Literature DB >> 33525745

Okra (Abelmoschus Esculentus) as a Potential Dietary Medicine with Nutraceutical Importance for Sustainable Health Applications.

Abd Elmoneim O Elkhalifa1, Eyad Alshammari1, Mohd Adnan2, Jerold C Alcantara3, Amir Mahgoub Awadelkareem1, Nagat Elzein Eltoum1, Khalid Mehmood4, Bibhu Prasad Panda5, Syed Amir Ashraf1.   

Abstract

Recently, there has been a paradigm shift from conventional therapies to relatively safer phytotherapies. This divergence is crucial for the management of various chronic diseases. Okra (Abelmoschus esculentus L.) is a popular vegetable crop with good nutritional significance, along with certain therapeutic values, which makes it a potential candidate in the use of a variety of nutraceuticals. Different parts of the okra fruit (mucilage, seed, and pods) contain certain important bioactive components, which confer its medicinal properties. The phytochemicals of okra have been studied for their potential therapeutic activities on various chronic diseases, such as type-2 diabetes, cardiovascular, and digestive diseases, as well as the antifatigue effect, liver detoxification, antibacterial, and chemo-preventive activities. Moreover, okra mucilage has been widely used in medicinal applications such as a plasma replacement or blood volume expanders. Overall, okra is considered to be an easily available, low-cost vegetable crop with various nutritional values and potential health benefits. Despite several reports about its therapeutic benefits and potential nutraceutical significance, there is a dearth of research on the pharmacokinetics and bioavailability of okra, which has hampered its widespread use in the nutraceutical industry. This review summarizes the available literature on the bioactive composition of okra and its potential nutraceutical significance. It will also provide a platform for further research on the pharmacokinetics and bioavailability of okra for its possible commercial production as a therapeutic agent against various chronic diseases.

Entities:  

Keywords:  antidiabetic; cardioprotective; functional foods; nutraceuticals; okra; phytotherapy

Mesh:

Substances:

Year:  2021        PMID: 33525745      PMCID: PMC7865958          DOI: 10.3390/molecules26030696

Source DB:  PubMed          Journal:  Molecules        ISSN: 1420-3049            Impact factor:   4.411


  84 in total

1.  Antiproliferative and proapoptotic actions of okra pectin on B16F10 melanoma cells.

Authors:  Muriel Vayssade; Nipaporn Sengkhamparn; René Verhoef; Claire Delaigue; Oumou Goundiam; Pascale Vigneron; Alphons G J Voragen; Henk A Schols; Marie-Danielle Nagel
Journal:  Phytother Res       Date:  2010-07       Impact factor: 5.878

Review 2.  Genomic insights into the causes of type 2 diabetes.

Authors:  Claudia Langenberg; Luca A Lotta
Journal:  Lancet       Date:  2018-06-16       Impact factor: 79.321

3.  Efficacy and safety of Abelmoschus manihot for primary glomerular disease: a prospective, multicenter randomized controlled clinical trial.

Authors:  Li Zhang; Ping Li; Chang-ying Xing; Jiu-yang Zhao; Ya-ni He; Jian-qin Wang; Xiong-fei Wu; Zhang-suo Liu; Ai-ping Zhang; Hong-li Lin; Xiao-qiang Ding; Ai-ping Yin; Fa-huan Yuan; Ping Fu; Li Hao; Li-ning Miao; Ru-juan Xie; Rong Wang; Chun-hua Zhou; Guang-ju Guan; Zhao Hu; Shan Lin; Ming Chang; Miao Zhang; Li-qun He; Chang-lin Mei; Li Wang; Xiangmei Chen
Journal:  Am J Kidney Dis       Date:  2014-03-14       Impact factor: 8.860

4.  Antifungal screening of medicinal plants of British Columbian native peoples.

Authors:  A R McCutcheon; S M Ellis; R E Hancock; G H Towers
Journal:  J Ethnopharmacol       Date:  1994-12       Impact factor: 4.360

5.  Seed oil and fatty acid content in okra (Abelmoschus esculentus) and related species.

Authors:  Robert L Jarret; Ming Li Wang; Irvin J Levy
Journal:  J Agric Food Chem       Date:  2011-03-17       Impact factor: 5.279

Review 6.  Leukotriene A4 hydrolase: an emerging target of natural products for cancer chemoprevention and chemotherapy.

Authors:  Tam Thuy Lu Vo; Won-Jun Jang; Chul-Ho Jeong
Journal:  Ann N Y Acad Sci       Date:  2018-07-29       Impact factor: 5.691

Review 7.  Lectin-Carbohydrate Interactions: Implications for the Development of New Anticancer Agents.

Authors:  Evellyne de Oliveira Figueiroa; Cassia Regina Albuquerque da Cunha; Priscilla B S Albuquerque; Raiana Apolinario de Paula; Mary Angela Aranda-Souza; Matheus Silva Alves; Adrielle Zagmignan; Maria G Carneiro-da-Cunha; Luis Claudio Nascimento da Silva; Maria Tereza Dos Santos Correia
Journal:  Curr Med Chem       Date:  2017-11-17       Impact factor: 4.530

8.  Composition analysis and immuno-modulatory effect of okra (Abelmoschus esculentus L.) extract.

Authors:  Shyang-Chwen Sheu; Mei-Huei Lai
Journal:  Food Chem       Date:  2012-04-03       Impact factor: 7.514

9.  Huangkui capsule, an extract from Abelmoschus manihot (L.) medic, improves diabetic nephropathy via activating peroxisome proliferator-activated receptor (PPAR)-α/γ and attenuating endoplasmic reticulum stress in rats.

