Literature DB >> 33528708

End-of-Life Hospice Use and Medicare Expenditures Among Patients Dying of Hepatocellular Carcinoma.

Daniel R Rice1, J Madison Hyer1, Adrian Diaz1, Timothy M Pawlik2.   

Abstract

BACKGROUND: The increasing incidence of hepatocellular carcinoma (HCC) coupled with rising health care costs contributes to high end-of-life expenditures. The current study aimed to characterize health care expenditures and hospice use among patients with HCC using a large, national database.
METHODS: The Surveillance, Epidemiology, and End Results (SEER)-Medicare-linked database was used to identify patients with HCC. Logistic regression was used to identify factors associated with overall hospice use and end-of-life expenditures among individuals who died of HCC.
RESULTS: Among 14,369 Medicare beneficiaries with HCC, 8069 (63.7 %) used hospice. Racial/ethnic minority patients were less likely to use hospice services during the last year of life than white patients (no hospice: n = 2034 [44.3 %] vs. hospice: n = 2513 [31.1 %]). Social vulnerability also had an impact on the likelihood of patients using hospice services; in particular, the probability of hospice use among patients declined as social vulnerability increased (P < 0.05). Hospice use was associated with an approximate $10,000 decrease in inpatient expenditures (hospice: US$7900 [IQR, US$0-26,600] vs. no hospice: US$18,000 [IQR $400-49,100]; P < 0.001) and $1300 decrease in outpatient expenditures (hospice: US$900 [IQR, US$0-4500] vs. non-hospice: US$2200 [IQR, US$200-7900; P < 0.001) compared with individuals who did not use hospice.
CONCLUSIONS: Minority patients and individuals residing in high-vulnerability areas were less likely to use hospice. Patients who used hospice at the end of life had a reduction in inpatient and outpatient Medicare claims. Patients with HCC in need of hospice services should be ensured timely referral regardless of race/ethnicity or social vulnerability.
© 2021. Society of Surgical Oncology.

Entities:  

Year:  2021        PMID: 33528708     DOI: 10.1245/s10434-021-09606-7

Source DB:  PubMed          Journal:  Ann Surg Oncol        ISSN: 1068-9265            Impact factor:   5.344


  22 in total

1.  Updating and validating the Charlson comorbidity index and score for risk adjustment in hospital discharge abstracts using data from 6 countries.

Authors:  Hude Quan; Bing Li; Chantal M Couris; Kiyohide Fushimi; Patrick Graham; Phil Hider; Jean-Marie Januel; Vijaya Sundararajan
Journal:  Am J Epidemiol       Date:  2011-02-17       Impact factor: 4.897

Review 2.  Diagnosis and treatment of hepatocellular carcinoma: An update.

Authors:  Javier Tejeda-Maldonado; Ignacio García-Juárez; Jonathan Aguirre-Valadez; Adrián González-Aguirre; Mario Vilatobá-Chapa; Alejandra Armengol-Alonso; Francisco Escobar-Penagos; Aldo Torre; Juan Francisco Sánchez-Ávila; Diego Luis Carrillo-Pérez
Journal:  World J Hepatol       Date:  2015-03-27

3.  Disparities in hospice care among older women dying with ovarian cancer.

Authors:  Kathleen M Fairfield; Kimberly M Murray; Heidi R Wierman; Paul K J Han; Sarah Hallen; Susan Miesfeldt; Edward L Trimble; Joan L Warren; Craig C Earle
Journal:  Gynecol Oncol       Date:  2011-12-01       Impact factor: 5.482

4.  Comparison of Site of Death, Health Care Utilization, and Hospital Expenditures for Patients Dying With Cancer in 7 Developed Countries.

Authors:  Justin E Bekelman; Scott D Halpern; Carl Rudolf Blankart; Julie P Bynum; Joachim Cohen; Robert Fowler; Stein Kaasa; Lukas Kwietniewski; Hans Olav Melberg; Bregje Onwuteaka-Philipsen; Mariska Oosterveld-Vlug; Andrew Pring; Jonas Schreyögg; Connie M Ulrich; Julia Verne; Hannah Wunsch; Ezekiel J Emanuel
Journal:  JAMA       Date:  2016-01-19       Impact factor: 56.272

5.  Cancer's next frontier: addressing high and increasing costs.

Authors:  Elena B Elkin; Peter B Bach
Journal:  JAMA       Date:  2010-03-17       Impact factor: 56.272

6.  Cancer treatment cost in the United States: has the burden shifted over time?

Authors:  Florence K Tangka; Justin G Trogdon; Lisa C Richardson; David Howard; Susan A Sabatino; Eric A Finkelstein
Journal:  Cancer       Date:  2010-07-15       Impact factor: 6.860

7.  Health expenditures and financial burden among patients with major gastrointestinal cancers relative to other common cancers in the United States.

Authors:  Daniel R Rice; Ayesha Farooq; J Madison Hyer; Anghela Z Paredes; Junu Bae; Diamantis I Tsilimigras; Timothy M Pawlik
Journal:  Surgery       Date:  2020-04-15       Impact factor: 3.982

8.  The Cost of Hospice Services in Terminally Ill Patients With Head and Neck Cancer.

Authors:  Laura M Enomoto; Eric W Schaefer; David Goldenberg; Heath Mackley; Wayne M Koch; Christopher S Hollenbeak
Journal:  JAMA Otolaryngol Head Neck Surg       Date:  2015-12       Impact factor: 6.223

Review 9.  Hepatocellular carcinoma: a review.

Authors:  Julius Balogh; David Victor; Emad H Asham; Sherilyn Gordon Burroughs; Maha Boktour; Ashish Saharia; Xian Li; R Mark Ghobrial; Howard P Monsour
Journal:  J Hepatocell Carcinoma       Date:  2016-10-05

10.  Surveillance and diagnosis of hepatocellular carcinoma: A systematic review.

Authors:  Sonia Pascual; Cayetano Miralles; Juan M Bernabé; Javier Irurzun; Mariana Planells
Journal:  World J Clin Cases       Date:  2019-08-26       Impact factor: 1.337

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  1 in total

1.  Caryophyllene Oxide Induces Ferritinophagy by Regulating the NCOA4/FTH1/LC3 Pathway in Hepatocellular Carcinoma.

Authors:  Zhiru Xiu; Yilong Zhu; Jicheng Han; Yaru Li; Xia Yang; Guohua Yang; Gaojie Song; Shanzhi Li; Yue Li; Cheng Cheng; Yiquan Li; Jinbo Fang; Xiao Li; Ningyi Jin
Journal:  Front Pharmacol       Date:  2022-07-11       Impact factor: 5.988

  1 in total

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