| Literature DB >> 33525745 |
Abd Elmoneim O Elkhalifa1, Eyad Alshammari1, Mohd Adnan2, Jerold C Alcantara3, Amir Mahgoub Awadelkareem1, Nagat Elzein Eltoum1, Khalid Mehmood4, Bibhu Prasad Panda5, Syed Amir Ashraf1.
Abstract
Recently, there has been a paradigm shift from conventional therapies to relatively safer phytotherapies. This divergence is crucial for the management of various chronic diseases. Okra (Abelmoschus esculentus L.) is a popular vegetable crop with good nutritional significance, along with certain therapeutic values, which makes it a potential candidate in the use of a variety of nutraceuticals. Different parts of the okra fruit (mucilage, seed, and pods) contain certain important bioactive components, which confer its medicinal properties. The phytochemicals of okra have been studied for their potential therapeutic activities on various chronic diseases, such as type-2 diabetes, cardiovascular, and digestive diseases, as well as the antifatigue effect, liver detoxification, antibacterial, and chemo-preventive activities. Moreover, okra mucilage has been widely used in medicinal applications such as a plasma replacement or blood volume expanders. Overall, okra is considered to be an easily available, low-cost vegetable crop with various nutritional values and potential health benefits. Despite several reports about its therapeutic benefits and potential nutraceutical significance, there is a dearth of research on the pharmacokinetics and bioavailability of okra, which has hampered its widespread use in the nutraceutical industry. This review summarizes the available literature on the bioactive composition of okra and its potential nutraceutical significance. It will also provide a platform for further research on the pharmacokinetics and bioavailability of okra for its possible commercial production as a therapeutic agent against various chronic diseases.Entities:
Keywords: antidiabetic; cardioprotective; functional foods; nutraceuticals; okra; phytotherapy
Mesh:
Substances:
Year: 2021 PMID: 33525745 PMCID: PMC7865958 DOI: 10.3390/molecules26030696
Source DB: PubMed Journal: Molecules ISSN: 1420-3049 Impact factor: 4.411