Literature DB >> 33527046

Tea in the Morning and Khat Afternoon: Health Threats Due to Khat Chewing.

Iana Malasevskaia1,2, Ahmed A Al-Awadhi3, Lubna Mohammed4.   

Abstract

Khat or qat (Catha edulis) is a flowering plant with an Arabic name قات, regularly named as qāt, also is known by various descriptive names, such as Abyssinian tea, Somali tea, Arabian tea, Miraa, Jima, and Kafta in its endemic regions of the Horn of Africa and the Arabian Peninsula. Fresh leaves and tops of khat are chewed or dried and consumed as a tea to attain a state of euphoria and excitement; it also has appetite-reducing effects. Traditionally, khat is used as a socializing habit in Yemen and is also widely cultivated because of its high income. However, in recent years the plant has been reported in England, Wales, Rome, Amsterdam, Canada, Israel, Australia, New Zealand, and the United States. Although it is believed that khat is a relatively low-risk drug, it's associated with an increased risk for various medical complications, including dental and oropharyngeal disease, gastrointestinal, cardiovascular, neuropsychiatric, obstetric, and even can be the cause of cancer. Our goal in this review article is to revise and determine the relationship between chewing khat and its health issues. Additionally, we tried to determine the mechanism involved in health hazards due to consuming the khat.
Copyright © 2020, Malasevskaia et al.

Entities:  

Keywords:  amphetamine-like plant; catha edulis; cathine; cathinone; chewing khat; effects on general health; health hazards; khat; khat and health impact; khat and liver disease

Year:  2020        PMID: 33527046      PMCID: PMC7842844          DOI: 10.7759/cureus.12363

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  29 in total

1.  Reversible khat-induced hepatitis: two case reports and review of the literature.

Authors:  M G Jenkins; R Handslip; M Kumar; U Mahadeva; S Lucas; T Yamamoto; D M Wood; T Wong; P I Dargan
Journal:  Frontline Gastroenterol       Date:  2013-05-10

2.  Short-term effects of high-dose khat on sperm parameters and reproductive hormonal levels in olive baboons (Papio anubis).

Authors:  Atunga Nyachieo; Muthamia M Kiraithe; Carl Spiessens; Daniel C Chai; Nicholas M Kiulia; Thomas M D'Hooghe; Jason M Mwenda
Journal:  Gynecol Obstet Invest       Date:  2012-12-11       Impact factor: 2.031

Review 3.  Overview of literature and information on "khat-related" mortality: a call for recognition of the issue and further research.

Authors:  John M Corkery; Fabrizio Schifano; Adenekan Oyefeso; A Hamid Ghodse; Thomy Tonia; Vinesha Naidoo; Jennifer Button
Journal:  Ann Ist Super Sanita       Date:  2011       Impact factor: 1.663

4.  Use of khat in lactating women: a pilot study on breast-milk secretion.

Authors:  B Kristiansson; N Abdul Ghani; M Eriksson; M Garle; A Qirbi
Journal:  J Ethnopharmacol       Date:  1987 Sep-Oct       Impact factor: 4.360

5.  Influence of Khat Chewing on Periodontal Tissues and Oral Hygiene Status among Yemenis.

Authors:  Abdulwahab I Al-Kholani
Journal:  Dent Res J (Isfahan)       Date:  2010

6.  Khat use as risk factor for psychotic disorders: a cross-sectional and case-control study in Somalia.

Authors:  Michael Odenwald; Frank Neuner; Maggie Schauer; Thomas Elbert; Claudia Catani; Birke Lingenfelder; Harald Hinkel; Heinz Häfner; Brigitte Rockstroh
Journal:  BMC Med       Date:  2005-02-12       Impact factor: 8.775

7.  Perceived Psychological, Economic, and Social Impact of Khat Chewing among Adolescents and Adults in Nekemte Town, East Welega Zone, West Ethiopia.

Authors:  Amsalu Taye Wondemagegn; Melese Chego Cheme; Kelemu Tilahun Kibret
Journal:  Biomed Res Int       Date:  2017-02-06       Impact factor: 3.411

8.  Khat Chewing and Type 2 Diabetes Mellitus.

Authors:  Mohammed Badedi; Hussain Darraj; Abdulrahman Hummadi; Abdullah Najmi; Yahiya Solan; Ibrahim Zakry; Abdullah Khawaji; Sayedah Zaylai; Norah Rajeh; Hassan Alhafaf; Wali Hakami; Awaji Bakkari; Maryam Kriry; Abdulraheem Dagreri; Ebrahim Haddad
Journal:  Diabetes Metab Syndr Obes       Date:  2020-02-10       Impact factor: 3.168

9.  Khat and stroke.

Authors:  Sanjay V Kulkarni; Yasir Ahamed A Mughani; Enass Hassan A Onbol; Punith Kempegowda
Journal:  Ann Indian Acad Neurol       Date:  2012-04       Impact factor: 1.383

10.  Epicardial coronary arteries in khat chewers presenting with myocardial infarction.

Authors:  Ahmed Al-Motarreb; Adel Shabana; Ayman El-Menyar
Journal:  Int J Vasc Med       Date:  2013-10-03
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  1 in total

1.  Protein-Ligand Identification and In Vitro Inhibitory Effects of Cathine on 11 Major Human Drug Metabolizing Cytochrome P450s.

Authors:  Sharoen Y M Lim; Jason Siau Ee Loo; Mustafa Alshagga; Mohammed A Alshawsh; Chin E Ong; Yan Pan
Journal:  Int J Toxicol       Date:  2022-06-04       Impact factor: 2.380

  1 in total

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