±8.7 | −1.3 ±8.3 | .06 ±8.2 | −1.2 ±9.0 | −.6 ±9.1 | −.5 ±8.6 | −.4 ±10.2 | |
| Change in FSFI-6 (scale 5–30, where a higher score indicates better sexual function)[ | −.1 ±2.8 | −.4 ±2.7 | .1 ±2.4 | .07 ±2.8 | −.8 ±2.9 | −.03 ±3.0 | −.05 ±3.3 | |
| Menstrual Symptom Questionnaire: change in average experience and frequency of physical side effects (scale 0–5, where 5 represents highest frequency; symptoms include headaches, bloating, breast tenderness, acne flare-up, cramping, weight gain, weight loss, and gastrointestinal symptoms) | .1 ±.4 | .1 ±.4 | .1 ±.4 | .09 ±.4 | .2 ±.5 | .08 ±.4 | .08 ±.5 | |
| Menstrual Symptom Questionnaire: change in average experience and frequency of mood side effects (scale 0–5, where 5 represents highest frequency; symptoms include moodiness or irritability and depression) | .1 ±.7 | .3 ±.7 | −.003 ±.6 | .07 ±.7 | .3 ±.8 | .1 ±.7 | .00 ±.6 | |
| Change in WHO Well-Being Scale (scale 0–25, where a higher score indicates better overall health and well-being) | −.4 ±2.6 | −.7 ±2.7 | −.3 ±2.4 | −.2 ±2.5 | −.9 ±2.8 | −.5 ±2.4 | −.2 ±2.3 |
Note. Frequencies reflect average change in variables from baseline to one-month follow-up, and from one-month to three-month follow-up at the respondent level. Data presented are for complete cases in the later regression model. Descriptive data are presented on the nonimputed original data set. F values and p values compare outcome by contraceptive method using one-way analyses of variance (df = 5); ; LNg = levonorgestrel; IUD = intrauterine device.
Sample size for this item was 1,595 observations.
Sample size for this item was 1,741 observations.
Ordered, multilevel, logistic regression odds ratios predicting association between covariates and family-planning clients’ reported impact of method on sex life, one to three months after enrollment (N = 3,762 observations).
| Adjusted Odds Ratio | Confidence Interval | Level of Significance | |
|---|---|---|---|
| Baseline method | |||
| Oral contraceptives (reference) | — | — | — |
| Implant | 1.19 | (.95–1.50) | |
| Copper IUD |
| (1.45–2.44) |
|
| LNg IUD | 1.15 | (.92–1.42) | |
| Three-month injectable |
| (.55–.98) |
|
| Vaginal ring | .82 | (.59–.1.15) | |
| Bleeding changes | |||
| I’ve had no vaginal bleeding |
| (1.09–1.71) |
|
| I’ve had less bleeding than before |
| (1.18–1.74) |
|
| I’ve had no change from before (reference) | — | — | — |
| I’ve had more bleeding than before |
| (.63–.94) |
|
| Menstrual Symptom Questionnaire: Physical side effects (scale 0–5) |
| (.69–.86) |
|
| Menstrual Symptom Questionnaire: Mood side effects (scale 0–5) | .99 | (.92–1.06) | |
| WHO-5 Well-Being Scale (scale 0–25) |
| (1.06–1.09) |
|
| Age | |||
| 18–19 (reference) | — | — | — |
| 20–24 |
| (.65–.97) |
|
| 25–29 |
| (.58–.94) |
|
| 30–34 |
| (.40–.74) |
|
| 35 and older |
| (.43–.86) |
|
| Highest level of education completed | |||
| Did not complete high school (reference) | — | — | — |
| High school or GED | .96 | (.67–1.37) | |
| Some associate, vocational, technical training, or college | .88 | (.61–1.28) | |
| Completed four-year college or higher | .85 | (.57–1.28) | |
| Race and ethnicity | |||
| Non-Hispanic White (reference) | — | — | — |
| Hispanic non-White | .87 | (.72–1.06) | |
| Non-White, non-Hispanic other | 1.21 | (.95–1.54) | |
| Poverty category | |||
| At or below poverty level (reference) | — | — | — |
| 101%–199% above poverty level | 1.00 | (.84–1.21) | |
| 200%–299% above poverty level | 1.01 | (.81–1.25) | |
| 300% or more above poverty level | .95 | (.74–1.22) | |
| Relationship status | |||
| Married (reference) | — | — | — |
| Cohabiting or committed relationship | 1.14 | (.90–1.45) | |
| Actively dating | 1.24 | (.94–1.64) | |
| Single |
| (.56–.99) |
|
| Other | 1.20 | (.82–1.78) | |
| Sexual orientation | |||
| Heterosexual or mostly heterosexual (reference) | — | — | — |
| Other | 1.04 | (.83–1.30) | |
| Study-related fixed controls: enrollment site, study period, wave | ✔ | ||
| Individual fixed controls: number of bleeding days, interval between surveys | ✔ | ||
|
| 51 | ||
|
| 3,762 |
Note. LNg = levonorgestrel; IUD = intrauterine device. The bold value corresponds to odds ratio that are statistically significant at the p < .05 level.