BACKGROUND: Depot medroxyprogesterone acetate (DMPA) may have other noncontraceptive effects that could impact on the quality of life. The objective of this study was to assess the health-related quality of life changes associated with the use of DMPA for contraception. STUDY DESIGN: A prospective, observational study using the Short Form-36 quality of life questionnaire. RESULTS: After 6 months of use, the participants had an improved physical summary score, mean change [5.64 (95% confidence interval [CI], 1.87-9.4), p=.054]. There was no significant change in sexual function [5.33 (95% CI, -2.15 to 12.81), p=.0858] and mental summary score [-0.51 (95% CI, -1.90 to 2.92), p=.432]. The main side effect of DMPA was menstrual irregularity (32.5%); 17.2% of the participants found amenorrhea desirable. CONCLUSION: Besides its contraceptive efficacy, DMPA is associated with an improvement in perceived physical health with no apparent adverse effect on mental health and sexual function.
BACKGROUND: Depot medroxyprogesterone acetate (DMPA) may have other noncontraceptive effects that could impact on the quality of life. The objective of this study was to assess the health-related quality of life changes associated with the use of DMPA for contraception. STUDY DESIGN: A prospective, observational study using the Short Form-36 quality of life questionnaire. RESULTS: After 6 months of use, the participants had an improved physical summary score, mean change [5.64 (95% confidence interval [CI], 1.87-9.4), p=.054]. There was no significant change in sexual function [5.33 (95% CI, -2.15 to 12.81), p=.0858] and mental summary score [-0.51 (95% CI, -1.90 to 2.92), p=.432]. The main side effect of DMPA was menstrual irregularity (32.5%); 17.2% of the participants found amenorrhea desirable. CONCLUSION: Besides its contraceptive efficacy, DMPA is associated with an improvement in perceived physical health with no apparent adverse effect on mental health and sexual function.
Authors: Kevin McKenna; Jennet Arcara; Kate H Rademacher; Caroline Mackenzie; Fidele Ngabo; Emmanuel Munyambanza; Jennifer Wesson; Elizabeth E Tolley Journal: Glob Health Sci Pract Date: 2014-10-15
Authors: Mohammad S Alyahya; Heba H Hijazi; Hussam A Alshraideh; Nihaya A Al-Sheyab; Dana Alomari; Sara Malkawi; Sarah Qassas; Samah Darabseh; Yousef S Khader Journal: Health Qual Life Outcomes Date: 2019-10-15 Impact factor: 3.186