Chang Liu1, Yi-Ping Feng2, Zi-Ning Yan1, Li Fan1, Yi-Fei Rui1, Ling Cui1. 1. Department of Echocardiography, The Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou, 213003, China. 2. Department of Echocardiography, The Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou, 213003, China. cccc5288@qq.com.
Abstract
BACKGROUND: This study aimed to determine the left ventricular (LV) systolic function in patients on maintenance hemodialysis (MHD) using the myocardial work (MW) technique and investigate the clinical value of the MW technique for the quantitative analysis of left ventricular (LV) systolic function in MHD patients with left ventricular hypertrophy (LVH). METHODS: A total of 68 MHD patients and 35 controls were registered in this study. The MHD patients were divided into the non-left ventricular hypertrophy (NLVH) group (n = 35) and the LVH group (n = 33) according to the LV mass index (LVMI). MW was used to generate the LV global longitudinal strain (GLS), global work index (GWI), global constructive work (GCW), and global wasted work (GWW), global work efficiency (GWE). GLS and the MW parameters (GWI, GCW, GWW, GWE) were compared between groups and the correlations between these parameters and the LV ejection fraction (LVEF) in the LVH group were examined. The receiver operating characteristic (ROC) curve was used to evaluate the efficacy of MW parameters and GLS for the assessment of LV systolic dysfunction in MHD with LVH patients. RESULTS: The LVH group had significantly lower GWE, GWI, GCW, and GLS but higher GWW than the control and NLVH groups. Compared with the control group, the NLVH group had significantly lower GWE and GLS and higher GWW, but no significant differences in GWI, GCW were observed between these two groups. The LVEF was negatively correlated with GWW in MHD patients, but positively correlated with GWI, GWE, and GCW in the LVH group. Receiver operating characteristic curve (ROC) analysis revealed that GWE, GWW, GWI, and GCW had appreciable area under the curve (AUC), sensitivity, and specificity for evaluating LV function in LVH patients on MHD. CONCLUSIONS: The MW parameters can quantitatively represent the LV myocardial work in MHD patients. Thus, the technique provides a new method for the quantitative evaluation of LV systolic function in MHD with LVH patients.
BACKGROUND: This study aimed to determine the left ventricular (LV) systolic function in patients on maintenance hemodialysis (MHD) using the myocardial work (MW) technique and investigate the clinical value of the MW technique for the quantitative analysis of left ventricular (LV) systolic function in MHD patients with left ventricular hypertrophy (LVH). METHODS: A total of 68 MHD patients and 35 controls were registered in this study. The MHD patients were divided into the non-left ventricular hypertrophy (NLVH) group (n = 35) and the LVH group (n = 33) according to the LV mass index (LVMI). MW was used to generate the LV global longitudinal strain (GLS), global work index (GWI), global constructive work (GCW), and global wasted work (GWW), global work efficiency (GWE). GLS and the MW parameters (GWI, GCW, GWW, GWE) were compared between groups and the correlations between these parameters and the LV ejection fraction (LVEF) in the LVH group were examined. The receiver operating characteristic (ROC) curve was used to evaluate the efficacy of MW parameters and GLS for the assessment of LV systolic dysfunction in MHD with LVH patients. RESULTS: The LVH group had significantly lower GWE, GWI, GCW, and GLS but higher GWW than the control and NLVH groups. Compared with the control group, the NLVH group had significantly lower GWE and GLS and higher GWW, but no significant differences in GWI, GCW were observed between these two groups. The LVEF was negatively correlated with GWW in MHD patients, but positively correlated with GWI, GWE, and GCW in the LVH group. Receiver operating characteristic curve (ROC) analysis revealed that GWE, GWW, GWI, and GCW had appreciable area under the curve (AUC), sensitivity, and specificity for evaluating LV function in LVH patients on MHD. CONCLUSIONS: The MW parameters can quantitatively represent the LV myocardial work in MHD patients. Thus, the technique provides a new method for the quantitative evaluation of LV systolic function in MHD with LVH patients.
Entities:
Keywords:
Echocardiography; Left ventricular hypertrophy; Maintenance hemodialysis; Myocardial work; Systolic function
Authors: Pieter van der Bijl; Marina Kostyukevich; Mohammed El Mahdiui; Gunnar Hansen; Eigil Samset; Nina Ajmone Marsan; Jeroen J Bax; Victoria Delgado Journal: JACC Cardiovasc Imaging Date: 2019-07-17
Authors: Ruth Lagies; Bodo B Beck; Bernd Hoppe; Sahar S Sheta; Verena Weiß; Narayanswami Sreeram; Floris E A Udink ten Cate Journal: Echocardiography Date: 2014-12-01 Impact factor: 1.724
Authors: Roberta Manganaro; Stella Marchetta; Raluca Dulgheru; Federica Ilardi; Tadafumi Sugimoto; Sébastien Robinet; Sara Cimino; Yun Yun Go; Anne Bernard; George Kacharava; George D Athanassopoulos; Daniele Barone; Monica Baroni; Nuno Cardim; Andreas Hagendorff; Krasimira Hristova; Teresa López-Fernández; Gonzalo de la Morena; Bogdan A Popescu; Martin Penicka; Tolga Ozyigit; Jose David Rodrigo Carbonero; Nico van de Veire; Ralph Stephan Von Bardeleben; Dragos Vinereanu; Jose Luis Zamorano; Monica Rosca; Andreea Calin; Marie Moonen; Julien Magne; Bernard Cosyns; Elena Galli; Erwan Donal; Scipione Carerj; Concetta Zito; Ciro Santoro; Maurizio Galderisi; Luigi P Badano; Roberto M Lang; Cecile Oury; Patrizio Lancellotti Journal: Eur Heart J Cardiovasc Imaging Date: 2019-05-01 Impact factor: 6.875
Authors: Ashwin Radhakrishnan; Luke C Pickup; Anna M Price; Jonathan P Law; Nicola C Edwards; Richard P Steeds; Charles J Ferro; Jonathan N Townend Journal: Heart Date: 2019-06-25 Impact factor: 5.994