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Literature DB >> 33528009

Variability in Ceftriaxone Dosing Across 32 US Acute Care Children's Hospitals.

Rina A Ferguson¹, Joshua C Herigon², Brian R Lee³, Mari M Nakamura^2,4, Jason G Newland¹.

Abstract

Ceftriaxone is one of the most common antibiotics prescribed for hospitalized children in the United States. However, ceftriaxone is not dosed consistently. Sepsis/serious bacterial infection had high dosing variability. Dosing for central nervous system infection was frequently suboptimal. Future efforts should focus on optimizing and standardizing ceftriaxone dosing.

© The Author(s) 2021. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Entities: Chemical

Keywords: antibiotic dosing; ceftriaxone; inpatient antimicrobial stewardship; therapeutic dosing; weight-based dosing

Mesh：

Substances：

Year: 2021 PMID： 33528009 PMCID： PMC8163046 DOI： 10.1093/jpids/piab004

Source DB: PubMed Journal: J Pediatric Infect Dis Soc ISSN： 2048-7193 Impact factor: 3.164

Keyword Cloud
References

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Variability in Ceftriaxone Dosing Across 32 US Acute Care Children's Hospitals.

1. Variability in antibiotic use at children's hospitals.

2. Variability in Antibiotic Regimens for Surgical Necrotizing Enterocolitis Highlights the Need for New Guidelines.

3. Pharmacokinetics of ceftriaxone in pediatric patients with meningitis.

4. Variability in Antibiotic Use Across PICUs.

5. The REDCap consortium: Building an international community of software platform partners.

6. Considerable variability in antibiotic use among US children's hospitals in 2017-2018.

7. Appropriateness of Antibiotic Prescribing in United States Children's Hospitals: A National Point Prevalence Survey.

8. Sharing Antimicrobial Reports for Pediatric Stewardship (SHARPS): A Quality Improvement Collaborative.