Literature DB >> 33523422

Approaches to Fracture Risk Assessment and Prevention.

Sanford Baim1, Robert Blank2.   

Abstract

PURPOSE OF REVIEW: To critically assess recent evidence concerning osteoporosis fracture risk. RECENT
FINDINGS: Robust instruments exist for predicting factures incorporating well-documented risk factors especially prior fracture whose magnitude varies with site, occurrence time, and age. Stratifying time-since-prior fracture has resulted in the concept of imminent fracture risk and increased focus on secondary fracture prevention. Secondary fracture prevention recommendations include fracture liaison service, pharmacologic and non-pharmacologic multidisciplinary intervention, and communicating that fractures in older adults are the predictable consequence of underlying osteoporosis rather than unfortunate accidents. Quality improvement in osteoporosis care includes diagnosing osteoporosis on the basis of clinical fractures rather than exclusively relying on bone density testing; applying diagnostic rather than screening approaches to patients with prior fractures; regularly updating fall and fracture histories; performing a physical exam focused on spinal curvature, posture, and musculoskeletal function; reviewing images to identify prevalent fractures that may have been missed; and general use of fracture risk algorithms at all stages of osteoporosis management. Communicating effectively with patients about osteoporosis and fractures, their consequences, and pharmacological and non-pharmacological management is the cornerstone of high-value care.

Entities:  

Keywords:  Comorbidity; Falls; Fracture; Fracture liaison service; Risk algorithms; Secondary prevention

Mesh:

Year:  2021        PMID: 33523422     DOI: 10.1007/s11914-021-00659-x

Source DB:  PubMed          Journal:  Curr Osteoporos Rep        ISSN: 1544-1873            Impact factor:   5.096


  72 in total

1.  Lifetime risks of hip, Colles', or vertebral fracture and coronary heart disease among white postmenopausal women.

Authors:  S R Cummings; D M Black; S M Rubin
Journal:  Arch Intern Med       Date:  1989-11

Review 2.  FRAX and its applications to clinical practice.

Authors:  John A Kanis; Anders Oden; Helena Johansson; Fredrik Borgström; Oskar Ström; Eugene McCloskey
Journal:  Bone       Date:  2009-02-03       Impact factor: 4.398

Review 3.  Worldwide Fracture Prediction.

Authors:  Ghada El-Hajj Fuleihan; Marlene Chakhtoura; Jane A Cauley; Nariman Chamoun
Journal:  J Clin Densitom       Date:  2017-07-19       Impact factor: 2.617

4.  Incidence and economic burden of osteoporosis-related fractures in the United States, 2005-2025.

Authors:  Russel Burge; Bess Dawson-Hughes; Daniel H Solomon; John B Wong; Alison King; Anna Tosteson
Journal:  J Bone Miner Res       Date:  2007-03       Impact factor: 6.741

5.  Insulin-induced cytoplasmic alkalinization and glucose transport in muscle cells.

Authors:  A Klip; T Ramlal; E J Cragoe
Journal:  Am J Physiol       Date:  1986-05

6.  Residual lifetime risk of fractures in women and men.

Authors:  Nguyen D Nguyen; Henrik G Ahlborg; Jacqueline R Center; John A Eisman; Tuan V Nguyen
Journal:  J Bone Miner Res       Date:  2007-06       Impact factor: 6.741

7.  Mortality after osteoporotic fractures.

Authors:  O Johnell; J A Kanis; A Odén; I Sernbo; I Redlund-Johnell; C Petterson; C De Laet; B Jönsson
Journal:  Osteoporos Int       Date:  2003-10-30       Impact factor: 4.507

8.  Relative survival after hospitalisation for hip fracture in older people in New South Wales, Australia.

Authors:  D M Hindmarsh; A Hayen; C F Finch; J C T Close
Journal:  Osteoporos Int       Date:  2008-06-07       Impact factor: 4.507

9.  Mortality risk associated with low-trauma osteoporotic fracture and subsequent fracture in men and women.

Authors:  Dana Bliuc; Nguyen D Nguyen; Vivienne E Milch; Tuan V Nguyen; John A Eisman; Jacqueline R Center
Journal:  JAMA       Date:  2009-02-04       Impact factor: 56.272

10.  Osteoporosis medication use after hip fracture in U.S. patients between 2002 and 2011.

Authors:  Daniel H Solomon; Stephen S Johnston; Natalie N Boytsov; Donna McMorrow; Joseph M Lane; Kelly D Krohn
Journal:  J Bone Miner Res       Date:  2014-09       Impact factor: 6.741

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  1 in total

1.  Evaluating the performance of the Charlson Comorbidity Index (CCI) in fracture risk prediction and developing a new Charlson Fracture Index (CFI): a register-based cohort study.

Authors:  A Clausen; S Möller; M K Skjødt; B H Bech; K H Rubin
Journal:  Osteoporos Int       Date:  2022-01-06       Impact factor: 4.507

  1 in total

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