Literature DB >> 33549100

A compositional analysis of time spent in sleep, sedentary behaviour and physical activity with all-cause mortality risk.

Anna E Clarke1, Ian Janssen2,3.   

Abstract

BACKGROUND: Daily time spent in sleep, sedentary behaviour (SED), light intensity physical activity (LIPA), and moderate-to-vigorous intensity physical activity (MVPA) are compositional, co-dependent variables. The objectives of this study were to use compositional data analysis to: (1) examine the relationship between the movement behaviour composition (daily time spent in sleep, SED, LIPA and MVPA) and all-cause mortality risk, and (2) estimate the extent to which changing time spent in any given movement behaviour (sleep, SED, LIPA, or MVPA) within the movement behaviour composition was associated with changes in risk of all-cause mortality.
METHODS: 2838 adult participants from the 2005-2006 cycle of the U.S. National Health and Nutrition Examination Survey were studied using a prospective cohort design. Daily time spent in SED, LIPA and MVPA were determined by accelerometer. Nightly time spent sleeping was self-reported. Survey data were linked with mortality data through to the end of December 2015. Compositional data analysis was used to investigate relationships between the movement behaviour composition and mortality.
RESULTS: The movement behaviour composition was significantly associated with mortality risk. Time spent in MVPA relative to other movement behaviours was negatively associated with mortality risk (HR = .74; 95% CI [.67, .83]) while relative time spent in SED was positively associated with mortality risk (HR = 1.75; 95% CI [1.10, 2.79]). Time displacement estimates revealed that the greatest estimated changes in mortality risk occurred when time spent in MVPA was decreased and replaced with sleep, SED, LIPA or a combination of these behaviours (HRs of 1.76 to 1.80 for 15 min/day displacements).
CONCLUSIONS: The daily movement behaviour composition was related to mortality. Replacing time in MVPA or SED with equivalent time from any other movement behaviour was associated with an increase and decrease in mortality risk, respectively.

Entities:  

Keywords:  24-h movement behaviours; Compositional data analysis; Physical activity; Public health; Sedentary behaviour; Sleep; Survival analysis

Mesh:

Year:  2021        PMID: 33549100      PMCID: PMC7866642          DOI: 10.1186/s12966-021-01092-0

Source DB:  PubMed          Journal:  Int J Behav Nutr Phys Act        ISSN: 1479-5868            Impact factor:   8.915


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