Literature DB >> 33517254

Classification of reflux patterns in patients with great saphenous vein insufficiency and correlation with clinical severity.

Sezen Yılmaz1, Burçak Çakır Peköz2, Neris Dincer1, Sinan Deniz3, Levent Oğuzkurt3.   

Abstract

PURPOSE: This study aims to establish a clinically applicable classification of reflux patterns in patients with great saphenous vein insufficiency and to evaluate the relationship between this classification, the demographics, and severity of clinical findings.
METHODS: This is a retrospective study from prospectively collected data of 503 patients who had the complaint of varicose vein. All patients had complete physical examination and their medical history was recorded. Lower limbs of all patients were examined with Doppler ultrasonography. A total of 787 limbs with great saphenous vein insufficiency were included in the analysis. The reflux patterns of great saphenous vein insufficiency were classified into 4 types as: type 1, great saphenous vein reflux without involvement of malleolar region and saphenofemoral junction (SFJ); type 2, reflux involving malleolar region with competent SFJ; type 3, reflux involving SFJ with competent malleolar region; and type 4, reflux involving both the SFJ and the malleolar region. We evaluated the association between the classification of great saphenous vein insufficiency and age, sex, body mass index (BMI), disease duration, clinical, etiological, anatomical and pathophysiological elements (CEAP) classification and venous clinical severity score (VCSS).
RESULTS: The mean age of the patients was 45.3±11.7 years, with a male-to-female ratio of 2:3. The most common reflux pattern in patients with great saphenous vein insufficiency was type 3 (48.9%), while 14.8% of patients had type 1, 10.4% had type 2, and 25.7% had type 4. Patients with type I reflux pattern were younger in age (p = 0.002), had lower BMI (p = 0.002), fewer number of children (p = 0.008), as well as milder clinical severity score (p = 0.002) compared to other reflux types. Duration of disease symptoms was not significantly correlated with the reflux patterns, but VCSS increased with the involvement of malleolar region as in type 2 compared to type 1 (2.82±1.67 vs. 2.74±2.31), and further increased with the involvement of SFJ as in type 3 (4.13±2.92 vs. 2.82±1.67). Patients with diffuse reflux pattern (type 4) had the most severe clinical presentation (4.59±2.9).
CONCLUSION: We developed a clinically applicable classification of reflux patterns in patients with great saphenous vein insufficiency based on the involvement of malleolar region and/or SFJ. We showed an association between weight, BMI, VCSS, CEAP classification and the extent of insufficiency.

Entities:  

Year:  2021        PMID: 33517254      PMCID: PMC7963375          DOI: 10.5152/dir.2021.19580

Source DB:  PubMed          Journal:  Diagn Interv Radiol        ISSN: 1305-3825            Impact factor:   2.630


  21 in total

Review 1.  Surgical and endovascular treatment of lower extremity venous insufficiency.

Authors:  John J Bergan; Norman H Kumins; Erik L Owens; Steven R Sparks
Journal:  J Vasc Interv Radiol       Date:  2002-06       Impact factor: 3.464

Review 2.  Invasive therapeutic options in truncal varicosity of the great saphenous vein.

Authors:  V Hach-Wunderle; W Hach
Journal:  Vasa       Date:  2006-08       Impact factor: 1.961

Review 3.  Venous Clinical Severity Score and quality-of-life assessment tools: application to vein practice.

Authors:  M A Vasquez; C E Munschauer
Journal:  Phlebology       Date:  2008       Impact factor: 1.740

Review 4.  The epidemiology of chronic venous insufficiency and varicose veins.

Authors:  Jennifer L Beebe-Dimmer; John R Pfeifer; Jennifer S Engle; David Schottenfeld
Journal:  Ann Epidemiol       Date:  2005-03       Impact factor: 3.797

5.  Reflux patterns and risk factors of primary varicose veins’ clinical severity.

Authors:  M García-Gimeno; S Rodríguez-Camarero; S Tagarro-Villalba; E Ramalle-Gomara; J A Ajona García; M A González Arranz; D López García; E González-González; C Vaquero Puerta
Journal:  Phlebology       Date:  2013-04       Impact factor: 1.740

6.  [Special diagnostic and therapeutic procedure for the incomplete form of primary varicosis].

Authors:  C Langer; W Hach
Journal:  Z Hautkr       Date:  1982-08-01

7.  Chronic Venous Insufficiency: a Frequently Underdiagnosed and Undertreated Pathology.

Authors:  Marilena Spiridon; Dana Corduneanu
Journal:  Maedica (Bucur)       Date:  2017-01

8.  Progression of reflux patterns in saphenous veins of women with chronic venous valvular insufficiency.

Authors:  C A Engelhorn; R Manetti; M M Baviera; G M Bombonato; M Lonardoni; M F Cassou; A L Engelhorn; S X Salles-Cunha
Journal:  Phlebology       Date:  2011-09-08       Impact factor: 1.740

9.  Endovascular laser therapy for varicose veins: an evidence-based analysis.

Authors: 
Journal:  Ont Health Technol Assess Ser       Date:  2010-04-01

10.  Chronic venous disorders: correlation between visible signs, symptoms, and presence of functional disease.

Authors:  Roberto Chiesa; Enrico Maria Marone; Costanzo Limoni; Marina Volontè; Orlando Petrini
Journal:  J Vasc Surg       Date:  2007-06-27       Impact factor: 4.268

View more
  1 in total

1.  Blood Flow Analysis of the Great Saphenous Vein in the Su-Pine Position in Clinical Manifestations of Varicose Veins of Different Severities: Application of Phase-Contrast Magnetic Resonance Imaging Data.

Authors:  Yuan-Hsi Tseng; Chien-Wei Chen; Min-Yi Wong; Teng-Yao Yang; Yu-Hui Lin; Bor-Shyh Lin; Yao-Kuang Huang
Journal:  Diagnostics (Basel)       Date:  2022-01-05
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.