Authors:  Jing Ge; Jun-Jun Miao; Xin-Yi Sun; Jiang-Yi Yu
Journal:  J Ethnopharmacol       Date:  2016-05-17       Impact factor: 4.360

10.  Content determination of the flavonoids in the different parts and different species of Abelmoschus esculentus L. by reversed phase-high performance liquid chromatograph and colorimetric method.

Authors:  Yin Lin; Min-Feng Lu; Hai-Bing Liao; Yu-Xian Li; Wei Han; Ke Yuan
Journal:  Pharmacogn Mag       Date:  2014-07       Impact factor: 1.085

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  9 in total

1.  The complete mitochondrial genome of okra (Abelmoschus esculentus): using nanopore long reads to investigate gene transfer from chloroplast genomes and rearrangements of mitochondrial DNA molecules.

Authors:  Jihan Li; Jingling Li; Yubo Ma; Lu Kou; Juanjuan Wei; Weixing Wang
Journal:  BMC Genomics       Date:  2022-06-29       Impact factor: 4.547

2.  Identification and Quantification of Flavonoids in Okra (Abelmoschus esculentus L. Moench) and Antiproliferative Activity In Vitro of Four Main Components Identified.

Authors:  Jing Yang; Xiaoqi Chen; Shuaiqi Rao; Yaochen Li; Yunxiang Zang; Biao Zhu
Journal:  Metabolites       Date:  2022-05-26

3.  Seasonal Variations in Bioaccumulation and Translocation of Toxic Heavy Metals in the Dominant Vegetables of East Kolkata Wetlands: a Case Study with Suggestive Ecorestorative Strategies.

Authors:  Sangita Agarwal; Pritam Mukherjee; Prosenjit Pramanick; Abhijit Mitra
Journal:  Appl Biochem Biotechnol       Date:  2022-07-19       Impact factor: 3.094

4.  Efficacy and Mechanism of Thymol/KGM/LG Edible Coating Solution on Inhibition of Mucor circinelloides Isolated From Okra.

Authors:  Qinqiu Zhang; Wen Qin; Xinjie Hu; Jing Yan; Yaowen Liu; Zhuwei Wang; Lang Liu; Jie Ding; Peng Huang; Jiya Wu
Journal:  Front Microbiol       Date:  2022-05-16       Impact factor: 6.064

5.  Phytochemical and In Silico ADME/Tox Analysis of Eruca sativa Extract with Antioxidant, Antibacterial and Anticancer Potential against Caco-2 and HCT-116 Colorectal Carcinoma Cell Lines.

Authors:  Amir Mahgoub Awadelkareem; Eyad Al-Shammari; Abd Elmoneim O Elkhalifa; Mohd Adnan; Arif Jamal Siddiqui; Mejdi Snoussi; Mohammad Idreesh Khan; Z R Azaz Ahmad Azad; Mitesh Patel; Syed Amir Ashraf
Journal:  Molecules       Date:  2022-02-19       Impact factor: 4.411

6.  Effect of the Ethanol Extract of Red Okra Pods (Abelmoschus esculentus (L.) Moench) to Inhibit Cervical Cancer Cells Growth through Cell Cycle-Associated Oncogenes.

Authors:  Nabilatun Nisa; Sri Puji Astuti Wahyuningsih; Win Darmanto; Putut Rakhmad Purnama; Firli Rahmah Primula Dewi; Tipuk Soegiarti; Deya Karsari
Journal:  Scientifica (Cairo)       Date:  2022-04-26

7.  Systematic screening and validation of reliable reference genes for qRT-PCR analysis in Okra (Abelmoschus esculentus L.).

Authors:  Jing-Rong Zhang; Yuan-Yuan Feng; Ma-Jin Yang; Yu Xiao; Yu-Shan Liu; Yuan Yuan; Zhen Li; Yan Zhang; Ming Zhuo; Jun Zhang; Cai-Xia Li
Journal:  Sci Rep       Date:  2022-07-28       Impact factor: 4.996

Review 8.  "Planeterranea": An attempt to broaden the beneficial effects of the Mediterranean diet worldwide.

Authors:  Claudia Vetrani; Prisco Piscitelli; Giovanna Muscogiuri; Luigi Barrea; Daniela Laudisio; Chiara Graziadio; Francesca Marino; Annamaria Colao
Journal:  Front Nutr       Date:  2022-09-02

9.  Development and Characterization of Novel Biopolymer Derived from Abelmoschus esculentus L. Extract and Its Antidiabetic Potential.

Authors:  Abd Elmoneim O Elkhalifa; Eyad Al-Shammari; Mohd Adnan; Jerold C Alcantara; Khalid Mehmood; Nagat Elzein Eltoum; Amir Mahgoub Awadelkareem; Mushtaq Ahmad Khan; Syed Amir Ashraf
Journal:  Molecules       Date:  2021-06-12       Impact factor: 4.411

  9 in total

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