Literature DB >> 33512620

[Myoepithelial carcinoma of the parotid gland: a rare tumor with diagnostic challenges].

Elias Tenner1, Edda Menke-Lechner1, Stefan Edlinger1, Melitta Kitzwoegerer2, Georg Sprinzl1.   

Abstract

We report on the occurrence of a myoepithelial carcinoma (MC) of the parotid gland in a 58-year-old female patient, 6 years after total parotidectomy of a locoregional myoepithelioma. Due to the rapid growth in the former resection area, panendoscopy and tumor extirpation of the right parotid region were performed. From a histomorphological and cytomorphological point of view, a hyalinized clear cell carcinoma of the salivary gland was originally diagnosed. After further immunohistochemical investigations and preparation of deeper section levels the morphological picture and immunohistochemical expression pattern corresponded to a myoepithelial carcinoma of the salivary gland, with focal lateral excision margins. Based on the radiological impression of suspicious lymph nodes during the staging examinations and the perineural invasion in the histological findings, modified radical neck dissection of the ipsilateral levels I-V was performed. All lymph nodes were histologically negative. An adjuvant radiotherapy was then initiated. The patient is tumor-free 7 months after surgery and after completing the adjuvant radiation treatment. Clinical assessment of the facial nerve showed House-Brackmann grade 5 facial palsy. The aim of this case report is to describe the difficulties in the diagnostics and treatment of this rare entity.
© 2021. Springer-Verlag GmbH Austria, ein Teil von Springer Nature.

Entities:  

Keywords:  Immunohistochemistry; Myoepithelial neoplasia; Neck dissection; Parotid gland; Parotidectomy, revision

Mesh:

Year:  2021        PMID: 33512620     DOI: 10.1007/s10354-020-00811-9

Source DB:  PubMed          Journal:  Wien Med Wochenschr        ISSN: 0043-5341


  9 in total

1.  Myoepithelial carcinoma of the parotid: a rare tumour that may provide diagnostic difficulty.

Authors:  Emily Skelton; Amanda C Jewison; Keith Ramesar; David Howlett
Journal:  BMJ Case Rep       Date:  2015-02-26

2.  Myoepithelial neoplasia of the submandibular gland: case report and therapeutic considerations.

Authors:  Jayakar V Nayak; J Thomas Molina; Jonathan C Smith; Barton F Branstetter; Jennifer L Hunt; Carl H Snyderman
Journal:  Arch Otolaryngol Head Neck Surg       Date:  2003-03

Review 3.  [Updates on tumours of the salivary glands : 2017 WHO classification].

Authors:  S Ihrler; O Guntinas-Lichius; C Haas; M Mollenhauer
Journal:  Pathologe       Date:  2018-02       Impact factor: 1.011

4.  Radiotherapy alone or combined with surgery for salivary gland carcinoma.

Authors:  William M Mendenhall; Christopher G Morris; Robert J Amdur; John W Werning; Douglas B Villaret
Journal:  Cancer       Date:  2005-06-15       Impact factor: 6.860

Review 5.  Salivary gland myoepithelial carcinoma.

Authors:  S Vilar-González; K Bradley; J Rico-Pérez; P Vogiatzis; D Golka; A Nigam; M Sivaramalingam; S Kazmi
Journal:  Clin Transl Oncol       Date:  2015-07-02       Impact factor: 3.405

6.  A prognostic index for predicting lymph node metastasis in minor salivary gland cancer.

Authors:  Shane Lloyd; James B Yu; Douglas A Ross; Lynn D Wilson; Roy H Decker
Journal:  Int J Radiat Oncol Biol Phys       Date:  2010-01-01       Impact factor: 7.038

7.  Primary clear cell carcinoma of parotid gland: Case report and review of literature.

Authors:  Marta Saldaña Rodríguez; Maria Fe García Reija; Irene González Rodilla
Journal:  J Oral Maxillofac Pathol       Date:  2013-01

8.  Invasive myoepithelial carcinoma ex pleomorphic adenoma of the major salivary gland: two case reports.

Authors:  Takahiro Wakasaki; Marie Kubota; Yutaka Nakashima; Eri Tomonobe; Takenao Mihara; Junichi Fukushima
Journal:  BMC Cancer       Date:  2016-10-28       Impact factor: 4.430

9.  Epithelioid myoepithelioma of the accessory parotid gland: pathological and magnetic resonance imaging findings.

Authors:  Hiroyoshi Iguchi; Kei Yamada; Hideo Yamane; Shigeo Hashimoto
Journal:  Case Rep Oncol       Date:  2014-05-16
  9 in total

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