Literature DB >> 33546219

The Role of Hypothalamic Inflammation in Diet-Induced Obesity and Its Association with Cognitive and Mood Disorders.

Sofia Dionysopoulou1, Evangelia Charmandari2,3, Alexandra Bargiota4, Nikolaos Vlahos5, George Mastorakos6, Georgios Valsamakis4,6.   

Abstract

Obesity is often associated with cognitive and mood disorders. Recent evidence suggests that obesity may cause hypothalamic inflammation. Our aim was to investigate the hypothesis that there is a causal link between obesity-induced hypothalamic inflammation and cognitive and mood disorders. Inflammation may influence hypothalamic inter-connections with regions important for cognition and mood, while it may cause dysregulation of the Hypothalamic-Pituitary-Adrenal (HPA) axis and influence monoaminergic systems. Exercise, healthy diet, and glucagon-like peptide receptor agonists, which can reduce hypothalamic inflammation in obese models, could improve the deleterious effects on cognition and mood.

Entities:  

Keywords:  cognitive disorders; dementia; depression; diet; hypothalamic inflammation; mood disorders; obesity

Mesh：

Substances：

Year:  2021        PMID： 33546219      PMCID： PMC7913301          DOI： 10.3390/nu13020498

Source DB:  PubMed          Journal:  Nutrients        ISSN： 2072-6643            Impact factor:   5.717


  197 in total

Review 1.  Role of glucocorticoids in the regulation of dopaminergic neurotransmission.

Authors:  Anna Czyrak; Marzena Maćkowiak; Agnieszka Chocyk; Katarzyna Fijał; Krzystof Wedzony
Journal:  Pol J Pharmacol       Date:  2003 Sep-Oct

Review 2.  Role of GABA and glutamate circuitry in hypothalamo-pituitary-adrenocortical stress integration.

Authors:  James P Herman; Nancy K Mueller; Helmer Figueiredo
Journal:  Ann N Y Acad Sci       Date:  2004-06       Impact factor: 5.691

Review 3.  Intergenerational Transmission of Stress in Humans.

Authors:  Mallory E Bowers; Rachel Yehuda
Journal:  Neuropsychopharmacology       Date:  2015-08-17       Impact factor: 7.853

4.  Variations of nucleus accumbens dopamine and serotonin following systemic interleukin-1, interleukin-2 or interleukin-6 treatment.

Authors:  C Song; Z Merali; H Anisman
Journal:  Neuroscience       Date:  1999       Impact factor: 3.590

5.  Nox2-derived superoxide contributes to cerebral vascular dysfunction in diet-induced obesity.

Authors:  Cynthia M Lynch; Dale A Kinzenbaw; Xunxheng Chen; Shanshan Zhan; Erin Mezzetti; Jessica Filosa; Adviye Ergul; Jessica L Faulkner; Frank M Faraci; Sean P Didion
Journal:  Stroke       Date:  2013-09-26       Impact factor: 7.914

Review 6.  Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association.

Authors:  Philip B Gorelick; Angelo Scuteri; Sandra E Black; Charles Decarli; Steven M Greenberg; Costantino Iadecola; Lenore J Launer; Stephane Laurent; Oscar L Lopez; David Nyenhuis; Ronald C Petersen; Julie A Schneider; Christophe Tzourio; Donna K Arnett; David A Bennett; Helena C Chui; Randall T Higashida; Ruth Lindquist; Peter M Nilsson; Gustavo C Roman; Frank W Sellke; Sudha Seshadri
Journal:  Stroke       Date:  2011-07-21       Impact factor: 7.914

7.  Western diet, obesity and bariatric surgery sequentially modulated anxiety, eating patterns and brain responses to sucrose in adult Yucatan minipigs.

Authors:  Yentl Gautier; Damien Bergeat; Yann Serrand; Noémie Réthoré; Mathilde Mahérault; Charles-Henri Malbert; Paul Meurice; Nicolas Coquery; Romain Moirand; David Val-Laillet
Journal:  Sci Rep       Date:  2020-11-18       Impact factor: 4.379

8.  Obese-type gut microbiota induce neurobehavioral changes in the absence of obesity.

Authors:  Annadora J Bruce-Keller; J Michael Salbaum; Meng Luo; Eugene Blanchard; Christopher M Taylor; David A Welsh; Hans-Rudolf Berthoud
Journal:  Biol Psychiatry       Date:  2014-07-18       Impact factor: 13.382

9.  Impairment of hippocampal-dependent memory induced by juvenile high-fat diet intake is associated with enhanced hippocampal inflammation in rats.

Authors:  Chloé Boitard; Amandine Cavaroc; Julie Sauvant; Agnès Aubert; Nathalie Castanon; Sophie Layé; Guillaume Ferreira
Journal:  Brain Behav Immun       Date:  2014-03-22       Impact factor: 7.217

Review 10.  Association of anthropometry and weight change with risk of dementia and its major subtypes: A meta-analysis consisting 2.8 million adults with 57 294 cases of dementia.

Authors:  Crystal ManYing Lee; Mark Woodward; G David Batty; Alexa S Beiser; Steven Bell; Claudine Berr; Espen Bjertness; John Chalmers; Robert Clarke; Jean-Francois Dartigues; Kendra Davis-Plourde; Stéphanie Debette; Emanuele Di Angelantonio; Catherine Feart; Ruth Frikke-Schmidt; John Gregson; Mary N Haan; Linda B Hassing; Kathleen M Hayden; Marieke P Hoevenaar-Blom; Jaakko Kaprio; Mika Kivimaki; Georgios Lappas; Eric B Larson; Erin S LeBlanc; Anne Lee; Li-Yung Lui; Eric P Moll van Charante; Toshiharu Ninomiya; Liv Tybjaerg Nordestgaard; Tomoyuki Ohara; Toshiaki Ohkuma; Teemu Palviainen; Karine Peres; Ruth Peters; Nawab Qizilbash; Edo Richard; Annika Rosengren; Sudha Seshadri; Martin Shipley; Archana Singh-Manoux; Bjorn Heine Strand; Willem A van Gool; Eero Vuoksimaa; Kristine Yaffe; Rachel R Huxley
Journal:  Obes Rev       Date:  2020-01-03       Impact factor: 9.213
View more
  11 in total

1.  Anxiety-like behavior and microglial activation in the amygdala after acute neuroinflammation induced by microbial neuraminidase.

Authors:  Ana León-Rodríguez; María Del Mar Fernández-Arjona; Jesús M Grondona; Carmen Pedraza; María D López-Ávalos
Journal:  Sci Rep       Date:  2022-07-08       Impact factor: 4.996

2.  Association of Dietary Inflammatory Index (DII) and depression in the elderly over 55 years in Northern China: analysis of data from a multicentre, cohort study.

Authors:  Ruiqiang Li; Wenqiang Zhan; Xin Huang; Zechen Zhang; Meiqi Zhou; Wei Bao; Feifei Huang; Yuxia Ma
Journal:  BMJ Open       Date:  2022-04-21       Impact factor: 3.006

3.  Sugar-Sweetened Beverages and Depressive and Social Anxiety Symptoms Among Children and Adolescents Aged 7-17 Years, Stratified by Body Composition.

Authors:  Jieyu Liu; Ting Chen; Manman Chen; Ying Ma; Tao Ma; Di Gao; Yanhui Li; Qi Ma; Li Chen; Xinxin Wang; Yi Zhang; Jun Ma; Yanhui Dong
Journal:  Front Nutr       Date:  2022-05-23

4.  The Relationship Between Mild Cognitive Impairment and Anti-Inflammatory/Pro-Inflammatory Nutrients in the Elderly in Northern China: A Bayesian Kernel Machine Regression Approach.

Authors:  Ruiqiang Li; Wenqiang Zhan; Xin Huang; Limin Zhang; Zechen Zhang; Meiqi Zhou; Zhihong Wang; Yuxia Ma
Journal:  J Inflamm Res       Date:  2022-01-14

Review 5.  Aberrant Feeding and Growth in Neonates With Prenatal Opioid Exposure: Evidence of Neuromodulation and Behavioral Changes.

Authors:  Elizabeth Yen; Jill L Maron
Journal:  Front Pediatr       Date:  2022-01-21       Impact factor: 3.418

6.  Donor bone marrow-derived macrophage MHC II drives neuroinflammation and altered behavior during chronic GVHD in mice.

Authors:  Rachael C Adams; Dylan Carter-Cusack; Samreen N Shaikh; Genesis T Llanes; Rebecca L Johnston; Gregory Quaife-Ryan; Glen Boyle; Lambros T Koufariotis; Andreas Möller; Bruce R Blazar; Jana Vukovic; Kelli P A MacDonald
Journal:  Blood       Date:  2022-03-03       Impact factor: 25.476

Review 7.  The molecular signaling of exercise and obesity in the microbiota-gut-brain axis.

Authors:  Filipe M Ribeiro; Maycon A Silva; Victória Lyssa; Gabriel Marques; Henny K Lima; Octavio L Franco; Bernardo Petriz
Journal:  Front Endocrinol (Lausanne)       Date:  2022-07-28       Impact factor: 6.055

Review 8.  The Impact of Obesity on Microglial Function: Immune, Metabolic and Endocrine Perspectives.

Authors:  Vasileia Ismini Alexaki
Journal:  Cells       Date:  2021-06-23       Impact factor: 6.600

Review 9.  Metabolic Syndrome, Cognitive Impairment and the Role of Diet: A Narrative Review.

Authors:  Matina Kouvari; Nathan M D'Cunha; Nikolaj Travica; Domenico Sergi; Manja Zec; Wolfgang Marx; Nenad Naumovski
Journal:  Nutrients       Date:  2022-01-13       Impact factor: 5.717

Review 10.  Anti-Inflammatory Nutrients and Obesity-Associated Metabolic-Inflammation: State of the Art and Future Direction.

Authors:  Giuseppe Grosso; Daniela Laudisio; Evelyn Frias-Toral; Luigi Barrea; Giovanna Muscogiuri; Silvia Savastano; Annamaria Colao
Journal:  Nutrients       Date:  2022-03-08       Impact factor: 5.717
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.